Diretrizes, consensos, metanálises, revisões sistemáticas e ensaios clínicos randomizados. 47 artigos.
This S2k guideline was developed on the initiative and under the German Society of Phlebology and Lymphology (DGPL) leadership. The guideline aims to optimize the diagnosis and treatment of lipedema. It is intended to bring…
Faerber G et al. · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 27 ago 2024
The COVID-19 pandemic poses a challenge to the management of non-COVID pathologies such as lymphatic diseases and lipoedema. The use of telemedicine can prevent the spread of the disease. A system is needed to help determine the…
Forner Cordero I et al. · Rehabilitacion · 8 ago 2020
Lipedema is a symmetrical disorder of the subcutaneous adipose tissue that affects almost exclusively women in postpubescent age. The trinity of disfiguring hyperplastic adipose tissue of the proximal extremities, increasing pain…
Wollina U, Heinig B · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 dez 2018
Lipedema is a symmetrical disorder of the subcutaneous adipose tissue that affects almost exclusively women in postpubescent age. The trinity of disfiguring hyperplastic adipose tissue of the proximal extremities, increasing pain…
Wollina U, Heinig B · Zeitschrift fur Rheumatologie · 1 nov 2018
Under the direction of the German Society of Phlebology (Deutsche Gesellschaft für Phlebologie) and in cooperation with other specialist associations, the S1 guideline on intermittent pneumatic compression (IPC) was adopted in…
Schwahn-Schreiber C et al. · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 ago 2018
Sem abstract disponível no PubMed.
Hardy D, Williams A · British journal of community nursing · 1 out 2017
The present, revised guidelines on lipedema were developed under the auspices of and funded by the German Society of Phlebology (DGP). The recommendations are based on a systematic literature search and the consensus of eight…
Reich-Schupke S et al. · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 1 jul 2017
Lymphedema results from impaired lymphatic transport with increased limb volume. Primary and secondary forms can be distinguished. Secondary lymphedema of the upper limb is the most frequent in France. A 2-cm difference on any…
Vignes S et al. · Journal des maladies vasculaires · 1 nov 2009
Background/Objectives: Non-invasive radiofrequency (NIRF) therapy is increasingly used in physical rehabilitation. However, its efficacy across different lower limb pathologies remains unclear. This study aimed to evaluate the…
Vinolo-Gil MJ et al. · Journal of clinical medicine · 22 mar 2026
Lipedema is a chronic disorder characterized by abnormal subcutaneous fat accumulation, mainly in women's lower limbs. The aim of the study was to analyze the safety and efficacy of liposuction in treating lipedema. A systematic…
Vengoechea JAA et al. · Aesthetic surgery journal. Open forum · 24 fev 2026
Lipoedema is a chronic, progressive condition characterised by disproportionate fat accumulation in the lower extremities, often misdiagnosed due to symptom overlap with obesity. Weight management is a key component of lipoedema…
Pajaziti Q et al. · Clinical obesity · 1 fev 2026
Dercum's disease (DD) is a rare connective tissue disorder characterized by multiple painful progressive adipose deposits. No definitive treatment for DD exists; therefore, the purpose of this study was to aggregate the current…
How-Volkman C et al. · Annals of plastic surgery · 28 jan 2026
Lipedema is a chronic disorder that affects the subcutaneous adipose tissue of the lower and upper limbs and results in painful fat accumulations. During the reproductive life span, about 11% of women are affected; however, there…
Lüchinger JE et al. · Archives of gynecology and obstetrics · 23 jan 2026
Lipedema is a chronic, underdiagnosed adipose disorder marked by disproportionate fat accumulation, pain, and impaired mobility. Misdiagnosis as obesity or lymphedema delays care and increases morbidity. We systematically…
Vazirnia A et al. · International journal of dermatology · 7 jan 2026
ObjectivesLipedema is a chronic condition that predominantly affects women, leading to painful, disproportionate fat distribution in the limbs. This systematic review and meta-analysis aimed to characterize health-related quality…
Günay UB, Talak GR, Demiröz A · Phlebology · 23 dez 2025
Lipedema is a chronic inflammatory disease characterized by symmetrical deposition of adipose tissue in the upper and lower limbs, disproportionate to the trunk. It primarily affects women. The objective of this study was to…
