Estudo original

485 artigos deste tipo, do mais recente ao mais antigo.

Nível de evidência 3 de 5

LipoVena AI framework: A physician-centered artificial intelligence-assisted approach for longitudinal assessment in lipedema and chronic venous disorders

BackgroundChronic venous disorders and lipedema are complex and frequently underdiagnosed conditions characterized by heterogeneous clinical presentations, progressive tissue remodeling, and substantial variability in treatment…

Hendesi F, Nazem A · Phlebology · 23 out 2026

Nível de evidência 3 de 5

Factors Associated with the Evolution in Quality of Life and Volume During the Maintenance Phase After a Multidisciplinary Intensive Treatment Program in Patients with Lower Limb Lymphedema

To evaluate which factors are associated with change in lymphedema-specific quality of life (QoL) and relative volume difference in the maintenance phase after a multidisciplinary intensive treatment program in patients with…

Heroes A et al. · Lymphatic research and biology · 22 out 2026

Nível de evidência 3 de 5

Lipedema research (2000-2025): a global bibliometric analysis with evidence of an emerging immunological paradigm

The aim of this study was to characterize global scientific output on lipedema from 2000 to 2025 and identify emerging thematic trends, with emphasis on the emergence of immunological research. Publications indexed in Google…

Amato ACM, Amato JLS, Benitti DA · Revista da Associacao Medica Brasileira (1992) · 16 out 2026

Nível de evidência 3 de 5

Venous reflux and CEAP clinical class in patients with lipedema: Prevalence, duplex ultrasonographic patterns, and clinical associations

ObjectivesTo determine the prevalence of chronic venous insufficiency (CVI) in patients with lipedema, characterize venous reflux patterns and CEAP clinical classes, and evaluate associations with demographic and lipedema-related…

Gümrük Aslan S, Akın Yavuzel A, Gündoğdu O · Phlebology · 15 out 2026

Nível de evidência 3 de 5

Screening for lipedema in women with lower extremity pain and its associations with functional status, pain, mood, and quality of life: A questionnaire-based case-control study

ObjectivesThis study aimed to determine the frequency of probable lipedema among women with lower extremity pain (LEP) using a validated screening questionnaire and to examine its associations with neuropathic pain (NP)…

Demir Karakılıç G et al. · Phlebology · 8 out 2026

Nível de evidência 3 de 5

Manual lymphatic drainage reduces tissue sodium and self-reported pain in women with lipedema: a quantitative MRI study

Lipedema is a chronic adipose tissue disorder characterized by a disproportionate accumulation of painful subcutaneous fat on the extremities. Manual lymphatic drainage (MLD) is routinely used as therapeutic intervention, but its…

Nöll E et al. · Frontiers in cell and developmental biology · 7 out 2026

Nível de evidência 3 de 5

Orthorexic Eating Tendencies and Body Shape Concern in Women with Lipedema: A Controlled Cross-Sectional Study

Background/Objectives: Lipedema is an adipose tissue disorder associated with body-related burden. This study compared orthorexic eating tendencies between women with and without lipedema and examined associations with body-shape…

Doran M, Zincirci DE, Şahan EG · Journal of clinical medicine · 4 out 2026

Nível de evidência 3 de 5

Evaluation of Serum Irisin, Leptin, Adiponectin, Resistin, and Galectin-3 Levels and Their Relationship with Ultrasonographic Subcutaneous Fat Thickness in Patients with Lipedema

The aim of this study was to compare serum adiponectin, leptin, resistin, irisin, and galectin-3 levels between patients with lipedema and healthy controls, and to examine their relationship with subcutaneous adipose tissue…

Şahingöz Bakırcı E, Demir Karakılıç G, Kaymak E · Aesthetic plastic surgery · 28 set 2026

Nível de evidência 3 de 5

Multidimensional Comparative Effectiveness of Extracorporeal Shock Wave Therapy and Complex Decongestive Therapy in Lipedema: A Randomized Controlled Trial

To compare the efficacies of extracorporeal shock wave therapy (ESWT) and complex decongestive therapy (CDT) in patients with lipedema. This randomized-controlled-study included 33 patients with lipedema, with 11 patients in each…

Türköz MD, Kasap Z, Keleş B · American journal of physical medicine & rehabilitation · 24 set 2026

Nível de evidência 3 de 5

Body Composition Changes With Standard Versus Low-Dose Tirzepatide Titration in Women With Lipedema: A Retrospective Observational Study

This study aimed to compare 12-week changes in body composition and anthropometric parameters between standard-dose and lower-dose tirzepatide escalation regimens in women with lipedema, with particular emphasis on changes in fat…

Frederichi de Souza P, Patriani G, Ribeiro Pacheco CM · Cureus · 23 set 2026

Nível de evidência 3 de 5

Are anamnesis, examination and/or technical investigations of the skin and subcutaneous adipose tissue able to discriminate between lipedema and women without leg affections?

IntroductionAfter unification of diagnostic criteria for lipedema through guidelines and consensus documents as a fat-disproportion between abdomen and extremities with pain in the affected area, reduced by compression, expensive…

Mendoza E, Amsler F · Phlebology · 21 set 2026

Nível de evidência 3 de 5

A qualitative study exploring the experiences of individuals living with lipoedema and the impacts it has on their quality of life

Individuals with lipoedema may experience negative impacts that are not often identified through current quality-of-life measures. The aim of this study was to explore the experiences of individuals living with pre-existing…

Stellmaker R et al. · International journal of qualitative studies on health and well-being · 18 set 2026

Nível de evidência 3 de 5

Anatomofunctional Zone-Based Marking of the Lower Limbs (Angioderma Leg Mapping): A Proposed Standardized Methodology for Therapeutic Planning

The aesthetic-functional planning of the lower limbs is frequently conducted empirically, using idiosyncratic markings and limited standardization among specialists who work in this field. The absence of a common topographic…

Zeilmann E, Mello Netto BAS, Santos GS · Cureus · 12 set 2026

Nível de evidência 3 de 5

A Multidimensional Assessment of Central Sensitization and Pain in Lipedema: Associations with Sleep and Quality of Life in a Case-Control Study

To comprehensively characterize pain in women with lipedema and evaluate its relationship with central sensitization, neuropathic pain characteristics, pain sensitivity, sleep quality, and quality of life. : A cross-sectional…

Orhan B et al. · Pain medicine (Malden, Mass.) · 12 set 2026

Nível de evidência 3 de 5

Central sensitization and pressure pain threshold in lipedema: Associations with clinical features, sonographic fat thickness, and body composition

ObjectiveThis study aimed to investigate central sensitization (CS) in individuals with lipedema using pressure pain threshold measurements and to examine its relationship with clinical features, sonographic findings, body…

Yücel FN, Candan Z, Ata E · Phlebology · 18 ago 2026

Nível de evidência 3 de 5

Lipedema in Sweden - "The LISE-study": Quality of life and body image in women with lipedema compared to healthy controls and women with cancer

Women with lipedema have an abnormal accumulation of adipose tissue that leads to pain and reduced quality of life (QoL). The impact of lipedema on body image and QoL remains largely unknown. The aim of this study is to explore…

Goodrose-Flores C, Björkhem-Bergman L · PloS one · 14 ago 2026

Nível de evidência 3 de 5

Association between pain, body mass index, and clinical characteristics in lipedema: Segmental analysis using bioimpedance

We aimed to evaluate the association between pain, body mass index (BMI), clinical stage, and morphological type in women with lipedema, using segmental bioimpedance to correlate with clinical symptoms. We conducted a…

Pusic J, Mora S, Froes Meyer P · Journal of vascular surgery. Venous and lymphatic disorders · 24 jul 2026

Nível de evidência 3 de 5

Inflammatory Profile of Lipedema: A Comparative Evaluation with Obese and Normal-Weight Women

Lipedema is a chronic disorder characterized by disproportionate subcutaneous fat accumulation and pain, with an incompletely understood inflammatory component. It remains unclear whether this inflammatory profile is…

Şahingöz Bakırcı E, Demir Karakılıç G · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 30 jun 2026

Nível de evidência 3 de 5

Are Routine Labs Necessary? Postoperative Electrolyte Trends in Lipedema Patients Undergoing Liposuction: Insights from a Single-Center Retrospective Cohort

Liposuction is a standard treatment for advanced-stage lipedema, often involving large volumes of tumescent fluid infiltration and aspiration. These shifts raise concerns about postoperative electrolyte imbalances, though…

Witulski C et al. · Aesthetic plastic surgery · 30 jun 2026

Nível de evidência 3 de 5

Exploring quality of life and physical-physiological characteristics in obese patients with and without lipedema: insights from the LipObes study

Lipedema is a prevalent chronic condition in women, characterized by a painful and symmetrical accumulation of adipose tissue primarily in the lower limbs. Its diagnosis is based on specific clinical characteristics; however,…

