Dieta, cetogênica, suplementos, agonistas de GLP-1 e metabolismo. 48 artigos nesta área.
Lipedema is a chronic female disease characterized by a painful accumulation of adipose tissue in the limbs. Plasma fatty acid (FA) composition has been proposed as a potential modulator of pain. However, the pathophysiology…
Lundanes J et al. · Nutrition journal · 11 mar 2026
Lipoedema is a chronic, progressive condition characterised by disproportionate fat accumulation in the lower extremities, often misdiagnosed due to symptom overlap with obesity. Weight management is a key component of lipoedema…
Pajaziti Q et al. · Clinical obesity · 1 fev 2026
Lipedema is a chronic, progressive condition characterized by symmetrical accumulation of adipose tissue, predominantly in women's lower extremities. It is frequently associated with pain, reduced mobility, and psychological…
de Oliveira J, de Paula ACP, Guimarães VHD · Maturitas · 5 set 2025
Ketosis seems to attenuate, or prevent, the rise in both ghrelin concentrations and subjective hunger ratings that follow weight loss. However, most of the previous studies have employed very-low energy diets (VLED) and are…
Lundanes J et al. · Clinical nutrition ESPEN · 19 nov 2024
Lipedema is a frequently misdiagnosed condition in women, often mistaken for obesity, which significantly deteriorates both quality of life and physical health. Recognizing the necessity for holistic treatment strategies,…
Amato ACM, Amato JLS, Benitti DA · Nutrients · 27 set 2024
The primary objective of this study was to evaluate the effect of a low-carbohydrate diet (LCD) compared with a control diet on pain in female patients with lipedema. The secondary objectives were to compare the impact of the two…
Lundanes J et al. · Obesity (Silver Spring, Md.) · 16 abr 2024
Lipedema is a chronic adipose tissue disorder that predominantly affects women, although some rare cases do occur in men. We report the case of a 32-year-old man with symmetrical, lower-limb fat accumulation, foot sparing, pain,…
Kaefer M et al. · Jornal vascular brasileiro · 9 out 2026
Sem abstract disponível no PubMed.
Litaiem N, Slouma M · International journal of dermatology · 7 out 2026
Lipoedema is a painful adipose tissue disorder marked by disproportionate limb fat and often misclassified as generalized obesity or lymphoedema. This review examines its metabolic phenotype and implications for cardiometabolic…
Varghese RT, Varghese DG · Clinical obesity · 1 out 2026
This study aimed to compare 12-week changes in body composition and anthropometric parameters between standard-dose and lower-dose tirzepatide escalation regimens in women with lipedema, with particular emphasis on changes in fat…
Frederichi de Souza P, Patriani G, Ribeiro Pacheco CM · Cureus · 23 set 2026
Low-carbohydrate diets (LCDs) have been suggested as a potential treatment option for females with lipedema, due to their superiority in reducing pain, possibly through improvements in insulin dynamics. The objective of this…
Lundanes J et al. · Frontiers in cell and developmental biology · 15 set 2026
Lipedema is a chronic medical condition primarily affecting women, characterized by bilateral, symmetrical, disproportionate fat deposition in the lower limbs, and sometimes arms and lower trunk. Pharmacological interventions…
Srinivasan A et al. · Obesity pillars · 14 ago 2026
Lipedema, a chronic condition primarily affecting women, is characterized by abnormal subcutaneous fat accumulation and swelling in the extremities (while sparing the hands, feet, and trunk). This disease is associated with…
Atabilen Pınar B et al. · Nutrition reviews · 1 ago 2026
To examine the associations of ultra-processed food (UPF) consumption, dietary inflammatory index (DII), and Mediterranean diet adherence with pain severity, physical quality of life, body composition, and inflammatory markers in…
Arslan N · Frontiers in nutrition · 30 jun 2026
Lipedema is a chronic adipose tissue disorder with disproportionate fat accumulation in the extremities and is often misdiagnosed as obesity. Although women with lipedema appear to be metabolically distinct from body mass index…
Kempa S et al. · Frontiers in endocrinology · 5 jun 2026
Lipedema is a chronic disorder characterized by disproportionate accumulation of subcutaneous fat, most commonly affecting the extremities, and is associated with pain, inflammation, and fibrosis. Effective medical therapies are…
Mohseni Y et al. · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 18 mai 2026
Lipedema is a chronic female disease characterized by a painful accumulation of adipose tissue in the limbs. Plasma fatty acid (FA) composition has been proposed as a potential modulator of pain. However, the pathophysiology…
Lundanes J et al. · Nutrition journal · 11 mar 2026
Lipedema is a lipodystrophic disease characterized primarily by a disproportionate increase in lower body subcutaneous fat. Although moderate weight loss decreases lower body fat mass in women with obesity and lipedema, it is…
De Girolamo G et al. · JCEM case reports · 27 fev 2026
