ObjectivesLipedema is a progressive adipose disorder affecting women, with diagnosis often delayed due to symptom overlap and lack of validated tools. This study assesses the Turkish version of the Lipedema Screening…
BackgroundLipedema is a chronic pain disorder characterized by disproportionate adipose tissue accumulation and pain of the affected extremities. While medical compression therapy is recommended for pain reduction, evidence…
BackgroundLipedema is a chronic adipofascial disorder characterized by pain, edema and progressive functional impairment. Conservative treatment is widely recommended as first-line therapy, but evidence on its impact on…
Lipoedema and familial partial lipodystrophy (FPLD) are rare adipose tissue disorders frequently misclassified as common obesity. Clinical assessment and body mass index (BMI) alone may fail to capture regional fat distribution,…
BackgroundLipedema is a chronic condition that is increasingly being detected and gaining public awareness; however, strongly validated therapeutic options are lacking.ObjectivesGiven need for appropriate lipedema management…
Pain and reduced mobility are common among people living with lipoedema. While well-fitting compression garments can help alleviate these symptoms, poorly fitting garments may be ineffective and contribute to significant material…
Murden S, Welsh L, Macintyre L · British journal of community nursing · 26 out 2026
BackgroundChronic venous disorders and lipedema are complex and frequently underdiagnosed conditions characterized by heterogeneous clinical presentations, progressive tissue remodeling, and substantial variability in treatment…
To evaluate which factors are associated with change in lymphedema-specific quality of life (QoL) and relative volume difference in the maintenance phase after a multidisciplinary intensive treatment program in patients with…
Heroes A et al. · Lymphatic research and biology · 22 out 2026
The aim of this study was to characterize global scientific output on lipedema from 2000 to 2025 and identify emerging thematic trends, with emphasis on the emergence of immunological research. Publications indexed in Google…
Amato ACM, Amato JLS, Benitti DA · Revista da Associacao Medica Brasileira (1992) · 16 out 2026
ObjectivesLipedema is a chronic adipose tissue disorder characterized by disproportionate fat accumulation, lower extremity pain, functional impairment, and reduced quality of life. Although pain is a cardinal symptom, its…
Şahingöz Bakırcı E, Demir Karakılıç G · Phlebology · 16 out 2026
ObjectivesTo investigate the clinical and ultrasonographic changes associated with radial extracorporeal shock wave therapy (rESWT) in women with lipedema.MethodsThis prospective, single-arm study included 40 women with lipedema…
ObjectivesTo determine the prevalence of chronic venous insufficiency (CVI) in patients with lipedema, characterize venous reflux patterns and CEAP clinical classes, and evaluate associations with demographic and lipedema-related…
Gümrük Aslan S, Akın Yavuzel A, Gündoğdu O · Phlebology · 15 out 2026
ObjectiveThis study aimed to comparatively evaluate sleep quality in individuals with lipedema and healthy controls. In addition, the relationships between sleep quality and depression, anxiety, fatigue, and clinical parameters…
Kesiktaş N, Ersoy S, Şirin Ahısha B · Phlebology · 15 out 2026
Lipedema is a chronic disorder of adipose tissue marked by disproportionate fat accumulation in the extremities and persistent pain, which significantly impairs quality of life. Although liposuction has been adopted as a…
Halawani IR et al. · Aesthetic plastic surgery · 12 out 2026
There are no validated Norwegian disease-specific patient-reported outcome measures (PROMs) assessing quality of life (QoL) in females with lipedema, limiting evaluation of treatment effect in clinical practice and research. To…
Lundanes J et al. · Frontiers in global women's health · 9 out 2026
ObjectivesThis study aimed to determine the frequency of probable lipedema among women with lower extremity pain (LEP) using a validated screening questionnaire and to examine its associations with neuropathic pain (NP)…
Demir Karakılıç G et al. · Phlebology · 8 out 2026
Lipedema is a chronic adipose tissue disorder characterized by a disproportionate accumulation of painful subcutaneous fat on the extremities. Manual lymphatic drainage (MLD) is routinely used as therapeutic intervention, but its…
Nöll E et al. · Frontiers in cell and developmental biology · 7 out 2026
Background/Objectives: Lipedema is an adipose tissue disorder associated with body-related burden. This study compared orthorexic eating tendencies between women with and without lipedema and examined associations with body-shape…
Doran M, Zincirci DE, Şahan EG · Journal of clinical medicine · 4 out 2026
The aim of this study was to compare serum adiponectin, leptin, resistin, irisin, and galectin-3 levels between patients with lipedema and healthy controls, and to examine their relationship with subcutaneous adipose tissue…
Şahingöz Bakırcı E, Demir Karakılıç G, Kaymak E · Aesthetic plastic surgery · 28 set 2026
The clinical course of lipedema in women receiving hormonal treatment for concomitant estrogen-dependent gynecological disorders remains insufficiently characterized. This study aimed to describe gynecological and…
To compare the efficacies of extracorporeal shock wave therapy (ESWT) and complex decongestive therapy (CDT) in patients with lipedema. This randomized-controlled-study included 33 patients with lipedema, with 11 patients in each…
Türköz MD, Kasap Z, Keleş B · American journal of physical medicine & rehabilitation · 24 set 2026
This study aimed to compare 12-week changes in body composition and anthropometric parameters between standard-dose and lower-dose tirzepatide escalation regimens in women with lipedema, with particular emphasis on changes in fat…
Frederichi de Souza P, Patriani G, Ribeiro Pacheco CM · Cureus · 23 set 2026
BackgroundLipedema is a frequently misdiagnosed chronic condition that significantly impacts patients' quality of life. As artificial intelligence (AI)-based large language models (LLMs) become increasingly integrated into…
IntroductionAfter unification of diagnostic criteria for lipedema through guidelines and consensus documents as a fat-disproportion between abdomen and extremities with pain in the affected area, reduced by compression, expensive…
Individuals with lipoedema may experience negative impacts that are not often identified through current quality-of-life measures. The aim of this study was to explore the experiences of individuals living with pre-existing…
Stellmaker R et al. · International journal of qualitative studies on health and well-being · 18 set 2026
Low-carbohydrate diets (LCDs) have been suggested as a potential treatment option for females with lipedema, due to their superiority in reducing pain, possibly through improvements in insulin dynamics. The objective of this…
Lundanes J et al. · Frontiers in cell and developmental biology · 15 set 2026