Gursen C et al. · BMC women's health · 20 jun 2026

Nível de evidência 3 de 5

Artificial intelligence in the management of chronic pain and lipedema: A comparative analysis of ChatGPT-5o, Gemini-3, and perplexity AI in terms of readability and academic reliability

ObjectivesLipedema is a chronic disorder characterized by pain and disproportionate fat distribution, and its diagnosis is frequently overlooked. The aim of this study was to evaluate and compare the responses generated by…

Özbek İC, Özduran E · Phlebology · 9 jun 2026

Nível de evidência 3 de 5

Inflammatory Markers in Lipedema: A Comparative Analysis of Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Mean Platelet Volume

BACKGROUND/AIM: Although various distinctive morphological features such as hyperproliferation of adipocytes, fibrosis, and inflammation have been described in the progression of lipedema, the underlying mechanisms of these…

Cagliyan Turk A, Erden E, Borman P · Lymphatic research and biology · 9 jun 2026

Nível de evidência 3 de 5

Clinical, ultrasound, elastography and bioimpedance changes after radial extracorporeal shock wave therapy in patients with lipedema: A prospective within-patient study

BackgroundLipedema is an adipose disorder associated with multiple impairments. Conservative treatments remain the mainstay of management, yet evidence regarding the effects of physical therapies on clinical, imaging, and body…

Novo Rigueiro M et al. · Phlebology · 11 mai 2026

Nível de evidência 3 de 5

Changes in Vascular, Lymphatic, Inflammatory, and Lipid Mediators During a 7-Month Calorie-Restricted Low-Carbohydrate, High-Fat Dietary Intervention in Women with Lipedema: A Preliminary Prospective Study

Background/Objectives: Lipedema is a chronic adipose tissue disorder characterized by disproportionate fat accumulation, pain, microvascular dysfunction, and low-grade inflammation. Although low-carbohydrate, high-fat (LCHF)…

Chachaj A et al. · Nutrients · 28 abr 2026

Nível de evidência 3 de 5

Assessment of the elasticity of lipedematous tissue and the examination of the relationship between pain and fibrosis in lipedema

BACKGROUND/OBJECTIVES: Lipedema is a chronic and progressive adipose tissue disorder characterized by the abnormal accumulation of subcutaneous fat, predominantly in the legs and occasionally in the arms. The symptom that most…

Yaman A, Mansız-Kaplan B · International journal of obesity (2005) · 14 mar 2026

Nível de evidência 3 de 5

[Not Available]

Despite ongoing research, the prevalence of lipoedema still relies on estimates, with figures in the recent literature ranging from 1% to 10%. Large-scale epidemiological studies on lipoedema are lacking. This retrospective…

Aitzetmüller-Klietz M et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 12 mar 2026

Nível de evidência 3 de 5

Exploring the Immunological Shield Hypothesis: A Population-Based Exploration of Phenotypic Divergence Between Lipedema and Celiac Disease Autoimmunity

Background Lipedema is characterized by disproportionate gluteofemoral adiposity with anti-inflammatory properties. We hypothesized that this phenotype may confer immunological protection against T-helper 1 (Th1)-mediated…

Amato AC, Amato JL, Benitti D · Cureus · 25 fev 2026

Nível de evidência 3 de 5

Macroscopic fat embolism after liposuction

Liposuction is the most frequently performed aesthetic surgical procedure on women worldwide. Thromboembolic events and fat embolisms are rare but typical complications of the procedure. To understand the associated risk factors,…

Edler C et al. · Forensic science, medicine, and pathology · 14 fev 2026

Nível de evidência 3 de 5

A multidimensional evaluation of pain in lipedema

ObjectivesThis study aimed to analyze the complex components of pain in lipedema and to evaluate correlations among key pain-related parameters, including intensity, hypersensitivity, catastrophizing, central sensitization, and…

Sakizli Erdal E et al. · Phlebology · 13 fev 2026

Nível de evidência 3 de 5

A retrospective cross-sectional study comparing health-related quality-of-life in females with lipoedema and bilateral leg lymphoedema

Lipoedema is a condition of abnormal accumulation of painful adipose tissue, usually in the lower body of women. The disproportionate subcutaneous adipose tissue may negatively impact health-related quality of life (HRQoL). There…

Stellmaker R et al. · Journal of psychosomatic research · 2 fev 2026

Nível de evidência 3 de 5

Epigenetic alterations of AKT1 orchestrate a metabolic reprogramming in advanced lipedema: translational insights from an integrated multi-omics study

lipedema is a chronic, progressive adipose disorder predominantly affecting women, characterized by painful, symmetrical subcutaneous fat accumulation, and typically resistant to lifestyle interventions. The pathophysiology of…

Santella B et al. · Journal of translational medicine · 24 jan 2026

Nível de evidência 3 de 5

Lipedema World Alliance Delphi Consensus-Based Position Paper on the Definition and Management of Lipedema: Results from the 2023 Lipedema World Congress in Potsdam

Lipedema predominantly affects women and is characterized by an abnormal distribution of adipose tissue, accompanied by pain or discomfort in affected areas. Despite growing awareness, inconsistent diagnostic criteria and…

Kruppa P et al. · Nature communications · 10 jan 2026

Nível de evidência 3 de 5

A single center retrospective observational study on 106 consecutive lipedema surgeries: Defining the ideal surgical approach

Lipedema causes abnormal fat accumulation in the limbs, leading to pain, functional impairment, and body image disturbance. Nowadays, various liposuction techniques are available. The wet technique is increasingly being…

Thiry M et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 23 dez 2025

Nível de evidência 3 de 5

Effects of lipedema on lower limb muscle strength, muscle endurance, functionality, functional exercise capacity, pressure pain threshold and edema: A case-control study

Lipedema is an abnormal accumulation of subcutaneous fat that usually affects the lower extremities. Inflammation due to adipose tissue may negatively affect body structure and functions. This case-control study aimed to assess…

Haspolat M et al. · Physiotherapy theory and practice · 28 nov 2025

Nível de evidência 3 de 5

Dietary Inflammatory Index and Mediterranean Diet Score are associated with systemic inflammation in women with lipedema

BACKGROUND/OBJECTIVES: Lipedema is a chronic adipose tissue disorder characterized by disproportionate fat accumulation, pain, and low-grade systemic inflammation, primarily affecting women. This study investigated the…

Tel Adıgüzel K et al. · International journal of obesity (2005) · 27 nov 2025

Nível de evidência 3 de 5

Clinical effects of TECAR therapy in the conservative management of Stage 2 lipedema in females: A randomized controlled trial

This study aimed to evaluate the clinical efficacy of transfer energy capacitive and resistive (TECAR) therapy in females with Stage 2 lipedema, focusing on limb circumference, pain, functional status, and quality of life. A…

Uzun Ö et al. · Turkish journal of physical medicine and rehabilitation · 10 nov 2025

Nível de evidência 3 de 5

Quantifying Morphological Change in Stage III Lipedema: A 3D Imaging Study of Population Trends and Individual Treatment Courses

Background/Objectives: Lipedema is a chronic disorder characterized by disproportionate fat accumulation in the extremities, causing pain, bruising, and reduced mobility. When conservative therapy fails, liposuction is considered…

Sanktjohanser NA et al. · Journal of personalized medicine · 1 nov 2025

Nível de evidência 3 de 5

[Results and limitations in surgery for Lipedema, Lymphedema and Elephantiasis of the lower limbs in a resource-limited country: Democratic Republic of Congo, 2010 to 2025]

This study aims to present the results and limitations of surgery for lower limb lipoedema and lymphedema in a resource-limited surgical setting. This was a cross-sectional, analytical, prospective, in-hospital study covering 15…

Kibadi-Kapay A · The Pan African medical journal · 30 out 2025

Nível de evidência 3 de 5

Development of an Evidence-Based and Theory-Informed Self-Management Intervention for People with Lipoedema: An Intervention Mapping Study

The etiology of lipoedema remains unclear, making diagnosis and treatment challenging. Current treatment primarily consists of general lifestyle recommendations, with effective self-management being essential for integrating…

Kloosterman LM et al. · Journal of multidisciplinary healthcare · 26 set 2025

Nível de evidência 3 de 5

Relationship of the tissue stiffness measured using shear wave elastography with the pain threshold and quality of life of patients with lipedema: A cross-sectional study

ObjectiveTo assess the relationship between disease severity in lipedema and tissue stiffness measured using shear wave elastography (SWE) concerning pain threshold and quality of life as well as determine differences in…

Ozturk G et al. · Phlebology · 16 jul 2025

Nível de evidência 3 de 5

Selective combined liposuction (SCL) for lipedema treatment: Outcomes in symptoms improvement and aesthetic self-perception

Lipedema is a chronic, progressive and underdiagnosed condition characterized by bilateral, disproportionate and painful subcutaneous fat accumulation in extremities. Key symptoms include pain, heaviness and easy bruising.…