Background Lipedema is characterized by disproportionate gluteofemoral adiposity with anti-inflammatory properties. We hypothesized that this phenotype may confer immunological protection against T-helper 1 (Th1)-mediated…
Amato AC, Amato JL, Benitti D · Cureus · 25 fev 2026
Lipoedema is a chronic, progressive condition characterised by disproportionate fat accumulation in the lower extremities, often misdiagnosed due to symptom overlap with obesity. Weight management is a key component of lipoedema…
Pajaziti Q et al. · Clinical obesity · 1 fev 2026
Lipedema is a multifactorial disorder with a negative evolutionary trend, influenced by genetic, hormonal, metabolic, and vascular factors that are not fully understood. Inflammation is a typical feature of lipedema and can be…
Cannataro R, Abrego-Guandique DM, Cione E · Frontiers in nutrition · 29 jan 2026
Lipedema is a chronic female disease, characterized by an excessive accumulation of subcutaneous adipose tissue in the limbs and is commonly mistaken for obesity, although the two conditions often coexist. Obesity is associated…
Lundanes J et al. · Frontiers in nutrition · 17 dez 2025
Lipedema is a painful chronic disease characterized by symmetric fat tissue accumulation in the lower extremities. Inflammation of the subcutaneous adipose tissue causes pain, edema, and various functional limitations, making…
Aydin A, Bilgic P · Current nutrition reports · 18 out 2025
Background Lipedema is a chronic adipose tissue disorder affecting primarily women and is increasingly associated with immune dysregulation and intestinal permeability. Food-specific IgG testing has been explored in various…
Amato AC, Amato JS, Benitti D · Cureus · 3 out 2025
Background/Objectives: Lipedema is a chronic adipose tissue disorder characterized by disproportionate fat accumulation and inflammation, predominantly affecting women. While recent evidence suggests a systemic pro-inflammatory…
Jeziorek M et al. · Nutrients · 20 set 2025
Lipedema is a chronic, progressive condition characterized by symmetrical accumulation of adipose tissue, predominantly in women's lower extremities. It is frequently associated with pain, reduced mobility, and psychological…
de Oliveira J, de Paula ACP, Guimarães VHD · Maturitas · 5 set 2025
Background: Lipedema is a chronic disease of subcutaneous adipose tissue that predominantly affects women and is frequently associated with endocrinopathies such as insulin resistance and obesity. Its pathogenesis is still…
Patton L et al. · Clinics and practice · 7 jul 2025
Lipedema is an abnormal accumulation of adipose tissue, predominantly observed in women, characterised by symmetrical fat deposition and tactile sensitivity in the extremities, affecting both sides of the body. This condition can…
Sanlier N, Baltacı S · Current obesity reports · 26 mai 2025
Lipedema is considered an inflammation-related disease, and low-carbohydrate ketogenic diets may help reduce inflammation. However, no randomized controlled trials have investigated the effect of a low-carbohydrate ketogenic diet…
Lundanes J et al. · Current developments in nutrition · 20 fev 2025
The Ketogenic Diet (KD) is currently the most widely studied nutritional approach for patients with lipedema, although its use may cause important drawbacks especially in case of comorbidities. A Modified Mediterranean Diet…
Fedre B, Dessalvi S, Boccardo F · Lymphology · 1 jan 2025
This case report explores the use of radio electric asymmetric conveyor (REAC) technology for chronic pain management, functional limitations, and metabolic dysfunction in a 67-year-old female with rheumatoid arthritis, advanced…
Renck AC, Fontani V, Rinaldi S · Cureus · 23 nov 2024
Ketosis seems to attenuate, or prevent, the rise in both ghrelin concentrations and subjective hunger ratings that follow weight loss. However, most of the previous studies have employed very-low energy diets (VLED) and are…
Lundanes J et al. · Clinical nutrition ESPEN · 19 nov 2024
Lipedema is a common, yet underdiagnosed, subcutaneous adipose tissue (SAT) disorder. The main characteristics are SAT expansion in the lower extremities and arms, pain, and tenderness to palpation. It remains unknown if a…
Lundanes J et al. · Frontiers in nutrition · 7 nov 2024
Lipedema is a frequently misdiagnosed condition in women, often mistaken for obesity, which significantly deteriorates both quality of life and physical health. Recognizing the necessity for holistic treatment strategies,…
Amato ACM, Amato JLS, Benitti DA · Nutrients · 27 set 2024
This study aimed to develop a novel predictive equation for calculating resting metabolic rate (RMR) in women with lipedema. We recruited 119 women diagnosed with lipedema from the Angiology Outpatient Clinic at Wroclaw Medical…
Jeziorek M et al. · Metabolites · 19 abr 2024
The primary objective of this study was to evaluate the effect of a low-carbohydrate diet (LCD) compared with a control diet on pain in female patients with lipedema. The secondary objectives were to compare the impact of the two…
Lundanes J et al. · Obesity (Silver Spring, Md.) · 16 abr 2024
Sem abstract disponível no PubMed.