Coutinho ML et al. · Aesthetic plastic surgery · 14 dez 2025
Lipedema is a chronic, progressive disorder marked by the abnormal accumulation of subcutaneous adipose tissue, predominantly in the lower body and almost exclusively affecting women. In recent years, the off-label use of…
Amato AC, Amato JS, Benitti D · Cureus · 19 nov 2025
Lipedema is a chronic disease characterized by the disproportionate and symptomatic accumulation of fat in the lower limbs and arms. Women with lipedema experience heaviness, fatigue and pain, leading to impairments in daily…
Lanzi S et al. · VASA. Zeitschrift fur Gefasskrankheiten · 17 nov 2025
Lipedema is a chronic, progressive condition characterized by symmetrical accumulation of adipose tissue, predominantly in women's lower extremities. It is frequently associated with pain, reduced mobility, and psychological…
de Oliveira J, de Paula ACP, Guimarães VHD · Maturitas · 5 set 2025
Lipedema is a chronic and progressive disease that predominantly affects women, characterized by a disproportionate increase in subcutaneous adipose tissue (AT), particularly in the lower limbs. It is associated with significant…
Cifarelli V · Obesity reviews : an official journal of the International Association for the Study of Obesity · 27 mai 2025
To summarize the evidence of the immediate and long-term effect of exercise interventions in patients with either primary or secondary lower limb lymphedema (LLL) on health-related quality of life (HR-QOL), physical function,…
Wittenkamp MC et al. · Acta oncologica (Stockholm, Sweden) · 31 mar 2025
Carboxytherapy (CXT) is a minimally invasive procedure based on percutaneous or subcutaneous microinjections of carbon dioxide. Due to the Bohr effect, it influences the hemoglobin dissociation curve, improving tissue…
Susini P et al. · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 10 mar 2025
Lipedema diagnosis is heavily reliant on patient history. Various objective assessments have been suggested; however, a standardized measurement process is lacking. A systematic review was undertaken to identify which imaging and…
Eason HE et al. · Lymphatic research and biology · 5 mar 2025
Background: One of the main challenges in managing lymphedema and lipedema is the lack of valid and reliable objective measures for diagnosis and follow-up. This study was aimed at gathering evidence regarding the objective…
Vanaki A et al. · International journal of vascular medicine · 13 fev 2025
Lipedema is a frequently misdiagnosed condition in women, often mistaken for obesity, which significantly deteriorates both quality of life and physical health. Recognizing the necessity for holistic treatment strategies,…
Amato ACM, Amato JLS, Benitti DA · Nutrients · 27 set 2024
Lipedema is a relatively common, frequently misdiagnosed, chronic condition that is often treated using liposuction when conservative therapies fail. Techniques such as traditional tumescent liposuction (TTL), power-assisted…
Fijany AJ et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 31 jul 2024
Lipedema, a chronic and painful disorder primarily affecting women without a definitive cure, has traditionally been managed with conservative therapy, notably complete decongestive therapy, across many countries. Recently,…
Amato AC, Amato JL, Benitti D · Cureus · 29 fev 2024
Lipoedema is a symmetrically localised, painful hypertrophy of subcutaneous adipose tissue in the extremities with marked disproportion to the trunk, and almost exclusively affects females. Despite being first described over 80…
Funke S et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 20 nov 2023
Diagnosing lipedema remains a challenge due to its heterogeneous presentation, co-existing diseases, and the lack of objective diagnostic imaging. This systematic review aims to outline the currently available diagnostic imaging…
van la Parra RFD, Deconinck C, Krug B · Obesity reviews : an official journal of the International Association for the Study of Obesity · 3 out 2023
There are both conservative and surgical treatment options for lipohyperplasia dolorosa (LiDo). A procedure that has been established since 1997 is the surgical treatment through lymphological liposculpture according to Cornely™.…
Gensior M, Cornely M · Dermatologie (Heidelberg, Germany) · 9 nov 2022
When performing large volume liposuction, perioperative management of lipedema patients with coagulation disorders remains challenging due to a lack of clinical experience. With a prevalence of 1% of von Willebrand disease (VWD)…
Schmidt J et al. · Clinical hemorheology and microcirculation · 1 jan 2021