Pereira N et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 3 jul 2025

Nível de evidência 3 de 5

Lipedema: Clinical Features, Diagnosis, and Management

Lipedema is an adipose tissue disorder that principally affects women and is frequently misidentified as obesity or lymphedema. There have been relatively few studies that have precisely defined the pathogenesis, epidemiology,…

Mortada H et al. · Archives of plastic surgery · 15 mai 2025

Nível de evidência 3 de 5

An Advanced Pneumatic Compression Therapy System Improves Leg Volume and Fluid, Adipose Tissue Thickness, Symptoms, and Quality of Life and Reduces Risk of Lymphedema in Women with Lipedema

Lipedema is a painful disease of subcutaneous adipose tissue (SAT) in women. This study determined whether an advanced pneumatic compression device (APCD) improved lipedema SAT depth, swelling, and pain. Women with lipedema…

Herbst KL et al. · Life (Basel, Switzerland) · 30 abr 2025

Nível de evidência 3 de 5

[Health-related quality of life and psychological abnormalities in patients with lipedema compared to healthy and chronically ill populations]

Lipedema is a chronical progressive disease mostly found in women, characterized by an unproportional increase of fat in the limbs and pain. So far mental perspectives are not acceptably resolved. This study examines patients'…

Kreidel Y et al. · Psychotherapie, Psychosomatik, medizinische Psychologie · 3 abr 2025

Nível de evidência 3 de 5

The Comparative Evaluation of Depression, Life Satisfaction, and Quality of Life Between Female Patients with Lipedema and Lymphedema

Introduction: Lymphedema and lipedema are chronic conditions significantly impacting psychosocial status and quality of life (QOL). However, comparative studies on depression, life satisfaction, functional status, and QoL in…

Yaman A et al. · Lymphatic research and biology · 13 mar 2025

Nível de evidência 3 de 5

Comprehensive Needs Assessment for Enhancing Self-Management in People with Lipoedema and the Support Provided by Their Healthcare Professionals

The cause of lipoedema remains unclear, and the condition is currently incurable. Effective self-management is therefore essential for coping with its physical and psychological impacts and the necessary lifestyle adjustments.…

Kloosterman LM et al. · Journal of multidisciplinary healthcare · 27 fev 2025

Nível de evidência 3 de 5

Building evidence for diagnosis of lipedema: using a classification and regression tree (CART) algorithm to differentiate lipedema from lymphedema patients

Discriminating lipedema from lymphedema becomes challenging in the absence of a pathognomonic test. The objective was to find the best manifestations that discriminate between lipedema and lymphedema and to build a diagnosis…

Forner-Cordero I, Muñoz-Langa J, Morilla-Bellido L · International angiology : a journal of the International Union of Angiology · 26 fev 2025

Nível de evidência 3 de 5

More than meets the eye: phenomenological insights into the functioning of people with lipoedema

The aim of this study was to explore the functioning of people with lipoedema from their perspective. This was a qualitative study following a phenomenological perspective using individual in-depth interviews with a convenience…

Kloosterman LM et al. · International journal of qualitative studies on health and well-being · 20 fev 2025

Nível de evidência 3 de 5

Lipedema awareness in fibromyalgia

ObjectivesTo evaluate the presence of lipedema and lipedema-related factors in fibromyalgia patients.MethodsThe study included 100 female patients over the age of 18 who met the fibromyalgia diagnostic criteria. The patients were…

Bolkan Günaydın E et al. · Phlebology · 14 fev 2025

Nível de evidência 3 de 5

Is lipedema a progressive disease?

It is not yet known whether lipedema is a progressive chronic disease or not. The aim of this paper is to describe the long-term changes in the volume of the lower limbs. The primary endpoint of this prospective cohort study of…

Forner-Cordero I, Muñoz-Langa J · Vascular medicine (London, England) · 20 jan 2025

Nível de evidência 3 de 5

Comparative Analysis of Liposuction and Conservative Treatment in Lipedema Patients: A Modified Body-Q Questionnaire Study

Background: Despite its estimated high prevalence among women and increasing awareness, lipedema remains under-investigated. Ignoring its debilitating nature, surgical treatment for this condition is frequently covered by health…

Aitzetmüller-Klietz M et al. · Journal of clinical medicine · 6 jan 2025

Nível de evidência 3 de 5

Characterization of Pain in Lipedema: Reliability and Validity of Pain Pressure Thresholds and Hand-Held Sphygmomanometer Assessments in People with Lipedema

Background: Lipedema is a chronic condition characterized by abnormal deposition of subcutaneous adipose tissue, leading to pain. The lack of internationally recognized diagnostic criteria complicates the characterization of…

Bettariga F et al. · Lymphatic research and biology · 24 dez 2024

Nível de evidência 3 de 5

Disability and emotional symptoms in women with lipedema: A comparison with overweight/obese women

Lipedema is characterized by the painful abnormal deposition of adipose tissue in the lower limbs and is often misdiagnosed as obesity. Considering the numerous bothersome physical symptoms of lipedema, women with lipedema may…

Chachaj A et al. · Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 1 dez 2024

Nível de evidência 3 de 5

Comparison of postoperative analgesia requirements between lipoedema and lymphoedema patients undergoing lower limb liposuction

Lymphoedema and lipoedema can present similarly however have different aetiologies and should be considered as distinct clinical entities. Pain is a distinguishing feature of lipoedema. Liposuction can be used in both conditions…

Hilder KR, Munnoch DA · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 28 nov 2024

Nível de evidência 3 de 5

Transcriptomics of Subcutaneous Tissue of Lipedema Identified Differentially Expressed Genes Involved in Adipogenesis, Inflammation, and Pain

Lipedema is a disease typically affecting women with a symmetrical, painful fat distribution disorder, which is hypothesized to be caused by impaired adipogenesis, inflammation, and extracellular matrix remodeling, leading to…

Streubel MK et al. · Plastic and reconstructive surgery. Global open · 8 nov 2024

Nível de evidência 3 de 5

Evaluation of the Effectiveness of Compression Therapy Combined with Exercises Versus Exercises Only Among Lipedema Patients Using Various Outcome Measures

The treatment of lipedema remains challenging, largely due to widespread misconceptions. Selecting the appropriate treatment method necessitates the use of accurate outcome measures. This study aims to evaluate the effectiveness…

Czerwińska M et al. · Life (Basel, Switzerland) · 22 out 2024

Nível de evidência 3 de 5

A retrospective cohort study: Waterjet-assisted liposuction reduces inflammation but increases the risk of hypokalemia in patients with lipoedema

Lipoedema is a congenital fat distribution disorder. It leads to a pathological increase in adipose tissue due to a hypertrophy and hyperplasia of the adipocytes. Currently, the disease affects approximately 10% of women. A…

Hoffmann J et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 13 out 2024

Nível de evidência 3 de 5

[Commentary on the Article of Philipp Moog, Edith Gawlik, Stefan Eisenreich et al. The Cost of Lipedema Treatment Exceeds the DRG Revenues - Evaluation of the Surgical Treatment Costs Of Lipedema (Stage III) at a German University Clinic]

Sem abstract disponível no PubMed.

Allert S · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 1 out 2024

Nível de evidência 3 de 5

Characteristics and Clinical Features of Patients with Lipedema in Saudi Arabia: A Cross-sectional Comprehensive Assessment

Lower limb swelling presents a diagnostic challenge with diverse causes, including well-known issues like venous insufficiency and lymphedema, and less-understood conditions like lipedema. Lipedema, involving abnormal fat…

Alosaimi K, Mortada H, Alshomer F · Plastic and reconstructive surgery. Global open · 18 set 2024

Nível de evidência 3 de 5

[The Cost of Lipoedema Treatment Exceeds the DRG Revenues - Evaluation of the Surgical Treatment Costs of Lipoedema (Stage III) at a German University Clinic]

Liposuction for stage III lipoedema is a guideline-based but also time-consuming treatment, which can be carried out under specific conditions at the expense of the German statutory health insurance companies (SHI) based on a…

Moog P et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 16 set 2024

Nível de evidência 3 de 5

Micromassage Compression Leggings Associated with Physical Exercise: Pilot Study and Example of Evaluation of the Clinical and Instrumental Effectiveness of Conservative Treatment in Lipedema

We evaluated the effect of compression leggings with micromassage in association with physical activity on women with lipedema, not previously treated and without recent changes in body weight. The treatment resulted in an…

Ricolfi L et al. · Life (Basel, Switzerland) · 8 jul 2024

Nível de evidência 3 de 5

Liposuction as a Treatment for Lipedema: A Scoping Review

Lipedema is the progressive symmetrical deposition of subcutaneous fat and fluid in the lower body, ordinarily sparing the trunk, upper limbs, face, and neck. It may follow an autosomal dominant inheritance pattern. The gold…

Bejar-Chapa M et al. · Plastic and reconstructive surgery. Global open · 2 jul 2024

