Epidemiologia e clínica

Prevalência, coortes, comorbidades e diagnóstico diferencial. 154 artigos nesta área.

Maior nível de evidência

Objective Assessment of the Cardiorespiratory Fitness Among Individuals With Lymphedema and Lipedema: A Systematic Review and Meta-Analysis

Background: One of the main challenges in managing lymphedema and lipedema is the lack of valid and reliable objective measures for diagnosis and follow-up. This study was aimed at gathering evidence regarding the objective…

Vanaki A et al. · International journal of vascular medicine · 13 fev 2025

Nível de evidência 5 de 5

[Differential diagnostics of lipedema and lymphedema : A practical guideline]

Lipedema is a symmetrical disorder of the subcutaneous adipose tissue that affects almost exclusively women in postpubescent age. The trinity of disfiguring hyperplastic adipose tissue of the proximal extremities, increasing pain…

Wollina U, Heinig B · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 dez 2018

Todos, do mais recente ao mais antigo

Nível de evidência 3 de 5

Factors Associated with the Evolution in Quality of Life and Volume During the Maintenance Phase After a Multidisciplinary Intensive Treatment Program in Patients with Lower Limb Lymphedema

To evaluate which factors are associated with change in lymphedema-specific quality of life (QoL) and relative volume difference in the maintenance phase after a multidisciplinary intensive treatment program in patients with…

Heroes A et al. · Lymphatic research and biology · 22 out 2026

Nível de evidência 1 de 5

Cross-reactivity in cashew nut allergy

Cashew nut allergy is increasing globally and may cause cross-allergic reactions to seed kernels from botanically related plants, including citrus. A woman in her twenties with a known nut allergy developed anaphylaxis after…

Kahrs GE, Lied GA · Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke · 14 jul 2026

Nível de evidência 3 de 5

[Not Available]

Despite ongoing research, the prevalence of lipoedema still relies on estimates, with figures in the recent literature ranging from 1% to 10%. Large-scale epidemiological studies on lipoedema are lacking. This retrospective…

Aitzetmüller-Klietz M et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 12 mar 2026

Nível de evidência 2 de 5

Lipedema and obesity: A narrative review and treatment protocol

Lipedema is a chronic condition characterized by abnormal fat accumulation, primarily in the lower extremities, affecting mostly women. Despite improvements in diagnosis and treatment, lipedema is often misdiagnosed as obesity or…

Rathod S, Pouwels S, Schmidt J · JPRAS open · 19 jan 2026

Nível de evidência 3 de 5

Lipedema: Clinical Features, Diagnosis, and Management

Lipedema is an adipose tissue disorder that principally affects women and is frequently misidentified as obesity or lymphedema. There have been relatively few studies that have precisely defined the pathogenesis, epidemiology,…

Mortada H et al. · Archives of plastic surgery · 15 mai 2025

Nível de evidência 3 de 5

Building evidence for diagnosis of lipedema: using a classification and regression tree (CART) algorithm to differentiate lipedema from lymphedema patients

Discriminating lipedema from lymphedema becomes challenging in the absence of a pathognomonic test. The objective was to find the best manifestations that discriminate between lipedema and lymphedema and to build a diagnosis…

Forner-Cordero I, Muñoz-Langa J, Morilla-Bellido L · International angiology : a journal of the International Union of Angiology · 26 fev 2025

Objective Assessment of the Cardiorespiratory Fitness Among Individuals With Lymphedema and Lipedema: A Systematic Review and Meta-Analysis

Background: One of the main challenges in managing lymphedema and lipedema is the lack of valid and reliable objective measures for diagnosis and follow-up. This study was aimed at gathering evidence regarding the objective…

Vanaki A et al. · International journal of vascular medicine · 13 fev 2025

Nível de evidência 3 de 5

Is lipedema a progressive disease?