Regenerative therapies like cell-assisted lipotransfer or preclinical experimental studies use adipose tissue-derived stem cells (ASCs) as the main therapeutic agent. But there are also factors depending on the clinical donor…
Kuhlmann C et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 8 dez 2020
Introduction Lipedema is a chronic, progressive condition that can result in considerable disability. In 2011, the Dutch Society of Dermatology and Venereology organized a task force to create guidelines on lipedema, using the…
Halk AB, Damstra RJ · Phlebology · 9 jul 2016
Lipoedema is a painful, chronic disease of the subcutaneous adipose tissue, predominantly affecting women. Conservative complex decongestive therapy is the standard of care but offers limited symptom relief. Liposuction appears…
Podda M et al. · Lancet (London, England) · 5 set 2026
Lipedema is a chronic female disease characterized by a painful accumulation of adipose tissue in the limbs. Plasma fatty acid (FA) composition has been proposed as a potential modulator of pain. However, the pathophysiology…
Lundanes J et al. · Nutrition journal · 11 mar 2026
Background: Lipedema is a progressive disorder of subcutaneous connective tissue, predominantly affecting women, and characterized by an increase in subcutaneous adipose tissue, particularly in the lower body. This study aims to…
Di Renzo L et al. · Nutrients · 13 dez 2025
Background: Postoperative fibrosis is a common and significant complication following liposuction for lipedema, often leading to tissue induration, pain, and compromised aesthetic results. This fibrosis can jeopardize the overall…
Bruno A, Cilluffo M · Phlebology · 20 mai 2025
Objectives: This study aimed to examine the effects of a multimodal exercise program on edema, pain, exercise capacity, lower extremity muscle strength, and function in patients with lipedema.Methods: The patients diagnosed with…
Sakizli Erdal E et al. · Phlebology · 15 mai 2025
Ketosis seems to attenuate, or prevent, the rise in both ghrelin concentrations and subjective hunger ratings that follow weight loss. However, most of the previous studies have employed very-low energy diets (VLED) and are…
Lundanes J et al. · Clinical nutrition ESPEN · 19 nov 2024
The primary objective of this study was to evaluate the effect of a low-carbohydrate diet (LCD) compared with a control diet on pain in female patients with lipedema. The secondary objectives were to compare the impact of the two…
Lundanes J et al. · Obesity (Silver Spring, Md.) · 16 abr 2024
Background: Lymphedema and lipedema are debilitating conditions with no proven drug or surgical therapy. Effective treatment requires self-management through movement and compression to reduce limb volume and the incidence of…
Mortimer PS et al. · Lymphatic research and biology · 23 fev 2024
Does short-term use of pneumatic compression devices (PCD) and off-the-shelf compression alleviate symptoms and improve quality of life in women with lipedema and secondary lipolymphedema? Prospective, randomized controlled,…
Wright T, Scarfino CD, O'Malley EM · Phlebology · 15 dez 2022
Lipedema is a chronic disorder of the adipose tissue that affects mainly women, characterised by symmetrical, excessive fatty tissue on the legs and pain. Standard conservative treatment is long-term comprehensive decongestive…
Podda M et al. · Trials · 30 out 2021
Background: Lack of diagnostic awareness of lipedema and frequent confusion with obesity or lymphedema may be an obstacle for treatment. The clinical effects of conservative treatment methods are not clearly known. This study…
Atan T, Bahar-Özdemir Y · Lymphatic research and biology · 9 dez 2020
Purpose: Although the exact prevalence of lipedema is unknown the number of women suffering from this condition is ever-growing. When treated conservatively, manual lymphatic drainage is regarded the gold standard. However, the…
Schneider R · Physiotherapy theory and practice · 30 mai 2018
Patient-relevant treatment benefit is traditionally measured with health-related quality of life (HRQoL) instruments. The Patient Benefit Index (PBI) methodology allows for a more direct measurement, with the patients rating both…
Blome C et al. · European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 22 out 2013
Lipedema is a disproportional obesity for which evidence-based treatment is not currently available. We studied whether complete decongestive physiotherapy (CDP) alone or combined with intermittent pneumatic compression (IPC)…
Szolnoky G et al. · Lymphology · 1 mar 2008