Nível de evidência 3 de 5

A retrospective comparative study of patient-reported outcome measures, pre-treatment and twelve months post-treatment using tumescent liposuction for the management of lower limb lipoedema

Lipoedema is a painful adipose tissue disorder, affecting the limbs of women, that is resistant to diet and exercise. The purpose of the study was to evaluate the retrospective health-related quality-of-life (HRQoL) outcomes for…

Malcolm L · JPRAS open · 4 jun 2024

Nível de evidência 3 de 5

TRPV4-Expressing Tissue-Resident Macrophages Regulate the Function of Collecting Lymphatic Vessels via Thromboxane A2 Receptors in Lymphatic Muscle Cells

TRPV4 channels are critical regulators of blood vascular function and have been shown to be dysregulated in many disease conditions in association with inflammation and tissue fibrosis. These are key features in the…

Schulz ME et al. · bioRxiv : the preprint server for biology · 23 mai 2024

Nível de evidência 3 de 5

The Expression of Adipogenic Marker Is Significantly Increased in Estrogen-Treated Lipedema Adipocytes Differentiated from Adipose Stem Cells In Vitro

Lipedema is a chronic, idiopathic, and painful disease characterized by an excess of adipose tissue in the extremities. The goal of this study is to characterize the gene expression of estrogen receptors (ERα and ERβ), G…

Al-Ghadban S et al. · Biomedicines · 9 mai 2024

Nível de evidência 3 de 5

National Lymphoedema Conference 2024: session summaries

The 11th annual National Lymphoedema Conference, organised by the British Journal of Community Nursing in association with the British Lymphology Society and Lipoedema UK, was hosted at the America Square Conference Centre,…

Hashimi S, Rajagopalan U · British journal of community nursing · 1 abr 2024

Nível de evidência 3 de 5

Author Correction: Aldo-keto reductase 1C2 (AKR1C2) as the second gene associated to non-syndromic primary lipedema: investigating activating mutation or overexpression as causative factors

Correction to: Eur Rev Med Pharmacol Sci 2023; 27 (6 Suppl): 127-136-DOI: 10.26355/eurrev_202312_34697 After publication and following some post-publication concerns, the authors have applied the following corrections to the…

Kaftalli J et al. · European review for medical and pharmacological sciences · 1 mar 2024

Nível de evidência 3 de 5

Observational Study on a Large Italian Population with Lipedema: Biochemical and Hormonal Profile, Anatomical and Clinical Evaluation, Self-Reported History

We analyzed the medical condition of 360 women affected by lipedema of the lower limbs in stages 1, 2, and 3. The data were assessed for the whole population and compared between different clinical stages, distinguishing between…

Patton L et al. · International journal of molecular sciences · 27 jan 2024

Nível de evidência 3 de 5

Expression of Concern

The Editor in Chief and the Publisher are issuing an expression of concern to alert readers to the fact that the Special Issue titled "Omics sciences in the personalization of diagnosis and therapy" and, in particular, the…

Listed NA · European review for medical and pharmacological sciences · 1 jan 2024

Nível de evidência 3 de 5

Serum Metabolomic Profiling of Patients with Lipedema

Lipedema is a chronic condition characterized by disproportionate and symmetrical enlargement of adipose tissue, predominantly affecting the lower limbs of women. This study investigated the use of metabolomics in lipedema…

Kempa S et al. · International journal of molecular sciences · 13 dez 2023

Nível de evidência 3 de 5

Assessment of lower extremity venous insufficiency and lipedema and their association with knee symptoms, functions, and quality of life in patients with knee osteoarthritis

To evaluate the effects of the venous insufficiency (VI) or lipedema on the symptoms, functions, and quality of life (QoL) of patients with knee osteoarthritis (OA). 96 patients with stage 3/4 knee OA were included in the study.…

Ekti H et al. · Phlebology · 13 dez 2023

Nível de evidência 3 de 5

Obesity, thrombosis, venous disease, lymphatic disease, and lipedema: An obesity medicine association (OMA) clinical practice statement (CPS) 2023

This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) is intended to provide clinicians with an overview on obesity, thrombosis, venous disease, lymphatic disease, and lipedema. The scientific support for this…

Bindlish S et al. · Obesity pillars · 19 out 2023

Nível de evidência 3 de 5

Effect of Physical Therapy on Circumference Measurement and Extremity Volume in Patients Suffering from Lipedema with Secondary Lymphedema

Background: Lipedema is a chronic and progressive disease. Many complications can occur if the disease is not treated. The most important of these complications is lipedema with secondary lymphedema. There are very few…

Esmer M, Schingale FJ · Lymphatic research and biology · 3 out 2023

Nível de evidência 3 de 5

Enhanced Angiogenesis in HUVECs Preconditioned with Media from Adipocytes Differentiated from Lipedema Adipose Stem Cells In Vitro

Lipedema is a connective tissue disorder characterized by increased dilated blood vessels (angiogenesis), inflammation, and fibrosis of the subcutaneous adipose tissue. This project aims to gain insights into the angiogenic…

Al-Ghadban S et al. · International journal of molecular sciences · 1 set 2023

Nível de evidência 3 de 5

Body mass index vs. waist-to-height-ratio in patients with lipohyperplasia dolorosa (vulgo lipedema)

Lipedema, also known as lipohyperplasia dolorosa (LiDo), is a painful condition affecting women, causing a disproportionate accumulation of subcutaneous adipose tissue in the extremities. It carries a lower risk of diabetes and…

Brenner E et al. · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 30 ago 2023

Nível de evidência 3 de 5

The Advanced Care Study: Current Status of Lipedema in Spain, A Descriptive Cross-Sectional Study

The pathologic features of fatty tissue in lipedema are often challenging to diagnose, thus allowing for variable bias and leading to underdiagnosis. Lipedema is a disease that is currently little known worldwide, but it…

Carballeira Braña A, Poveda Castillo J · International journal of environmental research and public health · 25 ago 2023

Nível de evidência 3 de 5

Understanding the Vicious Circle of Pain, Physical Activity, and Mental Health in Lipedema Patients-A Response Surface Analysis

Lipedema is a widespread disease with painful accumulations of subcutaneous fat in the legs and arms. Often, obesity co-occurs. Many patients suffer from impairment in mobility and mental health. Obesity and mental health in turn…

Aitzetmüller-Klietz M et al. · Journal of clinical medicine · 16 ago 2023

Nível de evidência 3 de 5

[Settlement of the surgical treatment of lipoedema]

The billing of lipoedema treatment in Germany has come to be heterogeneous. This is due to the decision of the Federal Joint Committee ("Gemeinsamer Bundesausschuss", G-BA) to acknowledge lipoedema stage III as a treatment to be…

Motamedi M et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 20 jul 2023

Nível de evidência 3 de 5

Patient-Reported Outcomes of Liposuction for Lipedema Treatment

Lipedema, as a disabling and consequential disease, is gaining more awareness due to its potential omnipresence. Patients suffering from lipedema show a characteristic painful display of symmetric accumulations of adipose tissue.…

Kirstein F et al. · Healthcare (Basel, Switzerland) · 13 jul 2023

Nível de evidência 3 de 5

Frequency of lipoedema in patients consulting a vein clinic for mild to moderate superficial venous disorder with symptoms: A retrospective analysis

Lower limb lipoedema is a chronic condition of the adipose connective tissue of the skin that affects women. Its frequency is not well known, hence the main objective of this study. Retrospective analysis of the records of…

Rastel D, Urbinelli R · Journal de medecine vasculaire · 24 jun 2023

Nível de evidência 3 de 5

Semiautomated segmentation of lower extremity MRI reveals distinctive subcutaneous adipose tissue in lipedema: a pilot study

Lipedema is a painful subcutaneous adipose tissue (SAT) disease involving disproportionate SAT accumulation in the lower extremities that is frequently misdiagnosed as obesity. We developed a semiautomatic segmentation pipeline…

Taylor SL et al. · Journal of medical imaging (Bellingham, Wash.) · 15 mai 2023

Nível de evidência 3 de 5

Breaking the circle-effectiveness of liposuction in lipedema

Lipedema is a common chronic fat distribution disorder often aligned with pain and reduced quality of life affecting 6-10% of the female population. Although lipedema has acquired more scientific attention in the last decade,…

Seefeldt T et al. · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 15 mai 2023

Nível de evidência 3 de 5

A Comparative Analysis to Dissect the Histological and Molecular Differences among Lipedema, Lipohypertrophy and Secondary Lymphedema

Lipedema, lipohypertrophy and secondary lymphedema are three conditions characterized by disproportionate subcutaneous fat accumulation affecting the extremities. Despite the apparent similarities and differences among their…

von Atzigen J et al. · International journal of molecular sciences · 20 abr 2023

Nível de evidência 3 de 5

Lipoedema: a neglected area of women's health

Lipoedema is an adipose tissue disorder almost exclusively affecting women. Evidence shows lipoedema is both poorly recognised and misdiagnosed which results in many women struggling to get a diagnosis and to gain access to…