It is not yet known whether lipedema is a progressive chronic disease or not. The aim of this paper is to describe the long-term changes in the volume of the lower limbs. The primary endpoint of this prospective cohort study of…

Forner-Cordero I, Muñoz-Langa J · Vascular medicine (London, England) · 20 jan 2025

Nível de evidência 1 de 5

Comments on: Comparison of fluid and body composition measures in women with lipoedema, lymphoedema, and control participants

Recently, we read with interest the article 'Comparison of fluid and body composition measures in women with lipoedema, lymphoedema, and control participants' by Stellmaker R, Thompson B, Mackie H, Koelmeyer L. Clin Obes.…

Pereira de Godoy HJ, Pereira de Godoy JM · Clinical obesity · 27 out 2024

Nível de evidência 2 de 5

Lymphedema vs lipedema: Similar but different

Lymphedema and lipedema are chronic debilitating disorders that most commonly affect the upper and lower extremities. Although they can appear similar, they differ in important ways, which the authors of this article review and…

Lomeli LD et al. · Cleveland Clinic journal of medicine · 1 jul 2024

Nível de evidência 3 de 5

National Lymphoedema Conference 2024: session summaries

The 11th annual National Lymphoedema Conference, organised by the British Journal of Community Nursing in association with the British Lymphology Society and Lipoedema UK, was hosted at the America Square Conference Centre,…

Hashimi S, Rajagopalan U · British journal of community nursing · 1 abr 2024

Nível de evidência 2 de 5

Proposed Framework for Research Case Definitions of Lipedema

Background: Our aim is to propose a framework for the development of a research case definition of lipedema, based on current available literature and those observations that can be applied to future lipedema research with the…

Keith L et al. · Lymphatic research and biology · 28 mar 2024

Nível de evidência 3 de 5

Observational Study on a Large Italian Population with Lipedema: Biochemical and Hormonal Profile, Anatomical and Clinical Evaluation, Self-Reported History

We analyzed the medical condition of 360 women affected by lipedema of the lower limbs in stages 1, 2, and 3. The data were assessed for the whole population and compared between different clinical stages, distinguishing between…

Patton L et al. · International journal of molecular sciences · 27 jan 2024

Nível de evidência 3 de 5

Obesity, thrombosis, venous disease, lymphatic disease, and lipedema: An obesity medicine association (OMA) clinical practice statement (CPS) 2023

This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) is intended to provide clinicians with an overview on obesity, thrombosis, venous disease, lymphatic disease, and lipedema. The scientific support for this…

Bindlish S et al. · Obesity pillars · 19 out 2023

Nível de evidência 3 de 5

Effect of Physical Therapy on Circumference Measurement and Extremity Volume in Patients Suffering from Lipedema with Secondary Lymphedema

Background: Lipedema is a chronic and progressive disease. Many complications can occur if the disease is not treated. The most important of these complications is lipedema with secondary lymphedema. There are very few…

Esmer M, Schingale FJ · Lymphatic research and biology · 3 out 2023

Nível de evidência 3 de 5

Body mass index vs. waist-to-height-ratio in patients with lipohyperplasia dolorosa (vulgo lipedema)

Lipedema, also known as lipohyperplasia dolorosa (LiDo), is a painful condition affecting women, causing a disproportionate accumulation of subcutaneous adipose tissue in the extremities. It carries a lower risk of diabetes and…

Brenner E et al. · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 30 ago 2023

Nível de evidência 3 de 5

Frequency of lipoedema in patients consulting a vein clinic for mild to moderate superficial venous disorder with symptoms: A retrospective analysis

Lower limb lipoedema is a chronic condition of the adipose connective tissue of the skin that affects women. Its frequency is not well known, hence the main objective of this study. Retrospective analysis of the records of…

Rastel D, Urbinelli R · Journal de medecine vasculaire · 24 jun 2023

Nível de evidência 2 de 5

Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium

Enhancing our understanding of lymphatic anatomy from the microscopic to the anatomical scale is essential to discern how the structure and function of the lymphatic system interacts with different tissues and organs within the…