The aesthetic-functional planning of the lower limbs is frequently conducted empirically, using idiosyncratic markings and limited standardization among specialists who work in this field. The absence of a common topographic…
Zeilmann E, Mello Netto BAS, Santos GS · Cureus · 12 set 2026
To comprehensively characterize pain in women with lipedema and evaluate its relationship with central sensitization, neuropathic pain characteristics, pain sensitivity, sleep quality, and quality of life. : A cross-sectional…
Orhan B et al. · Pain medicine (Malden, Mass.) · 12 set 2026
Lipedema is a chronic adipose tissue disorder that may involve the upper extremities, particularly in advanced disease stages, leading to pain, heaviness, and functional complaints. While liposuction is an established treatment…
Bruno A, Foti R · Aesthetic plastic surgery · 10 set 2026
This cross-sectional and descriptive study was conducted with 395 women to assess lipedema awareness, lipedema symptom levels, and the screening probability of lipedema. Data were collected using an Introduction Form, and the…
Şimşekli D, Yağcı Karamanlı H, Doğan C · Health care for women international · 8 set 2026
The Questionário de avaliação sintomática do lipedema (QuASiL - Lipedema Symptom Assessment Questionnaire) assesses 13 distinct inflammatory symptoms of lipedema, but whether these symptoms resolve and recur simultaneously or…
Amato ACM, Amato JLS, Benitti DA · Jornal vascular brasileiro · 7 set 2026
Lipedema is a chronic progressive condition affecting approximately 10% of women, characterized by disproportionate subcutaneous adipose tissue accumulation and pain in the lower extremities. Standardized assessment methods for…
Patton L et al. · Life (Basel, Switzerland) · 2 set 2026
Lipedema is a common, female-predominant disorder characterized by disproportionate, painful lower-limb adipose tissue, and it still lacks an objective biomarker, a disease-modifying therapy, or consensus on whether its core…
Amato AC, Amato JL, Benitti D · Cureus · 1 set 2026
Lipedema is a chronic adipose tissue disorder characterized by bilateral and symmetrical subcutaneous fat accumulation, predominantly affecting women. Because it is frequently confused with obesity and lymphedema, diagnosis may…
Yukselmis O et al. · Frontiers in medicine · 31 ago 2026
ObjectiveThis study aimed to investigate central sensitization (CS) in individuals with lipedema using pressure pain threshold measurements and to examine its relationship with clinical features, sonographic findings, body…
Yücel FN, Candan Z, Ata E · Phlebology · 18 ago 2026
Lipedema is a chronic medical condition primarily affecting women, characterized by bilateral, symmetrical, disproportionate fat deposition in the lower limbs, and sometimes arms and lower trunk. Pharmacological interventions…
Srinivasan A et al. · Obesity pillars · 14 ago 2026
Women with lipedema have an abnormal accumulation of adipose tissue that leads to pain and reduced quality of life (QoL). The impact of lipedema on body image and QoL remains largely unknown. The aim of this study is to explore…
Goodrose-Flores C, Björkhem-Bergman L · PloS one · 14 ago 2026
To evaluate ultrasonographic changes in lower extremity tendons and plantar fascia of patients with chronic edema and their relationship with edema volume, pain, function, and quality of life. This observational case-control…
Uğur AE, Soyupek F, Özçakar L · American journal of physical medicine & rehabilitation · 11 ago 2026
Lipedema is a chronic disorder characterized by excessive, bilateral, and symmetrical deposition of subcutaneous adipose tissue, predominantly in the lower extremities. Despite its prevalence, lipedema is frequently misdiagnosed…
Mortada H et al. · Plastic and reconstructive surgery. Global open · 10 ago 2026
Lipedema, a chronic condition primarily affecting women, is characterized by abnormal subcutaneous fat accumulation and swelling in the extremities (while sparing the hands, feet, and trunk). This disease is associated with…
Atabilen Pınar B et al. · Nutrition reviews · 1 ago 2026
Lipedema is a chronic progressive disease characterized by disproportionate and symmetric adipose tissue accumulation, predominantly affecting women, with upper extremity involvement (Type IV) in approximately 30% of cases. This…
We aimed to evaluate the association between pain, body mass index (BMI), clinical stage, and morphological type in women with lipedema, using segmental bioimpedance to correlate with clinical symptoms. We conducted a…
Pusic J, Mora S, Froes Meyer P · Journal of vascular surgery. Venous and lymphatic disorders · 24 jul 2026
Lipedema is a chronic disorder of subcutaneous adipose tissue characterized by disproportionate fat accumulation, pain, and progressive functional impairment, predominantly affecting women. Research remains fragmented across…
Viana DPdC, Invitti AL, Schor E · Frontiers in cell and developmental biology · 22 jul 2026
Lipedema is a chronic disorder that predominantly affects women and is characterized by abnormal subcutaneous adipose tissue accumulation, pain, and vascular dysfunction. However, reliable circulating biomarkers that reflect…
Kempa S et al. · Diseases (Basel, Switzerland) · 12 jul 2026
ObjectivesThe aim of this study was to compare metabolic status and biochemical indices associated with cardiovascular risk, including the triglyceride-glucose (TyG) index, triglyceride-glucose-body mass index (TyG-BMI), and…
Recent research suggests that body contouring surgeries may reduce benzodiazepine (BNZ) use in patients with anxiety or depressive disorders. This study explores whether similar benefits occur in women with lipedema-a chronic…
Bruno A, D'Antimi A · Aesthetic plastic surgery · 8 jul 2026
ObjectivesGenerative artificial intelligence (AI) models capable of producing photorealistic medical images are increasingly proposed for patient education, clinical illustration, and trainee instruction. However, their ability…
To examine the associations of ultra-processed food (UPF) consumption, dietary inflammatory index (DII), and Mediterranean diet adherence with pain severity, physical quality of life, body composition, and inflammatory markers in…
Lipedema is a chronic disorder characterized by disproportionate subcutaneous fat accumulation and pain, with an incompletely understood inflammatory component. It remains unclear whether this inflammatory profile is…
Şahingöz Bakırcı E, Demir Karakılıç G · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 30 jun 2026
Liposuction is a standard treatment for advanced-stage lipedema, often involving large volumes of tumescent fluid infiltration and aspiration. These shifts raise concerns about postoperative electrolyte imbalances, though…
Witulski C et al. · Aesthetic plastic surgery · 30 jun 2026
Lower leg lipodystrophy can be distressing to patients. Liposuction can contour the ankle, calf, and medial knee areas but requires the understanding of anatomy, thorough preoperative evaluation, and diligent postoperative care.…