Warrilow M · British journal of community nursing · 1 abr 2023

Nível de evidência 3 de 5

Lipedema: Usefulness of 3D Ultrasound Diagnostics

Background: To define the usefulness of three-dimensional (3D) ultrasound diagnostics for lipedema. Methods and Results: In this study, starting in May 2021, it was decided to apply 3D ultrasound diagnostics in the evaluation of…

Cestari M · Lymphatic research and biology · 28 mar 2023

Nível de evidência 3 de 5

Summary: Appropriate Use Criteria for Lymphoscintigraphy in Sentinel Node Mapping and Lymphedema/Lipedema

Expert representatives from 11 professional societies, as part of an autonomous work group, researched and developed appropriate use criteria (AUC) for lymphoscintigraphy in sentinel lymph node mapping and lymphedema. The…

Donohoe KJ et al. · Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 23 mar 2023

Nível de evidência 3 de 5

Surgical lymphology. Therapy option for lymphoedema and lipohyperplasia dolorosa

The typical therapy in lymphology is conservative. However, reconstructive and resective treatments for primary and secondary lymphoedema as well as resective procedures for lipohyperplasia dolorosa (LiDo) "lipedema" have been…

Cornely ME · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 1 fev 2023

Nível de evidência 3 de 5

Functioning of People with Lipoedema According to All Domains of the International Classification of Functioning, Disability and Health: A Scoping Review

Lipoedema is a painful non-pitting diffuse "fatty" swelling, usually confined to the legs, that occurs mainly in women. This scoping review aimed to provide an overview of the available research on the functioning of people with…

Kloosterman LM et al. · International journal of environmental research and public health · 21 jan 2023

Nível de evidência 3 de 5

Younger Women with Lipedema, Their Experiences with Healthcare Providers, and the Importance of Social Support and Belonging: A Qualitative Study

Lipedema is a chronic adipose tissue disorder affecting approximately 11% of women worldwide. The illness is often misdiagnosed as obesity, and because of this, women often struggle in meetings with healthcare providers. Few…

Christoffersen V, Tennfjord MK · International journal of environmental research and public health · 20 jan 2023

Nível de evidência 3 de 5

Diagnostic Comparability of Ratio of Tissue Dielectric Constant (TDC) Between Patients with Lipedema and Those with Lower Limb Lymphedema (LLL): A Prospective Observational Study

Lipedema is usually thought of as a dis-ease of women. Potentially diagnostic comparative data is needed between patients with lip-edema and those with lower limb lymphedema (LLL). Since there is no gold standard to diagnose…

Tugral A, Bakar Y · Lymphology · 1 jan 2023

Nível de evidência 3 de 5

Summary document on safety and recommendations on liposuction for lipoedema: Joint British association of aesthetic plastic surgeons (BAAPS)/British association of plastic reconstructive and aesthetic surgeons (BAPRAS) expert liposuction group

Liposuction plays an important role as a surgical treatment option for lipoedema. This article serves to critically review the evidence in the literature, as well as explain the differences between the lipoedema population…

Dancey A et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 21 dez 2022

Nível de evidência 3 de 5

Genome-wide association study of a lipedema phenotype among women in the UK Biobank identifies multiple genetic risk factors

Lipedema is a common disorder characterized by excessive deposition of subcutaneous adipose tissue (SAT) in the legs, hips, and buttocks, mainly occurring in adult women. Although it appears to be heritable, no specific genes…

Klimentidis YC et al. · European journal of human genetics : EJHG · 16 nov 2022

Nível de evidência 3 de 5

Five-year results after total knee arthroplasty in lymphoedema and lipoedema: encouraging functional and clinical outcomes and low rates of infection

The aim of this study was to define outcomes after total knee arthroplasty (TKA) in lymphoedema and lipoedema patients managed by a multidisciplinary team and daily compression bandaging. A retrospective study was performed in a…

Granger L et al. · International orthopaedics · 8 set 2022

Nível de evidência 3 de 5

The Effect of a Low-Carbohydrate, High-Fat Diet versus Moderate-Carbohydrate and Fat Diet on Body Composition in Patients with Lipedema

Lipedema is a disorder characterized by an excessive accumulation of subcutaneous body fat, mainly bilateral and symmetrical accumulation of fat deposits, particularly in the lower extremities excluding feet. Pain (spontaneous or…

Jeziorek M et al. · Diabetes, metabolic syndrome and obesity : targets and therapy · 22 ago 2022

Nível de evidência 3 de 5

Stages of lipoedema: experiences of physical and mental health and health care

Lipoedema is a progressive adipose (fat) disorder, and little is known about its psychological effect. This study aimed to determine the experiences of physical and mental health and health care across stages of lipoedema.…

Clarke C et al. · Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 16 ago 2022

Nível de evidência 3 de 5

Lipoedema: detailed left atrial volumetric and strain analysis by three-dimensional speckle-tracking echocardiography from the MAGYAR-Path Study

Lipoedema is a chronic feminine disease with disproportional painful fat deposition of the lower body half and occassional arm affection. The objective of the present study was to assess LA volumetric and functional properties by…

Nemes A et al. · Postepy dermatologii i alergologii · 14 jul 2022

Nível de evidência 3 de 5

Lymphatic function and anatomy in early stages of lipedema

Lipedema is an inflammatory subcutaneous adipose tissue disease that develops in women and may progress to lipolymphedema, a condition similar to lymphedema, in which lymphatic dysfunction results in irresolvable edema. Because…

Rasmussen JC et al. · Obesity (Silver Spring, Md.) · 15 jun 2022

Nível de evidência 3 de 5

A Scoping Review of Available Tools in Measurement of the Effectiveness of Conservative Treatment in Lipoedema

(1) Background: Due to insufficient knowledge of lipoedema, the treatment of this disease is undoubtedly challenging. However, more and more researchers attempt to incorporate the most effective lipoedema treatment methods. When…

Czerwińska M, Teodorczyk J, Hansdorfer-Korzon R · International journal of environmental research and public health · 10 jun 2022

Nível de evidência 3 de 5

Lipedema prevalence and risk factors in Brazil

Lipedema is characterized as an abnormal deposition of fat in the buttocks and legs bilaterally that may be accompanied by swelling, pain, and tenderness. It is still often confused with more frequent conditions such as obesity…

Amato ACM et al. · Jornal vascular brasileiro · 23 mai 2022

Nível de evidência 3 de 5

Multi-Level Analysis of Adipose Tissue Reveals the Relevance of Perivascular Subpopulations and an Increased Endothelial Permeability in Early-Stage Lipedema

Lipedema is a chronic, progressive disease of adipose tissue with unknown etiology. Based on the relevance of the stromal vascular fraction (SVF) cell population in lipedema, we performed a thorough characterization of…

Strohmeier K et al. · Biomedicines · 18 mai 2022

Nível de evidência 3 de 5

Characteristics and Patient Reported Outcome Measures in Lipedema Patients-Establishing a Baseline for Treatment Evaluation in a High-Volume Center

Lipedema patients suffer not only from visual stigma but also reduction in their quality of life through pain and performance loss in daily life. In clinical practice, it is still difficult to reliably diagnose the disease. This…

Hamatschek M et al. · Journal of clinical medicine · 17 mai 2022

Nível de evidência 3 de 5

A 10-Year Retrospective before-and-after Study of Lipedema Surgery: Patient-Reported Lipedema-Associated Symptom Improvement after Multistage Liposuction

Despite an increasing demand for surgical treatment of lipedema, the evidence for liposuction is still limited. Little is known about the influence of disease stage, patient age, body mass index, or existing comorbidities on…

Kruppa P et al. · Plastic and reconstructive surgery · 1 mar 2022

Nível de evidência 3 de 5

What do lymphedema patients expect from a treatment and what do they achieve? A descriptive study

Lymphedema is characterized by swelling and fibroadipose tissue deposition that is a physically, psychologically, and socially debilitating condition due to chronic and progressive nature of the disease. Treatment benefit…

Duygu Yildiz E, Bakar Y, Keser I · Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing · 26 jan 2022

Nível de evidência 3 de 5

Persistent lipedema pain in patients after bariatric surgery: a case series of 13 patients

Lipedema often remains undiagnosed in patients with obesity, leading to mismanagement of treatment. Because of this, despite remarkable weight loss after bariatric surgery and decreases in hip and abdomen circumference, some…

Cornely ME et al. · Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 7 jan 2022

Nível de evidência 3 de 5

[Differential diagnosis of chronic lower limb edema]

Lower extremity edema is a common complaint of patients across all medical specialties. This is a wide group of conditions, ranging from relatively minor conditions such as false swelling in lipedema to life-threatening…

Ambrož D · Vnitrni lekarstvi · 1 jan 2022

Nível de evidência 3 de 5

Physical Therapy in Women with Early Stage Lipedema: Potential Impact of Multimodal Manual Therapy, Compression, Exercise, and Education Interventions