Singhal D et al. · Frontiers in physiology · 6 fev 2023

Nível de evidência 3 de 5

Diagnostic Comparability of Ratio of Tissue Dielectric Constant (TDC) Between Patients with Lipedema and Those with Lower Limb Lymphedema (LLL): A Prospective Observational Study

Lipedema is usually thought of as a dis-ease of women. Potentially diagnostic comparative data is needed between patients with lip-edema and those with lower limb lymphedema (LLL). Since there is no gold standard to diagnose…

Tugral A, Bakar Y · Lymphology · 1 jan 2023

Nível de evidência 3 de 5

Lymphatic function and anatomy in early stages of lipedema

Lipedema is an inflammatory subcutaneous adipose tissue disease that develops in women and may progress to lipolymphedema, a condition similar to lymphedema, in which lymphatic dysfunction results in irresolvable edema. Because…

Rasmussen JC et al. · Obesity (Silver Spring, Md.) · 15 jun 2022

Nível de evidência 3 de 5

Lipedema prevalence and risk factors in Brazil

Lipedema is characterized as an abnormal deposition of fat in the buttocks and legs bilaterally that may be accompanied by swelling, pain, and tenderness. It is still often confused with more frequent conditions such as obesity…

Amato ACM et al. · Jornal vascular brasileiro · 23 mai 2022

Nível de evidência 3 de 5

What do lymphedema patients expect from a treatment and what do they achieve? A descriptive study

Lymphedema is characterized by swelling and fibroadipose tissue deposition that is a physically, psychologically, and socially debilitating condition due to chronic and progressive nature of the disease. Treatment benefit…

Duygu Yildiz E, Bakar Y, Keser I · Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing · 26 jan 2022

Nível de evidência 1 de 5

Regression of lipoedematous scalp following cryolipolysis using an icepack, with a novel dermoscopic feature of yellow background

The novel use of cryolipolysis via icepacks, a readily available and inexpensive device, is described for lipoedematous scalp with subjective and objective relief. This is a simple solution to a troublesome, intractable condition…

Kharkar V, Vishwanath T, Kamble P · Clinical and experimental dermatology · 12 out 2021

Nível de evidência 3 de 5

Women's experiences of living with lipedema

Lipedema is a chronic, progressive disease that almost exclusively affects women and often misdiagnosed as obesity or primary lymphedema. Research concerning lipedema is sparse, and there is a lack of studies focusing on women's…

Melander C, Juuso P, Olsson M · Health care for women international · 12 jul 2021

Nível de evidência 3 de 5

Standard of care for lipedema in the United States

Lipedema is a loose connective tissue disease predominantly in women identified by increased nodular and fibrotic adipose tissue on the buttocks, hips and limbs that develops at times of hormone, weight and shape change including…

Herbst KL et al. · Phlebology · 28 mai 2021

Nível de evidência 3 de 5

[Lipedema : an unknown entity]

Lipedema is an infrequently recognized disorder. It is characterized by bilateral painful enlargement of the legs due to abnormal depositions of subcutaneous fat, that can result in considerable disability. The diagnosis is…

Naef V, Alvarez Martinez D, Cortes B · Revue medicale suisse · 31 mar 2021

Nível de evidência 3 de 5

Interstitial Fluid in Lipedema and Control Skin

Background: Fluid in lymphedema tissue appears histologically as spaces around vessels and between dermal skin fibers. Lipedema is a painful disease of excess loose connective tissue (fat) in limbs, almost exclusively of women,…

Allen M, Schwartz M, Herbst KL · Women's health reports (New Rochelle, N.Y.) · 14 out 2020

Nível de evidência 3 de 5

Cross-sectional validity and specificity of comprehensive measurement in lymphedema and lipedema of the lower extremity: a comparison of five outcome instruments

Literature on the validity of outcome measurement in lymphedema and lipedema is very sparse. This study aimed to examine the convergent, divergent and discriminant validity of a set of 5 instruments in both conditions.…