Copeland-Halperin LR, O'Brien L, Copeland M · Aesthetic surgery journal. Open forum · 26 jun 2026
ObjectivesThere is a deficiency in awareness and knowledge of lipedema disease among the general public and healthcare professionals. This situation may lead patients to waste time on getting the correct diagnosis and treatment.…
Candan Z, Yücel FN, Ata E · Phlebology · 25 jun 2026
Lipedema is a chronic adipose tissue condition that primarily affects women. Despite increasing recognition of lipedema, the condition remains poorly understood and lacks standardized diagnostic criteria or confirmatory tests.…
Galia S et al. · Frontiers in global women's health · 24 jun 2026
Lipedema is a prevalent chronic condition in women, characterized by a painful and symmetrical accumulation of adipose tissue primarily in the lower limbs. Its diagnosis is based on specific clinical characteristics; however,…
Gursen C et al. · BMC women's health · 20 jun 2026
To compare central sensitization (CS), pressure pain threshold (PPT), and psychosocial factors between women with lipedema and healthy controls and to identify variables associated with CS in lipedema. In this cross-sectional…
Şirin Ahısha B et al. · Aesthetic plastic surgery · 17 jun 2026
Lipedema is a chronic condition that is often underdiagnosed. Clinical overlap with other disorders and the absence of specific diagnostic tools may delay diagnosis. This study aimed to translate and culturally adapt the lipedema…
Mansız-Kaplan B, Yaman A · Turkish journal of physical medicine and rehabilitation · 10 jun 2026
ObjectiveLipedema, which mainly affects women, is a chronic and progressive disorder characterized by abnormal adipose tissue accumulation in the limbs. Despite its clinical importance, research on lipedema remains limited.…
Çetin Duru E, Koçyiğit BF · Phlebology · 10 jun 2026
ObjectivesLipedema is a chronic disorder characterized by pain and disproportionate fat distribution, and its diagnosis is frequently overlooked. The aim of this study was to evaluate and compare the responses generated by…
BACKGROUND/AIM: Although various distinctive morphological features such as hyperproliferation of adipocytes, fibrosis, and inflammation have been described in the progression of lipedema, the underlying mechanisms of these…
Cagliyan Turk A, Erden E, Borman P · Lymphatic research and biology · 9 jun 2026
Lipedema is a chronic connective tissue disorder characterized by painful subcutaneous adipose accumulation, mainly in the lower extremities. Pain is a hallmark feature, yet its mechanisms remain poorly defined. Neuropathic…
Pervane S, Uzun Ö · Lymphatic research and biology · 8 jun 2026
Lipedema is a chronic adipose tissue disorder primarily affecting women, characterized by abnormal fat accumulation, pain, and reduced mobility. Its impact on sexual function remains underexplored. This study aimed to evaluate…
Recent studies have consistently shown that patients with lipedema are at a higher risk for depression and anxiety. The aim of this study is to identify the psychological factors associated with lipedema syndrome (LS) and their…
Seynhaeve B et al. · Lymphatic research and biology · 6 jun 2026
Lipedema is a chronic adipose tissue disorder with disproportionate fat accumulation in the extremities and is often misdiagnosed as obesity. Although women with lipedema appear to be metabolically distinct from body mass index…
Kempa S et al. · Frontiers in endocrinology · 5 jun 2026
Lipedema is a chronic adipose tissue disorder predominantly affecting women, often misdiagnosed as obesity or lymphedema. Emerging evidence points to microvascular dysfunction and chronic inflammation in its pathophysiology. This…
Yavas AD · Neuro endocrinology letters · 28 mai 2026
Lipedema is a chronic and progressive adipose tissue disorder that is often misdiagnosed and notoriously resistant to weight loss. Liposuction remains the most effective surgical treatment, but it requires precise technique to…
Munoz J, Fons S, Fabbri M · Aesthetic plastic surgery · 11 mai 2026
BackgroundLipedema is an adipose disorder associated with multiple impairments. Conservative treatments remain the mainstay of management, yet evidence regarding the effects of physical therapies on clinical, imaging, and body…
BackgroundLipedema is a chronic, progressive adipose tissue disorder affecting mainly women, characterized by bilateral, disproportionate fat accumulation in the lower extremities. The condition is often associated with pain,…
Ozbek IC, Kuculmez O, Dundar Ahi E · Phlebology · 8 mai 2026
Lipedema is a chronic adipose tissue disorder characterized by disproportionate fat deposition, primarily in the lower extremities, leading to pain, functional impairment, and reduced quality of life. While Power-Assisted…
Bruno A, Foti R · Aesthetic plastic surgery · 4 mai 2026
Lipedema is a chronic adipose tissue disorder characterized by abnormal and disproportionate fat accumulation in the extremities, leading to pain, edema, and functional impairment. Liposuction has become a central component of…
Amato FCM et al. · Aesthetic plastic surgery · 4 mai 2026
Lipedema is a chronic, progressive disorder of subcutaneous adipose tissue that mainly affects women. It is characterized by disproportionate fat hypertrophy, pain, bruising, and marked resistance to diet and exercise. Tumescent…
Bruno A, Foti R · Aesthetic plastic surgery · 4 mai 2026
Lipedema, a painful disease that almost exclusively affects women, leads to an excessive accumulation of subcutaneous adipose tissue, primarily in the extremities. Morphologically, it is characterized by hyperplasia and…
Steiner M et al. · Frontiers in cell and developmental biology · 1 mai 2026
Background/Objectives: Lipedema is a chronic adipose tissue disorder characterized by disproportionate fat accumulation, pain, microvascular dysfunction, and low-grade inflammation. Although low-carbohydrate, high-fat (LCHF)…
Lipedema is a painful subcutaneous adipose tissue (SAT) disorder that mainly affects women. Patients present fat accumulation in the limbs, especially in the legs. A pilot-controlled clinical trial was conducted on a sample of 18…
Úbeda-D'Ocasar E et al. · Journal of bodywork and movement therapies · 25 abr 2026
Infragluteal deformities are a challenging complication following liposuction, particularly when injury occurs to the fibrous osteocutaneous bands of the gluteal crease. Various surgical solutions have been proposed, including…
Mostofizadeh-Haghighi G et al. · Plastic and reconstructive surgery · 23 abr 2026
ObjectiveTo analyse and compare the prevalence of comorbidities associated with lipedema in Spanish women with that in the general population.MethodsA cross-sectional study was conducted using an anonymous online questionnaire…
Vaquero-Ramiro E et al. · Phlebology · 26 mar 2026
Lymphedema is a common, debilitating condition that challenges treatment efforts. The primary aim of treatment is to debulk the affected areas, providing relief without further damaging tissues or causing undesirable cosmetic…