Oliveira Jd · Revista da Associacao Medica Brasileira (1992) · 18 dez 2023
This study aimed to assess the potential benefits of a low-carbohydrate, high-fat (LCHF) diet on body composition, leg volume, and pain reduction in women with lipedema compared to overweight or women with obesity. The study…
Jeziorek M et al. · Journal of obesity · 18 nov 2023
This review aims to provide an overview of the current evidence on the efficacy, also considering the anti-inflammatory properties and safety of very low-calorie ketogenic diet (VLCKD) as a potential treatment for lipedema,…
Verde L et al. · Current obesity reports · 4 nov 2023
In recent years, the use of the ketogenic diet as a proper nutritional treatment for lipedema has been hypothesized in the literature. This is the first clinical study evaluating the ketogenic diet and carboxytherapy in lipedema…
Di Renzo L et al. · Nutrients · 20 ago 2023
The aim of this study was to evaluate alterations in blood parameters after a low-carbohydrate high-fat (LCHF) diet in women with lipedema in comparison to overweight or obese women. A total of 115 women were classified into two…
Jeziorek M et al. · Nutrients · 2 jun 2023
Background: An adequate dietary energy supply is particularly important in patients with lipedema as it promotes weight and fat loss. Accurate estimation of resting metabolic rate (RMR) allows implementing a proper calorie…
Jeziorek M et al. · Lymphatic research and biology · 20 jan 2023
Lipedema, a chronic disease characterized by excessive fatty tissue deposition in the hips, buttocks, and lower legs, significantly negatively impacts the quality of life of those affected. This disease, which almost exclusively…
Kunzová M · Casopis lekaru ceskych · 1 jan 2023
Sem abstract disponível no PubMed.
Saalbach A, Kunz M · Frontiers in immunology · 29 dez 2022
Lipedema is a chronic disease that mostly manifests in females as the abnormal distribution of subcutaneous adipose connective tissue, usually coupled with bruising, pain, and edema. Lipedema molecular pathophysiology is…
Bonetti G et al. · Journal of preventive medicine and hygiene · 17 out 2022
Lipedema is a disorder characterized by an excessive accumulation of subcutaneous body fat, mainly bilateral and symmetrical accumulation of fat deposits, particularly in the lower extremities excluding feet. Pain (spontaneous or…
Jeziorek M et al. · Diabetes, metabolic syndrome and obesity : targets and therapy · 22 ago 2022
Lipedema is an underdiagnosed condition in women, characterized by a symmetrical increase in subcutaneous adipose tissue (SAT) in the lower extremities, sparing the trunk. The lipedema SAT has been found to be resistant to diet,…
Sørlie V et al. · Obesity science & practice · 21 abr 2022
Lipedema is a pathology of adipose tissue, still of unclear etiology and challenging to diagnose. For these reasons, a therapeutic approach is also complex and sometimes controversial. The inflammation state present in lipedema…
Cannataro R et al. · Life (Basel, Switzerland) · 15 dez 2021
BACKGROUND Lipedema is a common condition that presents as excessive fat deposition in the extremities, initially sparing the trunk, ankles, and feet, and is found mainly in women, usually occurring after puberty or pregnancy.…
Wright TF, Herbst KL · The American journal of case reports · 7 mai 2021
Lipoedema is a subcutaneous adipose tissue disease characterized by the increase in the amount and structure of fat mass (FM) in specific areas, causing pain and discomfort. 95% of patients fail to lose weight in the lipoedema…
Di Renzo L et al. · Nutrients · 25 jan 2021
Lipedema (LI) is a common yet misdiagnosed condition, often misconstrued with obesity. LI affects women almost exclusively, and its painful and life-changing symptoms have long been thought to be resistant to the lifestyle…
Keith L et al. · Medical hypotheses · 27 nov 2020
Adipose tissue insulin resistance has been observed in obese subjects and is considered an early metabolic defect that precedes insulin resistance in muscle and liver. Although Asians can readily develop metabolic disease without…
Sugimoto D et al. · The Journal of clinical endocrinology and metabolism · 1 jun 2019
We assessed body composition, bone mineral density (BMD), glucose and lipids in Williams syndrome (WS), a rare microdeletion disorder. Individuals with WS had outpatient assessment at Massachusetts General Hospital. Controls were…
Shaikh S et al. · Clinical endocrinology · 18 set 2018
Sem abstract disponível no PubMed.
Reinharez D · Soins; la revue de reference infirmiere · 1 mar 1983