Background: Lipedema is a distinct adipose disorder from obesity necessitating awareness as well as different management approaches to address pain and optimize quality of life (QoL). The purpose of this proof-of-principle study…

Donahue PMC et al. · Lymphatic research and biology · 8 nov 2021

Nível de evidência 3 de 5

Lipoedema as a Social Problem. A Scoping Review

(1) Background: Lipoedema is a disease characterized by excessive bilateral and symmetrical accumulation of subcutaneous tissue in the lower extremities. It is a poorly understood condition, and low awareness of its existence…

Czerwińska M, Ostrowska P, Hansdorfer-Korzon R · International journal of environmental research and public health · 28 set 2021

Nível de evidência 3 de 5

Women's experiences of living with lipedema

Lipedema is a chronic, progressive disease that almost exclusively affects women and often misdiagnosed as obesity or primary lymphedema. Research concerning lipedema is sparse, and there is a lack of studies focusing on women's…

Melander C, Juuso P, Olsson M · Health care for women international · 12 jul 2021

Nível de evidência 3 de 5

Standard of care for lipedema in the United States

Lipedema is a loose connective tissue disease predominantly in women identified by increased nodular and fibrotic adipose tissue on the buttocks, hips and limbs that develops at times of hormone, weight and shape change including…

Herbst KL et al. · Phlebology · 28 mai 2021

Nível de evidência 3 de 5

Survey Outcomes of Lipedema Reduction Surgery in the United States

Lipedema is a loose connective tissue disease affecting the limbs of women, that is difficult to lose by diet, exercise, or bariatric surgery. Publications from Europe demonstrate that lipedema reduction surgery improves quality…

Herbst KL et al. · Plastic and reconstructive surgery. Global open · 23 abr 2021

Nível de evidência 3 de 5

Ultrasound criteria for lipedema diagnosis

Lipedema is characterized by the deposition of abnormal fat in the lower and upper limbs bilaterally. It is a disease with high prevalence and genetic characteristics. Non-specific and non-quantified increases in the thickness of…

Amato ACM et al. · Phlebology · 15 abr 2021

Nível de evidência 3 de 5

[Lipedema : an unknown entity]

Lipedema is an infrequently recognized disorder. It is characterized by bilateral painful enlargement of the legs due to abnormal depositions of subcutaneous fat, that can result in considerable disability. The diagnosis is…

Naef V, Alvarez Martinez D, Cortes B · Revue medicale suisse · 31 mar 2021

Nível de evidência 3 de 5

A Distinct Cytokine Profile and Stromal Vascular Fraction Metabolic Status without Significant Changes in the Lipid Composition Characterizes Lipedema

Lipedema is an adipose tissue disorder characterized by the disproportionate increase of subcutaneous fat tissue in the lower and/or upper extremities. The underlying pathomechanism remains unclear and no molecular biomarkers to…

Wolf S et al. · International journal of molecular sciences · 24 mar 2021

Nível de evidência 3 de 5

JUXTA-ARTICULAR ADIPOSIS DOLOROSA IN LIPEDEMA PATIENTS

Both lipedema and juxta-articular adiposis dolorsa are painful disorders of subcutaneous adipose tissue. We investigated 297 female patients with lipedema treated at our department for the presence of juxta-articular adiposis…

Wollina U · Georgian medical news · 1 jan 2021

Nível de evidência 3 de 5

Ketogenic diet as a potential intervention for lipedema

Lipedema (LI) is a common yet misdiagnosed condition, often misconstrued with obesity. LI affects women almost exclusively, and its painful and life-changing symptoms have long been thought to be resistant to the lifestyle…

Keith L et al. · Medical hypotheses · 27 nov 2020

Nível de evidência 3 de 5

3D Spheroids Derived from Human Lipedema ASCs Demonstrated Similar Adipogenic Differentiation Potential and ECM Remodeling to Non-Lipedema ASCs In Vitro

The growth and differentiation of adipose tissue-derived stem cells (ASCs) is stimulated and regulated by the adipose tissue (AT) microenvironment. In lipedema, both inflammation and hypoxia influence the expansion and…

Al-Ghadban S et al. · International journal of molecular sciences · 7 nov 2020

Nível de evidência 3 de 5

The Effects of Complex Decongestive Physiotherapy Applications on Lower Extremity Circumference and Volume in Patients with Lipedema

Background: The aim of this study is to investigate the effect of complex decongestive physiotherapy (CDP) plus intermittent pneumatic compression (IPC) applications on lower extremity limb circumference and volume in patients…

Volkan-Yazıcı M, Yazici G, Esmer M · Lymphatic research and biology · 30 out 2020

Nível de evidência 3 de 5

Interstitial Fluid in Lipedema and Control Skin

Background: Fluid in lymphedema tissue appears histologically as spaces around vessels and between dermal skin fibers. Lipedema is a painful disease of excess loose connective tissue (fat) in limbs, almost exclusively of women,…

Allen M, Schwartz M, Herbst KL · Women's health reports (New Rochelle, N.Y.) · 14 out 2020

Nível de evidência 3 de 5

Cross-sectional validity and specificity of comprehensive measurement in lymphedema and lipedema of the lower extremity: a comparison of five outcome instruments

Literature on the validity of outcome measurement in lymphedema and lipedema is very sparse. This study aimed to examine the convergent, divergent and discriminant validity of a set of 5 instruments in both conditions.…

Angst F et al. · Health and quality of life outcomes · 22 jul 2020

Nível de evidência 3 de 5

The impact of lower body compression garment on left ventricular rotational mechanics in patients with lipedema-Insights from the three-dimensional speckle tracking echocardiographic MAGYAR-Path Study

Lipedema is a lymphedema-masquerading symmetrical, bilateral and disproportional obesity. Its conservative maintenance treatment comprises the use of flat-knitted compression pantyhoses. Lipedema is known to be associated with…

Nemes A et al. · Clinical obesity · 23 jun 2020

Nível de evidência 3 de 5

Extended overview of the longitudinal pain-depression association: A comparison of six cohorts treated for specific chronic pain conditions

The aim was to quantify and to compare the associations between longitudinal changes in pain and depression in different chronic pain conditions. Data were retrieved from 6 observational cohort studies. From baseline to the…

Angst F et al. · Journal of affective disorders · 19 mai 2020

Nível de evidência 3 de 5

Are increased left ventricular strains compensatory effects in lipedema? Detailed analysis from the three-dimensional speckle-tracking echocardiographic MAGYAR-Path Study

Lipedema is a chronic, common but underdiagnosed disease masquerading obesity, with female predominance, characterized by disproportional abnormal adipose tissue distribution of the lower and also upper extremities. The present…

Nemes A et al. · Journal of clinical ultrasound : JCU · 11 mai 2020

Nível de evidência 3 de 5

Chronic oedema and lymphoedema: what is the difference?

Chronic oedema is a term that encompasses several causes that lead to oedema formation in any part of the body. This includes lymphoedema and its subcategories. Despite the assumption that these are different, there are more…

Cooper-Stanton G · British journal of community nursing · 1 abr 2020

Nível de evidência 3 de 5

Water-jet-assisted liposuction for the treatment of lipedema: Standardized treatment protocol and results of 63 patients

Lipedema is a condition of painful increase in subcutaneous fat affecting almost exclusively women. Several studies have examined the effectiveness of liposuction in the treatment of lipedema, but none has focused on…

Witte T et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 14 mar 2020

Nível de evidência 3 de 5

The role of IL-6 gene polymorphisms in the risk of lipedema

Lipedema is a disorder of adipose tissue characterized by abnormal subcutaneous fat deposition, leading to swelling and enlargement of the lower limbs and trunk. The aim of this study was to evaluate the lipedema phenotype by…

Di Renzo L et al. · European review for medical and pharmacological sciences · 1 mar 2020

Nível de evidência 3 de 5

Prevention of Progression of Lipedema With Liposuction Using Tumescent Local Anesthesia: Results of an International Consensus Conference

Lipedema is a chronic, progressive disorder of subcutaneous adipose tissue that usually affects the lower extremities of women. Also known as "two-body syndrome," the fat accumulations in lipedema are unsightly and painful. The…

Sandhofer M et al. · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 1 fev 2020

Nível de evidência 3 de 5

Lipedema: A Commonly Misdiagnosed Fat Disorder

Lipedema is a fat disorder that is often misdiagnosed. It was first identified at the Mayo Clinic in 1940, but medical schools do not include it in their curriculum and is therefore poorly understood. It presents as…

Caruana M · Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses · 1 jan 2020

Nível de evidência 3 de 5

[Pain in lipoedema, fat in lipoedema and its consequences: results of a patient survey based on a pain questionnaire]

640 patients from a specialist clinic for operative lymphology were surveyed with the help by a questionnaire issued by the German Society of Pain Therapy (Deutsche Schmerzgesellschaft e. V.). This survey collected responses to…