Sollie M et al. · Aesthetic plastic surgery · 17 mar 2026
BACKGROUND/OBJECTIVES: Lipedema is a chronic and progressive adipose tissue disorder characterized by the abnormal accumulation of subcutaneous fat, predominantly in the legs and occasionally in the arms. The symptom that most…
Yaman A, Mansız-Kaplan B · International journal of obesity (2005) · 14 mar 2026
Despite ongoing research, the prevalence of lipoedema still relies on estimates, with figures in the recent literature ranging from 1% to 10%. Large-scale epidemiological studies on lipoedema are lacking. This retrospective…
Aitzetmüller-Klietz M et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 12 mar 2026
Background Lipedema is characterized by disproportionate gluteofemoral adiposity with anti-inflammatory properties. We hypothesized that this phenotype may confer immunological protection against T-helper 1 (Th1)-mediated…
Liposuction is the most frequently performed aesthetic surgical procedure on women worldwide. Thromboembolic events and fat embolisms are rare but typical complications of the procedure. To understand the associated risk factors,…
Edler C et al. · Forensic science, medicine, and pathology · 14 fev 2026
Lipedema is a chronic adipose tissue disorder predominantly affecting women and is frequently misclassified as obesity. While its physical manifestations are increasingly recognized, less attention has been paid to eating…
Kunzová M · Frontiers in global women's health · 13 fev 2026
ObjectivesThis study aimed to analyze the complex components of pain in lipedema and to evaluate correlations among key pain-related parameters, including intensity, hypersensitivity, catastrophizing, central sensitization, and…
Postoperative fibrosis is a frequent complication following liposuction for lipedema. Serrapeptase, a proteolytic enzyme with purported anti-inflammatory and antifibrotic effects, is used empirically, but robust evidence…
Bruno A, Saccoccio V · Aesthetic plastic surgery · 5 fev 2026
ObjectiveTo evaluate the educational quality, reliability, and transparency of YouTube™ videos on lipoedema, and to examine associations with uploader type and engagement metrics.MethodsOn 15 May 2025 we searched YouTube™ for…
Lipoedema is a condition of abnormal accumulation of painful adipose tissue, usually in the lower body of women. The disproportionate subcutaneous adipose tissue may negatively impact health-related quality of life (HRQoL). There…
Stellmaker R et al. · Journal of psychosomatic research · 2 fev 2026
lipedema is a chronic, progressive adipose disorder predominantly affecting women, characterized by painful, symmetrical subcutaneous fat accumulation, and typically resistant to lifestyle interventions. The pathophysiology of…
Santella B et al. · Journal of translational medicine · 24 jan 2026
BackgroundEndothermal ablation (ETA) is a well-established treatment for chronic venous insufficiency (CVI). However, its effectiveness in patients with concomitant lipedema remains poorly described. Given the distinct…
Reyes Valdivia A et al. · Phlebology · 19 jan 2026
Lipedema is a progressive subcutaneous adipose tissue disorder predominantly affecting women. Characterized by painful nodules and inflammation, it impairs mobility and quality of life. Traditional nonsurgical treatments…
Schwartz JS et al. · Plastic and reconstructive surgery. Global open · 16 jan 2026
Lipedema is a chronic condition characterized by abnormal subcutaneous fat accumulation, predominantly affecting women. It is associated with pain, swelling, reduced mobility, and psychological distress, all of which may limit…
Åström Malm I, Violasdotter Nilsson P, Hurtig-Wennlöf A · BMC women's health · 15 jan 2026
Lipedema predominantly affects women and is characterized by an abnormal distribution of adipose tissue, accompanied by pain or discomfort in affected areas. Despite growing awareness, inconsistent diagnostic criteria and…
Kruppa P et al. · Nature communications · 10 jan 2026
BackgroundLipedema is a chronic disorder involving abnormal accumulation of subcutaneous fat, primarily in the lower limbs. Liposuction is an effective treatment, but postoperative complications such as fluid retention and seroma…
Lipedema causes abnormal fat accumulation in the limbs, leading to pain, functional impairment, and body image disturbance. Nowadays, various liposuction techniques are available. The wet technique is increasingly being…
Thiry M et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 23 dez 2025
Background/Objectives: Lipedema is a chronic, progressive adipo-fascial disorder characterized by connective tissue dysfunction, fibrosis, microangiopathy, and adipose tissue proliferation. Although lipedema has traditionally…
Fiengo E, Sbarbati A · Journal of clinical medicine · 18 dez 2025
Lipedema is a chronic female disease, characterized by an excessive accumulation of subcutaneous adipose tissue in the limbs and is commonly mistaken for obesity, although the two conditions often coexist. Obesity is associated…
Lundanes J et al. · Frontiers in nutrition · 17 dez 2025
Lipedema is a chronic, progressive adipose tissue disorder that predominantly affects women and is characterized by disproportionate fat accumulation, pain, and edema. Hormonal fluctuations are frequently reported as triggers or…
Background/Objectives: Lipedema is a chronic disorder that affects almost exclusively women and is characterized by bilateral, symmetrical accumulation of subcutaneous fat, typically in the buttocks, hips, and lower limbs, and in…
Lipedema is an abnormal accumulation of subcutaneous fat that usually affects the lower extremities. Inflammation due to adipose tissue may negatively affect body structure and functions. This case-control study aimed to assess…
Haspolat M et al. · Physiotherapy theory and practice · 28 nov 2025
Lipedema is a relatively unknown condition, often leading to misdiagnosis and a lack of proper treatment. To explore the experiences of seeking healthcare support and treatment among women with a physician-verified diagnosis of…
Dahlberg J et al. · International journal of women's health · 27 nov 2025
BACKGROUND/OBJECTIVES: Lipedema is a chronic adipose tissue disorder characterized by disproportionate fat accumulation, pain, and low-grade systemic inflammation, primarily affecting women. This study investigated the…
Tel Adıgüzel K et al. · International journal of obesity (2005) · 27 nov 2025
Liposuction is effective for body contouring but may cause transient cutaneous sensory changes. In lipedema, therapeutic liposuction involves higher aspirate volumes, fibrotic tissue, and exposure of distal-leg zones at risk. We…
Bruno A, D'Antimi A · Aesthetic plastic surgery · 25 nov 2025
Aim Lipedema is a chronic, progressive disease that predominantly affects women and is strongly influenced by estrogen. Its onset or worsening is associated with hormonal periods such as puberty, pregnancy, pregnancy induction,…
This study aimed to evaluate the clinical efficacy of transfer energy capacitive and resistive (TECAR) therapy in females with Stage 2 lipedema, focusing on limb circumference, pain, functional status, and quality of life. A…