Angst F et al. · Health and quality of life outcomes · 22 jul 2020

Nível de evidência 3 de 5

Characterizing Lower Extremity Lymphedema and Lipedema with Cutaneous Ultrasonography and an Objective Computer-Assisted Measurement of Dermal Echogenicity

Background: Sonographic findings differ in patients with primary lipedema from those with lymphedema. This project was designed to quantify those differences and objectively characterize findings of lipedema and lymphedema in the…

Iker E et al. · Lymphatic research and biology · 7 jan 2019

Nível de evidência 1 de 5

[Lymphedema complicated with verrucous papillomatosis]

Limb lymphedemas are due to a malfunction of the lymphatic system responsible for lymph stasis in the interstitial tissue and secondarily to an increase in the volume of the affected limb. They are divided into primary lymphedema…

Agharbi F · The Pan African medical journal · 28 dez 2018

Nível de evidência 2 de 5

Lipedema-An update

Lipedema is a chronic disabilitating disease affecting the subcutaneous adipose tissue of the extremities in females during or after puberty. The disease is characterized by bilateral swelling of legs and/or arms, bruising, and…

Wollina U · Dermatologic therapy · 27 dez 2018

Nível de evidência 5 de 5

[Differential diagnostics of lipedema and lymphedema : A practical guideline]

Lipedema is a symmetrical disorder of the subcutaneous adipose tissue that affects almost exclusively women in postpubescent age. The trinity of disfiguring hyperplastic adipose tissue of the proximal extremities, increasing pain…

Wollina U, Heinig B · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 dez 2018

Nível de evidência 2 de 5

Lipedema: friend and foe

Background Lipedema is a chronic disorder presenting in women during puberty or other times of hormonal change such as childbirth or menopause, characterized by symmetric enlargement of nodular, painful subcutaneous adipose…

Torre YSl et al. · Hormone molecular biology and clinical investigation · 9 mar 2018

Nível de evidência 3 de 5

Left ventricular rotational mechanics differ between lipedema and lymphedema: Insights from the three-dimensional speckle tracking echocardiographic MAGYAR-path study

The present study aimed to assess LV rotational mechanics by three-dimensional speckle-tracking echocardiography (3DSTE) in lipedema (n=25), lymphedema (n=26) patient groups with age- and gender-matched healthy controls (n=54). 3…

Nemes A et al. · Lymphology · 1 jan 2018

Nível de evidência 2 de 5

Lipedema

Sem abstract disponível no PubMed.

Canning C, Bartholomew JR · Vascular medicine (London, England) · 16 nov 2017

Nível de evidência 3 de 5

Quality of life in patients with primary and secondary lymphedema in the community

Lymphedema is a complex and burdensome medical problem and requires continuous specific therapy. The aim of this cross-sectional study of community lymphedema care in the metropolitan area of Hamburg, Germany, was to evaluate…

Herberger K et al. · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 27 abr 2017

Nível de evidência 2 de 5

[Lymphedema: From diagnosis to treatment]

Lymphedema results from impaired lymphatic transport with increased limb volume. Lymphedema are divided in primary and secondary forms. Upper-limb lymphedema secondary to breast cancer treatment is the most frequent in France.…

Vignes S · La Revue de medecine interne · 31 ago 2016

Nível de evidência 2 de 5

Lipedema: A Review of the Literature

Lipedema is a disorder of adipose tissue that primarily affects females and is often misdiagnosed as obesity or lymphedema. Relatively few studies have defined the precise pathogenesis, epidemiology, and management strategies for…

Okhovat J, Alavi A · The international journal of lower extremity wounds · 17 out 2014

Nível de evidência 1 de 5

Is lymphostasis an aggravant of lipedema?

