Ensaio clínico randomizado

14 artigos deste tipo, do mais recente ao mais antigo.

Nível de evidência 4 de 5

Liposuction versus conservative therapy for patients with lipoedema in Germany: a multicentre, randomised controlled clinical trial

Lipoedema is a painful, chronic disease of the subcutaneous adipose tissue, predominantly affecting women. Conservative complex decongestive therapy is the standard of care but offers limited symptom relief. Liposuction appears…

Podda M et al. · Lancet (London, England) · 5 set 2026

Nível de evidência 4 de 5

Changes in plasma fatty acid composition in females with lipedema following low-carbohydrate vs low-fat diets and associations with pain reduction

Lipedema is a chronic female disease characterized by a painful accumulation of adipose tissue in the limbs. Plasma fatty acid (FA) composition has been proposed as a potential modulator of pain. However, the pathophysiology…

Lundanes J et al. · Nutrition journal · 11 mar 2026

Nível de evidência 4 de 5

Effects of multimodal exercise program on edema, pain, exercise capacity, lower extremity muscle strength and function in patients with lipedema

Objectives: This study aimed to examine the effects of a multimodal exercise program on edema, pain, exercise capacity, lower extremity muscle strength, and function in patients with lipedema.Methods: The patients diagnosed with…

Sakizli Erdal E et al. · Phlebology · 15 mai 2025

Nível de evidência 4 de 5

Gastrointestinal hormones and subjective ratings of appetite after low-carbohydrate vs low-fat low-energy diets in females with lipedema - A randomized controlled trial

Ketosis seems to attenuate, or prevent, the rise in both ghrelin concentrations and subjective hunger ratings that follow weight loss. However, most of the previous studies have employed very-low energy diets (VLED) and are…

Lundanes J et al. · Clinical nutrition ESPEN · 19 nov 2024

Nível de evidência 4 de 5

Effect of a low-carbohydrate diet on pain and quality of life in female patients with lipedema: a randomized controlled trial

The primary objective of this study was to evaluate the effect of a low-carbohydrate diet (LCD) compared with a control diet on pain in female patients with lipedema. The secondary objectives were to compare the impact of the two…

Lundanes J et al. · Obesity (Silver Spring, Md.) · 16 abr 2024

Nível de evidência 4 de 5

Effect of pneumatic compression device and stocking use on symptoms and quality of life in women with lipedema: A proof-in-principle randomized trial

Does short-term use of pneumatic compression devices (PCD) and off-the-shelf compression alleviate symptoms and improve quality of life in women with lipedema and secondary lipolymphedema? Prospective, randomized controlled,…

Wright T, Scarfino CD, O'Malley EM · Phlebology · 15 dez 2022

Nível de evidência 4 de 5

A randomised controlled multicentre investigator-blinded clinical trial comparing efficacy and safety of surgery versus complex physical decongestive therapy for lipedema (LIPLEG)

Lipedema is a chronic disorder of the adipose tissue that affects mainly women, characterised by symmetrical, excessive fatty tissue on the legs and pain. Standard conservative treatment is long-term comprehensive decongestive…

Podda M et al. · Trials · 30 out 2021

Nível de evidência 4 de 5

The Effects of Complete Decongestive Therapy or Intermittent Pneumatic Compression Therapy or Exercise Only in the Treatment of Severe Lipedema: A Randomized Controlled Trial

Background: Lack of diagnostic awareness of lipedema and frequent confusion with obesity or lymphedema may be an obstacle for treatment. The clinical effects of conservative treatment methods are not clearly known. This study…

Atan T, Bahar-Özdemir Y · Lymphatic research and biology · 9 dez 2020

Nível de evidência 4 de 5

Low-frequency vibrotherapy considerably improves the effectiveness of manual lymphatic drainage (MLD) in patients with lipedema: A two-armed, randomized, controlled pragmatic trial

Purpose: Although the exact prevalence of lipedema is unknown the number of women suffering from this condition is ever-growing. When treated conservatively, manual lymphatic drainage is regarded the gold standard. However, the…

Schneider R · Physiotherapy theory and practice · 30 mai 2018

Nível de evidência 4 de 5

Evaluation of patient-relevant outcomes of lymphedema and lipedema treatment: development and validation of a new benefit tool

Patient-relevant treatment benefit is traditionally measured with health-related quality of life (HRQoL) instruments. The Patient Benefit Index (PBI) methodology allows for a more direct measurement, with the patients rating both…

Blome C et al. · European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 22 out 2013