Uzun Ö et al. · Turkish journal of physical medicine and rehabilitation · 10 nov 2025
Lipedema is a chronic adipose tissue disorder characterized by abnormal fat accumulation, pain, often necessitating surgical intervention. While liposuction is the primary treatment to remove pathological fat, postoperative skin…
Bruno A, Cilluffo M · Aesthetic plastic surgery · 5 nov 2025
Background/Objectives: Lipedema is a chronic disorder characterized by disproportionate fat accumulation in the extremities, causing pain, bruising, and reduced mobility. When conservative therapy fails, liposuction is considered…
Sanktjohanser NA et al. · Journal of personalized medicine · 1 nov 2025
This study aims to present the results and limitations of surgery for lower limb lipoedema and lymphedema in a resource-limited surgical setting. This was a cross-sectional, analytical, prospective, in-hospital study covering 15…
Kibadi-Kapay A · The Pan African medical journal · 30 out 2025
Chronic edema in the lower extremities leads to significant negative effects on the quality of life, body image perception, satisfaction, self-confidence, and self-esteem of affected individuals. The aim of this study was to…
Ersoy S et al. · Revista da Associacao Medica Brasileira (1992) · 27 out 2025
Lipedema is a chronic and potentially progressive fat distribution disorder. Disease-related symptoms, such as pain and discomfort, can require surgical intervention when conservative therapies are exhausted. These…
Mostofizadeh-Haghighi G, Zaharie A, Ghods M · Aesthetic plastic surgery · 27 out 2025
Background/Objectives: Lipedema is a chronic, progressive disorder of the adipo-fascial tissue characterized by abnormal subcutaneous fat accumulation, inflammation, fibrosis, pain, and edema. Despite its considerable impact on…
Fiengo E, Sbarbati A · Journal of clinical medicine · 12 out 2025
We aimed to assess the sleep quality and the relationship between sleep and fatigue and quality of life in female lipedema patients. A total of 52 patients with lipedema (Group 1) and 40 healthy control subjects (Group 2) were…
Cagliyan Turk A et al. · Lymphatic research and biology · 7 out 2025
Background Lipedema is a chronic adipose tissue disorder affecting primarily women and is increasingly associated with immune dysregulation and intestinal permeability. Food-specific IgG testing has been explored in various…
Amato AC, Amato JS, Benitti D · Cureus · 3 out 2025
Lipedema is a chronic disease of subcutaneous tissue located on the extremities, whereas the distal parts are spared. It is almost completely restricted to women. The pathogenesis is poorly understood. Pain is the leading…
Wollina U, Goldman A, Levell NJ · Clinics in dermatology · 1 out 2025
Liposuction in lipedema is a safe and effective treatment, but there currently are no studies analyzing the individual complications of water-jet-assisted liposuction in lipedema or the impact of the cannula's design. The aim of…
Aitzetmüller-Klietz M et al. · Aesthetic surgery journal. Open forum · 26 set 2025
The etiology of lipoedema remains unclear, making diagnosis and treatment challenging. Current treatment primarily consists of general lifestyle recommendations, with effective self-management being essential for integrating…
Kloosterman LM et al. · Journal of multidisciplinary healthcare · 26 set 2025
Background: Lipedema, a chronic condition affecting mostly women, involves painful bilateral increase of subcutaneous adipose tissue. The societal impact of this disease is still poorly understood. This study aimed to validate…
Mahler J et al. · Lymphatic research and biology · 25 set 2025
Background/Objectives: Lipedema is a chronic adipose tissue disorder characterized by disproportionate fat accumulation and inflammation, predominantly affecting women. While recent evidence suggests a systemic pro-inflammatory…
Lipedema is a chronic disorder characterized by symmetrical and disproportionate fat accumulation, pain, and easy bruising, often resistant to conventional treatments. Functional dysmetria (FD), a maladaptive neuromotor response…
Lipedema is a chronic disorder of adipose tissue that predominantly affects women and is frequently misdiagnosed as obesity or lymphedema. Traditionally associated with the lower extremities, lipedema can also involve the…
Bruno A, Cilluffo M · Aesthetic plastic surgery · 12 set 2025
Lipedema is a chronic, progressive adipose connective tissue disorder characterized by symmetrical, disproportionate fat accumulation, typically affecting the lower extremities and arms, accompanied by pain, swelling, and a…
Al-Ghadban S et al. · Life (Basel, Switzerland) · 3 set 2025
To identify research priorities related to the diagnosis, treatment and management of lipoedema. This was a research question priority-setting that ensured the involvement of patients, relatives and healthcare professionals in…
ObjectiveThe incidence of lipedema is poorly described due to its confusion with lymphedema. Patient education is crucial for treatment and prevention strategies but also for improving healthcare outcomes. This study assessed and…
To determine the frequency of neuropathic pain in patients with lipedema and to assess the impact of neuropathic pain on quality of life and its correlation with clinical variables. The prospective, descriptive study included 150…
Erden E et al. · Irish journal of medical science · 11 ago 2025
Lipedema is a chronic condition characterized by excessive fat deposition in the hips, buttocks, and lower legs, significantly impacting quality of life. In Czechia, limited research exists on the relationship between lipedema…
Kunzová M, Lagová E, Keith L · Frontiers in global women's health · 24 jul 2025
ObjectiveTo assess the relationship between disease severity in lipedema and tissue stiffness measured using shear wave elastography (SWE) concerning pain threshold and quality of life as well as determine differences in…
BackgroundTo evaluate kinesiophobia and its relationship with disease-related characteristics and quality of life in lipedema patients.MethodsIn this descriptive case-control study, 40 lipedema patients and 40 participants in the…
Background: Lipedema is a chronic disease of subcutaneous adipose tissue that predominantly affects women and is frequently associated with endocrinopathies such as insulin resistance and obesity. Its pathogenesis is still…
Patton L et al. · Clinics and practice · 7 jul 2025
Lipedema is a chronic, progressive and underdiagnosed condition characterized by bilateral, disproportionate and painful subcutaneous fat accumulation in extremities. Key symptoms include pain, heaviness and easy bruising.…
Pereira N et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 3 jul 2025
Lipedema is an adipose tissue disorder involving mostly women. One of the most characteristic lipedema symptoms is painful accumulation of adipose tissue in lower and upper extremities leading to disproportion. Due to the…