A 54-year-old female patient reported that a characteristic of her family was 'fat legs' with postural edema since adolescence. Over the years the patient had been gaining weight with an increase in fatty tissue in the legs and…

Godoy MdFG et al. · Case reports in dermatology · 23 out 2012

Nível de evidência 1 de 5

Progressive lipo-lymphedema associated with increased activity of dermal fibroblasts in monoclonal gammopathy of undetermined significance: is there a causal relationship?

The pathophysiology of skin diseases associated with monoclonal gammopathies is generally unknown. Our aim was to investigate whether a monoclonal gammopathy could be a causal factor in progressive lymphedema. We describe a 75…

Thielitz A et al. · Lymphology · 1 set 2012

Nível de evidência 2 de 5

Rare adipose disorders (RADs) masquerading as obesity

Rare adipose disorders (RADs) including multiple symmetric lipomatosis (MSL), lipedema and Dercum's disease (DD) may be misdiagnosed as obesity. Lifestyle changes, such as reduced caloric intake and increased physical activity…

Herbst KL · Acta pharmacologica Sinica · 1 fev 2012

Nível de evidência 1 de 5

Clinical aspects of advanced stage lipo-lymphedema: case report

The aim of the current study was to alert about dermatological alterations in the clinical evolution of lipo-lymphedema. The case of a 48-year-old patient is reported with clinical diagnosis of stage II lipo-lymphedema treated in…

Pereira De Godoy JM et al. · Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia · 1 ago 2010

Nível de evidência 3 de 5

Lipedema: an inherited condition

Lipedema is a condition characterized by swelling and enlargement of the lower limbs due to abnormal deposition of subcutaneous fat. Lipedema is an under-recognized condition, often misdiagnosed as lymphedema or dismissed as…

Child AH et al. · American journal of medical genetics. Part A · 1 abr 2010

Nível de evidência 2 de 5

The clinical spectrum of lymphatic disease

Lymphatic disease is quite prevalent, and often not well clinically characterized. Beyond lymphedema, there is a broad array of human disease that directly or indirectly alters lymphatic structure and function. The symptomatic…

Radhakrishnan K, Rockson SG · Annals of the New York Academy of Sciences · 1 jan 2008

Nível de evidência 2 de 5

[Lipoedema]

Sem abstract disponível no PubMed.

Vignes S · Annales de dermatologie et de venereologie · 1 jan 2006

Nível de evidência 1 de 5

Kaposi sarcoma associated with lipoedema

Lipoedema is a form of lipodistrophy, which consists of abnormal accumulation of fat in subcutaneous tissue of the lower limbs. It does not cause any disease and it has not been reported association with malignity. We describe a…

Ekmekci TR et al. · Journal of the European Academy of Dermatology and Venereology : JEADV · 1 mai 2005

Nível de evidência 1 de 5

[Lipedema complicated with lymphedema and chyloderma]

Lipedema never reveals clinical picture of extreme lymphedema-elephantiasis, and skin signs and complications have not been observed. Aim of this paper is to present a case of lipedema with the initial lymphedema in which, after…

Ignjatović M, Jevtić M, Cerović S · Vojnosanitetski pregled · 1 jan 2000

Nível de evidência 3 de 5

Lipedema: a clinical entity distinct from lymphedema

In a review of 250 cases of lymphedema of the lower extremity, 9 patients were noted to share unique similarities in their history and physical findings. Although these patients had mild swelling in their pretibial areas and were…

Rudkin GH, Miller TA · Plastic and reconstructive surgery · 1 nov 1994

Nível de evidência 2 de 5

Microlymphatics of human skin

Microlymphatics of human skin form two superposed networks. The superficial one located at the level of dermal papillae may be visualized by fluorescence microlymphography. Microlymphatics fill from a subepidermal depot of minute…

Bollinger A · International journal of microcirculation, clinical and experimental · 1 fev 1993

Nível de evidência 3 de 5

[Lipedema]

Sem abstract disponível no PubMed.

Gregl A · Zeitschrift fur Lymphologie. Journal of lymphology · 1 dez 1987