Gensior MHL, Cornely M · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 14 ago 2019

Nível de evidência 3 de 5

[Whole-body surface assessment - implementation and experiences with 360° 3D whole-body scans: opportunities to objectively monitor the extremities and the body trunk]

Three-dimensional surface imaging (3DSI) has proven to be useful in providing objective aid to the planning process and documentation of various plastic-surgical procedures. Although this technology is routinely used in the…

Etzel L et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 14 ago 2019

Nível de evidência 3 de 5

Clinical Features of Nonobese, Apparently Healthy, Japanese Men With Reduced Adipose Tissue Insulin Sensitivity

Adipose tissue insulin resistance has been observed in obese subjects and is considered an early metabolic defect that precedes insulin resistance in muscle and liver. Although Asians can readily develop metabolic disease without…

Sugimoto D et al. · The Journal of clinical endocrinology and metabolism · 1 jun 2019

Nível de evidência 3 de 5

[Prior cost approval for treatment of lipoedema: things to consider]

Lipoedema used to be a rather unknown disease. In the past five years, it has gained increasing awareness, especially through media attention. Besides non-surgical treatment by complex conservative decongestion, there are an…

Motamedi M, Herold C, Allert S · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 16 abr 2019

Nível de evidência 3 de 5

[The Swollen Leg in Vascular Medical Practice]

In case of an acute leg swelling a deep leg vein thrombosis needs to be excluded. In order to do this, compression sonography and the D-dimer-test are applied in the framework of an established diagnostic algorithm. The ensuing…

Präve F, Hoffmann K · Deutsche medizinische Wochenschrift (1946) · 14 mar 2019

Nível de evidência 3 de 5

[Quantitative volumetric analysis of the lower extremity: validation against established tape measurement and water displacement]

Tape measures continue to be used for the diagnosis and evaluation of lipoedema and lymphoedema in the clinical routine. Extremity volumes are calculated based on standardised circumferential measurements. Other volume…

Koban KC et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 8 jan 2019

Nível de evidência 3 de 5

[Imaging for treatment planning in lipo-and lymphedema]

Lipoedema is a progressive disease, which predominantly affects women. It is characterised by circumferential growth, with increase in fat tissue of the extremities, and can lead to oedema. In contrast, the lymphoedema is defined…

Zetzmann K et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 8 jan 2019

Nível de evidência 3 de 5

[Lipedema - basics and current hypothesis of pathomechanism]

Lipoedema is a painful, chronic progressive disorder of adipose tissue, characterised by symmetrical swelling of the lower and/or upper limbs. Due to a lack of awareness, lipoedema is frequently misdiagnosed. However, accurate…

Wiedner M, Aghajanzadeh D, Richter DF · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 8 jan 2019

Nível de evidência 3 de 5

Characterizing Lower Extremity Lymphedema and Lipedema with Cutaneous Ultrasonography and an Objective Computer-Assisted Measurement of Dermal Echogenicity

Background: Sonographic findings differ in patients with primary lipedema from those with lymphedema. This project was designed to quantify those differences and objectively characterize findings of lipedema and lymphedema in the…

Iker E et al. · Lymphatic research and biology · 7 jan 2019

Nível de evidência 3 de 5

Subcutaneous adipose tissue therapy reduces fat by dual X-ray absorptiometry scan and improves tissue structure by ultrasound in women with lipoedema and Dercum disease

Lipoedema is painful nodular subcutaneous adipose tissue (SAT) on legs and arms of women sparing the trunk. People with Dercum disease (DD) have painful SAT masses. Lipoedema and DD fat resists loss by diet and exercise.…

Ibarra M et al. · Clinical obesity · 24 set 2018

Nível de evidência 3 de 5

Lymphoscintigraphic findings in patients with lipedema

Lipedema is a syndrome that is characterised by edema, an accumulation of fat, pain and haematomas in the lower limbs that principally affects women. Diagnosis is currently based on clinical criteria, since there is no accurate…

Forner-Cordero I et al. · Revista espanola de medicina nuclear e imagen molecular · 28 ago 2018

Nível de evidência 3 de 5

[Survey on the diagnostics and therapy of patients with lymphedema and lipedema]

Implementation of guideline recommendations for the diagnosis and therapy of lipedema and lymphedema seems to be problematic in daily routine. Systematic data for Germany are missing. The aim of the study was data collection…

Reich-Schupke S, Mohren E, Stücker M · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 jun 2018

Nível de evidência 3 de 5

Lipedema: A Commonly Misdiagnosed Fat Disorder

Lipedema is a fat disorder that is often misdiagnosed. It was first identified at the Mayo Clinic in 1940, but medical schools do not include it in their curriculum and is therefore poorly understood. It presents as…

Caruana M · Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses · 1 jan 2018

Nível de evidência 3 de 5

Left ventricular rotational mechanics differ between lipedema and lymphedema: Insights from the three-dimensional speckle tracking echocardiographic MAGYAR-path study

The present study aimed to assess LV rotational mechanics by three-dimensional speckle-tracking echocardiography (3DSTE) in lipedema (n=25), lymphedema (n=26) patient groups with age- and gender-matched healthy controls (n=54). 3…

Nemes A et al. · Lymphology · 1 jan 2018

Nível de evidência 3 de 5

Quality of life in patients with primary and secondary lymphedema in the community

Lymphedema is a complex and burdensome medical problem and requires continuous specific therapy. The aim of this cross-sectional study of community lymphedema care in the metropolitan area of Hamburg, Germany, was to evaluate…

Herberger K et al. · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 27 abr 2017

Nível de evidência 3 de 5

Differentiating lipedema and Dercum's disease

People with lipedema or Dercum's disease (DD) can have a similar distribution of excess painful nodular subcutaneous adipose tissue (SAT), making them difficult to differentiate. Case series of 94 patients with DD, 160 with…

Beltran K, Herbst KL · International journal of obesity (2005) · 18 nov 2016

Nível de evidência 3 de 5

Diagnosis and management of lipoedema in the community

Lipoedema is a chronic progressive adipose disorder that affects mainly women and presents as symmetrical enlargement of the buttocks and legs. It is commonly misdiagnosed as obesity or lymphoedema, but careful assessment will…

Todd M · British journal of community nursing · 1 out 2016

Nível de evidência 3 de 5

Specialist approaches to managing lipoedema

While there is no proven cure for lipoedema, early detection is key as specialist treatments, complemented by self-management techniques, can improve symptoms and prevent progression. There is no universal approach as the correct…

Fetzer A · British journal of community nursing · 1 abr 2016

Nível de evidência 3 de 5

Long-term benefit of liposuction in patients with lipoedema: a follow-up study after an average of 4 and 8 years

Long-term results following liposuction in patients with lipoedema are available only for an average period of 4 years. To find out whether the improvement of complaints persists for a further 4 years. In a single-centre study,…

Baumgartner A, Hueppe M, Schmeller W · The British journal of dermatology · 26 dez 2015

Nível de evidência 3 de 5

[Recognising and treating lipidema OMIM 614103]

Lipedema is a poorly understood clinical entity that is frequently under-diagnosed and neglected or else confused with lymphoedema. However, in most cases, diagnosis is simple and does not usually necessitate laboratory…

Truchetet F, Bonhomme A · Annales de dermatologie et de venereologie · 6 ago 2015

Nível de evidência 3 de 5

Quality of life in women with lipoedema: a contextual behavioral approach

Lipoedema is a chronic, progressive adipose disorder of unknown etiology, often underdiagnosed or misdiagnosed as obesity. It manifests itself with accumulation of the fat in lower parts of the body and associated edema and, due…

Dudek JE, Białaszek W, Ostaszewski P · Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 28 jul 2015

Nível de evidência 3 de 5

Taking the plunge with lipoedema

Women wait decades for an accurate diagnosis of lipoedema. Earlier diagnosis is essential to prevent the condition progressing to lymphoedema, with its risk of life-threatening cellulitis.