Czerwińska M et al. · BMC women's health · 3 jul 2025
Lipedema often remains undiagnosed in patients with obesity, leading to mismanagement of treatment. Because of this, despite remarkable weight loss after bariatric surgery and decreases in hip and abdomen circumference, some…
Lipedema is a condition often mistaken for other causes of limb swelling including lymphedema and obesity. Lipedema may have a unique metabolic profile. Interrogation of the metabolome is a strategy that could reveal unique…
Alkhalfan F et al. · Obesity medicine · 23 mai 2025
Lipedema, a chronic condition affecting 11% of women, causes abnormal fat buildup in the lower limbs, leading to disproportionate body shape and functional problems. Often misdiagnosed, its cause is unclear, and conservative…
Hersant B et al. · Plastic and reconstructive surgery · 20 mai 2025
Lipedema is an adipose tissue disorder that principally affects women and is frequently misidentified as obesity or lymphedema. There have been relatively few studies that have precisely defined the pathogenesis, epidemiology,…
Mortada H et al. · Archives of plastic surgery · 15 mai 2025
Lipedema is a chronic disease in adipose tissue affecting women. The distinctive body appearance in lipedema, often mistaken for obesity, may be detrimental to social life. In our online cross-sectional survey study, conducted…
Falck J et al. · Health care for women international · 8 mai 2025
Lipedema is a painful disease of subcutaneous adipose tissue (SAT) in women. This study determined whether an advanced pneumatic compression device (APCD) improved lipedema SAT depth, swelling, and pain. Women with lipedema…
Herbst KL et al. · Life (Basel, Switzerland) · 30 abr 2025
Background: Pain is a prevalent symptom in patients with lipedema predominantly impacting the lower extremities. This study aimed to evaluate the relationship between 25-hydroxyvitamin D [25(OH)D] and vitamin B12 levels and…
Ozturk G et al. · Lymphatic research and biology · 16 abr 2025
Background: Bioimpedance spectroscopy (BIS) is commonly used for the detection and monitoring of lymphedema and potentially lipedema. BIS measures limb electrical resistance, which decreases with fluid accumulation in these…
Ward LC et al. · Lymphatic research and biology · 14 abr 2025
Lipoedema is a loose connective tissue disease primarily affecting women characterized by an abnormal build-up of painful fat in the legs and arms. In healthcare, lipoedema is often confused with obesity, and today, diagnostic…
Lipedema is a chronic disorder characterized by disproportionate fat accumulation in the extremities, predominantly affecting women. Unlike obesity, lipedema might be associated with a lower prevalence of metabolic alterations…
Lipedema is a chronical progressive disease mostly found in women, characterized by an unproportional increase of fat in the limbs and pain. So far mental perspectives are not acceptably resolved. This study examines patients'…
Kreidel Y et al. · Psychotherapie, Psychosomatik, medizinische Psychologie · 3 abr 2025
IntroductionLipedema is a chronic and progressive adipose tissue disorder that predominantly affects women. However, despite its high prevalence and severe negative impact on quality of life, it remains significantly…
The psychosocial and mental health challenges of living with lipoedema are well documented and may influence motivation and confidence with self-care. This article provides a background to the condition, reviewing evidence…
Williams A, McKain L · British journal of community nursing · 1 abr 2025
Lipalgia syndrome, also known as lipoedema, is a chronic condition involving disproportionate adipose tissue accumulation with pain and tenderness. This study explores the perceptions, challenges and needs of lymphoedema…
Cooper G et al. · British journal of community nursing · 1 abr 2025
To explore the experiences of sexual health and intimate relationships in women with lipedema. A qualitative interview study. Sixteen women with lipedema recruited from a national lipedema association group in Sweden…
Falck J et al. · Journal of advanced nursing · 26 mar 2025
Background: Lipedema is an adipose tissue disorder in women, with an abnormal fat deposition in lower limbs and occasionally upper limbs. The condition is characterized by pain, bruising, heaviness, and mobility impairment.…
Río-González Á et al. · Journal of clinical medicine · 21 mar 2025
Lipedema is a chronic condition involving abnormal fat deposition in the lower limbs, often underdiagnosed, and poorly understood. We examined the epidemiological and clinical characteristics of a large patient cohort in…
Lipedema is a chronic disease in females characterized by pathologic subcutaneous adipose tissue expansion and hitherto remains without druggable targets. In this observational study, we investigated the molecular hallmarks of…
Straub LG et al. · Metabolism: clinical and experimental · 15 mar 2025
Introduction: Lymphedema and lipedema are chronic conditions significantly impacting psychosocial status and quality of life (QOL). However, comparative studies on depression, life satisfaction, functional status, and QoL in…
Yaman A et al. · Lymphatic research and biology · 13 mar 2025
This study aimed to evaluate adipose tissue of lipedema patients. Gluteo-femoral (affected area) and interscapular (nonaffected area) adipose tissue from 10 lean patients affected by lipedema stage 1 to 2 was studied and compared…
Michelini S et al. · Obesity (Silver Spring, Md.) · 12 mar 2025
Lipedema is a lipodystrophic disease that is typically characterized by a marked increase in lower-body subcutaneous adipose tissue that is purported to have increased inflammation and fibrosis, have impaired…
The cause of lipoedema remains unclear, and the condition is currently incurable. Effective self-management is therefore essential for coping with its physical and psychological impacts and the necessary lifestyle adjustments.…
Kloosterman LM et al. · Journal of multidisciplinary healthcare · 27 fev 2025
Discriminating lipedema from lymphedema becomes challenging in the absence of a pathognomonic test. The objective was to find the best manifestations that discriminate between lipedema and lymphedema and to build a diagnosis…
Forner-Cordero I, Muñoz-Langa J, Morilla-Bellido L · International angiology : a journal of the International Union of Angiology · 26 fev 2025
Lipedema is considered an inflammation-related disease, and low-carbohydrate ketogenic diets may help reduce inflammation. However, no randomized controlled trials have investigated the effect of a low-carbohydrate ketogenic diet…
Lundanes J et al. · Current developments in nutrition · 20 fev 2025
The aim of this study was to explore the functioning of people with lipoedema from their perspective. This was a qualitative study following a phenomenological perspective using individual in-depth interviews with a convenience…
Kloosterman LM et al. · International journal of qualitative studies on health and well-being · 20 fev 2025