Mason M · Nursing standard (Royal College of Nursing (Great Britain) : 1987) · 8 jul 2015

Nível de evidência 3 de 5

Early lipoedema diagnosis and the RCGP e-learning course

Frequently misdiagnosed as obesity, lipoedema is chronic condition involving an abnormal build-up of fat cells in the legs, thighs and buttocks that cannot be shifted by exercise or dieting. Estimated to affect up to 11% of the…

Fetzer A, Fetzer S · British journal of community nursing · 1 abr 2015

Nível de evidência 3 de 5

Application of microcurrents of bioresonance and transdermal delivery of active principles in lymphedema and lipedema of the lower limbs: a pilot study

Application of microcurrents of bioresonance may allow protein aggregates lysis and a related enhancement of lymphatic drainage. Combining bioresonance with transcutaneous passage of active principles, by means of skin…

Elio C et al. · Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia · 1 dez 2014

Nível de evidência 3 de 5

Treatment of elderly patients with advanced lipedema: a combination of laser-assisted liposuction, medial thigh lift, and lower partial abdominoplasty

Lipedema is a rare female disorder with a characteristic distribution of adipose tissue hypertrophy on the extremities, with pain and bruising. In advanced stages, reduction of adipose tissue is the only available effective…

Wollina U, Heinig B, Nowak A · Clinical, cosmetic and investigational dermatology · 23 jan 2014

Nível de evidência 3 de 5

Lipoedema: the first UK patient survey

Lipoedema UK was founded in 2012 by women with lipoedema and clinicians working in the Lymphoedema Service at St George's Hospital in London. Its patron is Professor Peter Mortimer, the UK's leading Lipoedema expert, and its…

Evans S · British journal of community nursing · 1 abr 2013

Nível de evidência 3 de 5

[Complications of liposuction]

Liposuction is the most frequent aesthetic procedure worldwide for adipose tissue reduction and treatment of lipedema. It is being employed with increasing frequency. In 2010, in the USA more than 200.000 liposuctions were…

Sattler G, Eichner S · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 mar 2013

Nível de evidência 3 de 5

Lipedema: an overview of its clinical manifestations, diagnosis and treatment of the disproportional fatty deposition syndrome - systematic review

Lipedema is a disproportionate, symmetrical fatty swelling characterized by pain and bruising existing almost exclusively among women. We undertook a systematic review of the available literature about lipedema, given the lack of…

Forner-Cordero I et al. · Clinical obesity · 3 ago 2012

Nível de evidência 3 de 5

Lipedema, a rare disease

Lipedema is a chronic disease of lipid metabolism that results in the symmetrical impairment of fatty tissue distribution and storage combined with the hyperplasia of individual fat cells. Lipedema occurs almost exclusively in…

Shin BW et al. · Annals of rehabilitation medicine · 30 dez 2011

Nível de evidência 3 de 5

Tumescent liposuction in lipoedema yields good long-term results

Lipoedema is a painful disease in women with circumscribed increased subcutaneous fatty tissue, oedema, pain and bruising. Whereas conservative methods with combined decongestive therapy (manual lymphatic drainage, compression…

Schmeller W, Hueppe M, Meier-Vollrath I · The British journal of dermatology · 17 nov 2011

Nível de evidência 3 de 5

Liposuction is an effective treatment for lipedema-results of a study with 25 patients

Lipedema is a painful, genetically induced abnormal deposition of subcutaneous fat in the extremities of almost exclusively women. The pathogenesis is unknown and no curative treatment is available. Conservative therapy…

Rapprich S, Dingler A, Podda M · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 7 set 2010

Nível de evidência 3 de 5

Lipoedema: presentation and management

Lipoedema is a distinct clinical condition characterized by bilateral, symmetrical enlargement of the buttocks and lower limbs owing to excess deposition of subcutaneous fat. It is found almost exclusively in women. The common…

Todd M · British journal of community nursing · 1 abr 2010

Nível de evidência 3 de 5

Microcannular tumescent liposuction in advanced lipedema and Dercum's disease

We evaluated the outcome and risks of tumescence liposuction in patients with advanced lipedema or Dercum's disease. Six patients treated at a single center during the years 2004 to 2008 have been included. All patients were…

Wollina U, Goldman A, Heinig B · Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia · 1 abr 2010

Nível de evidência 3 de 5

Lipedema: an inherited condition

Lipedema is a condition characterized by swelling and enlargement of the lower limbs due to abnormal deposition of subcutaneous fat. Lipedema is an under-recognized condition, often misdiagnosed as lymphedema or dismissed as…

Child AH et al. · American journal of medical genetics. Part A · 1 abr 2010

Nível de evidência 3 de 5

Pit-1 mutation and lipoedema in a family

A 23-year-old male was referred to our clinic with diagnosis of idiopathic isolated growth hormone deficiency. A detailed family history revealed short stature and swelling of legs which only affected females in four generations…

Bano G et al. · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 16 jul 2009

Nível de evidência 3 de 5

Water jet-assisted liposuction for patients with lipoedema: histologic and immunohistologic analysis of the aspirates of 30 lipoedema patients

Lipoedema is a fat distribution disorder causing massive, bilaterally symmetrical enlargement of the lower and in some cases the upper extremities in women. The atraumatic, anatomically appropriate procedure of water jet-assisted…

Stutz JJ, Krahl D · Aesthetic plastic surgery · 29 jul 2008

Nível de evidência 3 de 5

Cellulite: nature and aetiopathogenesis

Only a limited number of studies on cellulite have been published in the international literature and many of them reach somewhat antithetical conclusions. Consequently, it is not yet possible to reconcile the extreme differences…

Terranova F, Berardesca E, Maibach H · International journal of cosmetic science · 1 jun 2006

Nível de evidência 3 de 5

Tumescent liposuction: a new and successful therapy for lipedema

Lipedema is a rare and painful disease in women. Until recently, it could be treated only by conservative methods (combined physical therapy). To determine the efficacy and safety of surgery (liposuction) concerning appearance…

Schmeller W, Meier-Vollrath I · Journal of cutaneous medicine and surgery · 1 jan 2006

Nível de evidência 3 de 5

Management of lower limb lymphoedema in the United Kingdom

Many investigations and treatments exist for lower limb lymphoedema. We undertook a survey on the management of this condition by vascular surgeons and the resources available for its treatment in the UK. A questionnaire was…

Tiwari A, Myint F, Hamilton G · European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 1 dez 2005

Nível de evidência 3 de 5

[Differential diagnosis of leg edema]

Both generalized and localized edema needs to be submitted to a differential diagnostic investigation. In the case of edema affecting the lower extremities, in particular the Stemmer sign which is the inability to tent the skin…

Fries R · MMW Fortschritte der Medizin · 15 abr 2004

Nível de evidência 3 de 5

Microlymphatic aneurysms in patients with lipedema

"Lipedema," a special form of obesity syndrome, represents swelling of the legs due to an increase of subcutaneous adipose tissue. In 12 patients with lipedema of the legs and in 12 healthy subjects (controls), fluorescence…

Amann-Vesti BR, Franzeck UK, Bollinger A · Lymphology · 1 dez 2001

Nível de evidência 3 de 5

[Involvement of the lymphatic system in primary non-lymphogenic edema of the leg. Studies with 2-compartment lymphoscintigraphy]

Two-compartment lymphoscintigraphy was developed to examine the sub- and epifascial lymphatics of the leg. Digital images were evaluated visually and semiquantitatively by calculating the uptake of activity within the lymph…

Bräutigam P et al. · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 ago 1997

Nível de evidência 3 de 5

Lipedema: a clinical entity distinct from lymphedema

In a review of 250 cases of lymphedema of the lower extremity, 9 patients were noted to share unique similarities in their history and physical findings. Although these patients had mild swelling in their pretibial areas and were…

Rudkin GH, Miller TA · Plastic and reconstructive surgery · 1 nov 1994

Nível de evidência 3 de 5

Noninvasive evaluation of the lymphatic system with lymphoscintigraphy: a prospective, semiquantitative analysis in 386 extremities

Lymphoscintigraphy has emerged as the diagnostic test of choice in patients with suspected lymphedema. To assess the lymphatic circulation of 386 extremities in 188 patients, we prospectively recorded a semiquantitative index of…

Cambria RA et al. · Journal of vascular surgery · 1 nov 1993

Nível de evidência 3 de 5

Swollen lower extremity: role of MR imaging

The authors assessed the use of magnetic resonance imaging in differentiating lymphedema, phlebedema, and lipedema of the lower limb. They examined 14 patients: five with lipedema, five with lymphedema, and four with phlebedema.…

Duewell S et al. · Radiology · 1 jul 1992

Nível de evidência 3 de 5

CT of swollen legs

The use of a single axial slice through the mid calf in the differential diagnosis of a swollen leg is described. This is a very simple quick non-invasive investigation. Venous obstruction results in an increase in the cross…

Vaughan BF · Clinical radiology · 1 jan 1990

Nível de evidência 3 de 5

[Lipedema: clinical and diagnostic criteria]

Lipedema is a common disease in the usual clinical practice. None organic description about the clinical symptoms and signs associated to this condition has been published. Fifty women with lipedema have been examined by the…

Bilancini S, Lucchi M, Tucci S · Angiologia · 1 jan 1990

Nível de evidência 3 de 5

[Lipedema]

Sem abstract disponível no PubMed.

Gregl A · Zeitschrift fur Lymphologie. Journal of lymphology · 1 dez 1987

Nível de evidência 3 de 5

The swollen leg

Systemic causes of leg edema include idiopathic cyclic edema, heart failure, cirrhosis, nephrosis and other hypoproteinemic states. Lymphedema may be primary, or secondary to neoplasm, lymphangitis, retroperitoneal fibrosis and,…

Young JR · American family physician · 1 jan 1977