ObjectivesTo evaluate the presence of lipedema and lipedema-related factors in fibromyalgia patients.MethodsThe study included 100 female patients over the age of 18 who met the fibromyalgia diagnostic criteria. The patients were…
Bolkan Günaydın E et al. · Phlebology · 14 fev 2025
Lipedema, historically underrecognized, has recently gained attention due to advancements in research and growing public awareness. The Brazilian Consensus Statement on Lipedema, developed by the Brazilian Society of Angiology…
Amato ACM et al. · Jornal vascular brasileiro · 10 fev 2025
It is not yet known whether lipedema is a progressive chronic disease or not. The aim of this paper is to describe the long-term changes in the volume of the lower limbs. The primary endpoint of this prospective cohort study of…
Forner-Cordero I, Muñoz-Langa J · Vascular medicine (London, England) · 20 jan 2025
Background: Despite its estimated high prevalence among women and increasing awareness, lipedema remains under-investigated. Ignoring its debilitating nature, surgical treatment for this condition is frequently covered by health…
Aitzetmüller-Klietz M et al. · Journal of clinical medicine · 6 jan 2025
Background: Lipedema is a chronic condition characterized by abnormal deposition of subcutaneous adipose tissue, leading to pain. The lack of internationally recognized diagnostic criteria complicates the characterization of…
Bettariga F et al. · Lymphatic research and biology · 24 dez 2024
This study addresses the diagnostic challenges of identifying lymphoedema in patients with lipoedema using lymphoscintigraphy. Overdiagnosis of lymphoedema in this patient population is frequent and may result in reduced proposed…
Background: Lipedema is a subcutaneous adipose tissue disorder mainly affecting women. Its progressive nature often requires high-volume liposuction for efficient pain reduction. However, aspiration volumes of more than 5 L…
Flores T et al. · Journal of clinical medicine · 19 dez 2024
This study explored experienced weight stigma, internalised weight bias and depressive symptom severity in lipoedema, a chronic health condition that primarily affects women and involves painful and disproportionate adipose…
Clarke C, Kirby JN, Best T · Clinical obesity · 14 dez 2024
Lipedema is characterized by the painful abnormal deposition of adipose tissue in the lower limbs and is often misdiagnosed as obesity. Considering the numerous bothersome physical symptoms of lipedema, women with lipedema may…
Chachaj A et al. · Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 1 dez 2024
Lymphoedema and lipoedema can present similarly however have different aetiologies and should be considered as distinct clinical entities. Pain is a distinguishing feature of lipoedema. Liposuction can be used in both conditions…
Hilder KR, Munnoch DA · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 28 nov 2024
Lipedema is a disease typically affecting women with a symmetrical, painful fat distribution disorder, which is hypothesized to be caused by impaired adipogenesis, inflammation, and extracellular matrix remodeling, leading to…
Streubel MK et al. · Plastic and reconstructive surgery. Global open · 8 nov 2024
Lipedema is a common, yet underdiagnosed, subcutaneous adipose tissue (SAT) disorder. The main characteristics are SAT expansion in the lower extremities and arms, pain, and tenderness to palpation. It remains unknown if a…
Lundanes J et al. · Frontiers in nutrition · 7 nov 2024
Lipedema is a chronic disorder affecting women with a 10% incidence worldwide. It is often confused with obesity. This study was undertaken to study microRNAs in lipedema tissue assessed by direct hybridization using the robust…
Cione E et al. · Current issues in molecular biology · 25 out 2024
Lipedema is a chronic fat disorder characterized by disproportionate fat deposition in the lower limbs, leading to pain, mobility issues and reduced health related quality of life (HRQoL).There is growing evidence that…
The treatment of lipedema remains challenging, largely due to widespread misconceptions. Selecting the appropriate treatment method necessitates the use of accurate outcome measures. This study aims to evaluate the effectiveness…
Czerwińska M et al. · Life (Basel, Switzerland) · 22 out 2024
Lipoedema is a congenital fat distribution disorder. It leads to a pathological increase in adipose tissue due to a hypertrophy and hyperplasia of the adipocytes. Currently, the disease affects approximately 10% of women. A…
Hoffmann J et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 13 out 2024
The goal of this study was to test the hybrid technique of combined tumescent liposuction and surgical excision in patients with advanced lipolymphedema of the thigh after compression therapy as a gold standard for treatment.…
ElKiran YM et al. · Journal of vascular surgery. Venous and lymphatic disorders · 10 out 2024
Background: Lipedema is a disease characterized by an increase in extracellular fluid. In these patients, the increase in the amount of extracellular fluid may accelerate the progression of the disease. The aim of this study is…
Esmer M, Schingale FJ · Lymphatic research and biology · 9 out 2024
Allert S · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 1 out 2024
AimThis study aimed to monitor public interest in information related to Lipedema and examine potential temporal, seasonal, and income-related trends that may impact public interest.Material - MethodsA dataset was created using…
Erden Y, Temel MH, Bağcıer F · Phlebology · 24 set 2024
Gestrinone (R-2323), or ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group more commonly used as an oral, intravaginal, or subcutaneous implant for the treatment of endometriosis, contraception, and…
Renke G et al. · Pharmaceuticals (Basel, Switzerland) · 22 set 2024
Lower limb swelling presents a diagnostic challenge with diverse causes, including well-known issues like venous insufficiency and lymphedema, and less-understood conditions like lipedema. Lipedema, involving abnormal fat…
Alosaimi K, Mortada H, Alshomer F · Plastic and reconstructive surgery. Global open · 18 set 2024
Liposuction for stage III lipoedema is a guideline-based but also time-consuming treatment, which can be carried out under specific conditions at the expense of the German statutory health insurance companies (SHI) based on a…
Moog P et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 16 set 2024
Liver cirrhosis is a complex disease that may result in increased morbidity and mortality following bariatric surgery (BS). This study aimed to explore the outcome of BS in patients with unexpected cirrhosis, focusing on…
Sun X et al. · Liver research (Beijing, China) · 26 ago 2024
Background Lipedema is a chronic, incurable disorder characterized by painful fat accumulation in the extremities. While the application of liposuction in lipedema management has become increasingly popular, the safety and…
Mortada H et al. · Archives of plastic surgery · 6 ago 2024
Body composition (BC) measured by DXA differs between devices. We aimed to compare regional and total BC measurements assessed by the Hologic Horizon A and the GE Lunar iDXA devices; to determine device-specific calibration…
We evaluated the effect of compression leggings with micromassage in association with physical activity on women with lipedema, not previously treated and without recent changes in body weight. The treatment resulted in an…
Ricolfi L et al. · Life (Basel, Switzerland) · 8 jul 2024
Lipedema is the progressive symmetrical deposition of subcutaneous fat and fluid in the lower body, ordinarily sparing the trunk, upper limbs, face, and neck. It may follow an autosomal dominant inheritance pattern. The gold…
Bejar-Chapa M et al. · Plastic and reconstructive surgery. Global open · 2 jul 2024
Background: Despite its increasing incidence and prevalence throughout Western countries, lipedema continues to be a very enigmatic disease, often misunderstood or misdiagnosed by the medical community and with an intrinsic…
Lipoedema is a painful adipose tissue disorder, affecting the limbs of women, that is resistant to diet and exercise. The purpose of the study was to evaluate the retrospective health-related quality-of-life (HRQoL) outcomes for…
Lipedema and lymphedema are physically similar yet distinct diseases that are commonly misdiagnosed. We previously reported that lipedema and lymphedema are associated with increased risk for venous thromboembolism (VTE). The…
TRPV4 channels are critical regulators of blood vascular function and have been shown to be dysregulated in many disease conditions in association with inflammation and tissue fibrosis. These are key features in the…
Schulz ME et al. · bioRxiv : the preprint server for biology · 23 mai 2024
The role of artificial intelligence (AI) in healthcare is evolving, offering promising avenues for enhancing clinical decision making and patient management. Limited knowledge about lipedema often leads to patients being…
Leypold T et al. · Life (Basel, Switzerland) · 20 mai 2024
Background: Lipedema is a subcutaneous adipose tissue disorder characterized by increased pathological adipocytes mainly in the extremities. Vitamin D is stored in adipocytes, and serum levels inversely correlate with BMI. As…
Flores T et al. · Journal of clinical medicine · 11 mai 2024
Lipedema is a chronic, idiopathic, and painful disease characterized by an excess of adipose tissue in the extremities. The goal of this study is to characterize the gene expression of estrogen receptors (ERα and ERβ), G…
This study aimed to develop a novel predictive equation for calculating resting metabolic rate (RMR) in women with lipedema. We recruited 119 women diagnosed with lipedema from the Angiology Outpatient Clinic at Wroclaw Medical…
Lipedema is a widespread severe chronic disease affecting mostly women. Characterized by painful bilateral fat accumulation in extremities sparing hands and feet, objective measurement-based diagnosis is currently missing. We…
The 11th annual National Lymphoedema Conference, organised by the British Journal of Community Nursing in association with the British Lymphology Society and Lipoedema UK, was hosted at the America Square Conference Centre,…
Hashimi S, Rajagopalan U · British journal of community nursing · 1 abr 2024
The Health and Safety Execultive lymphoedema model of care was published in 2018 highlighting the lack of dedicated lymphoedema services in Ireland. This led to the introduction of a proof-of-concept primary care specialist…
Morris K et al. · British journal of community nursing · 1 abr 2024
Lipoedema is the disproportionate accumulation of adipose tissue in the lower body, often associated with hormonal changes in women. Lipoedema is commonly misdiagnosed as lymphoedema or obesity due to similarities in appearance.…
Stellmaker R et al. · Clinical obesity · 28 mar 2024
Lower extremity swelling may be broadly characterized as due to edema, lymphedema, or lipedema. Differentiation between these three conditions is important for providing appropriate treatment. This review analyzes and compares…
Body mass index (BMI) is seen as a predictor of cardiovascular disease (CVD) in lipedema patients. A valid predictor of CVD is increased aortic stiffness (IAS), and previous research described IAS in lipedema. However, it is not…
Mahlmann A et al. · Sensors (Basel, Switzerland) · 5 mar 2024
Lipedema is a progressive connective tissue disease with enlargement of adipose tissue, fibrosis, fluid collection, and dermal thickening. Herein, we present a case of lipedema associated with skin hypoperfusion and ulceration in…
Alshomer F et al. · Archives of plastic surgery · 4 mar 2024
Correction to: Eur Rev Med Pharmacol Sci 2023; 27 (6 Suppl): 127-136-DOI: 10.26355/eurrev_202312_34697 After publication and following some post-publication concerns, the authors have applied the following corrections to the…
Kaftalli J et al. · European review for medical and pharmacological sciences · 1 mar 2024
Background: Lipedema is a progressive condition involving excessive deposition of subcutaneous adipose tissue, predominantly in the lower limbs, which severely compromises quality of life. Despite the impact of lipedema, its…
Morgan S et al. · Lymphatic research and biology · 26 fev 2024
Background: Complex decongestive therapy (CDT) is the standard and basic therapy for lymphedema. The central component of CDT is manual lymphatic drainage (MLD). In addition to CDT, other measures such as intermittent pneumatic…
Schiltz D et al. · Journal of clinical medicine · 23 fev 2024
We conducted a comparative study involving 39 female patients with lipedema and group-matched controls at a ratio of 1:5. The primary survey tool was the German Health Update (GEDA 2019/2020-EHIS) questionnaire, which was…
Kempa S et al. · Life (Basel, Switzerland) · 22 fev 2024
The study examines, for the first time, the impact on quality of life after liposuction for lipoedema. The influence of aesthetic plastic interventions and their effects on treatment outcomes has been a major focus of our…
Klöppel M et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 10 fev 2024
Patients with lymphedema and lipedema share physical exam findings that may lead to misdiagnosis. Poor mobility is common in patients with obesity and patients with lymphedema and lipedema. This may constitute a risk factor for…
Khalid MU et al. · Vascular medicine (London, England) · 1 fev 2024
We analyzed the medical condition of 360 women affected by lipedema of the lower limbs in stages 1, 2, and 3. The data were assessed for the whole population and compared between different clinical stages, distinguishing between…
Patton L et al. · International journal of molecular sciences · 27 jan 2024
The Editor in Chief and the Publisher are issuing an expression of concern to alert readers to the fact that the Special Issue titled "Omics sciences in the personalization of diagnosis and therapy" and, in particular, the…
Listed NA · European review for medical and pharmacological sciences · 1 jan 2024
Lipedema is a chronic disease marked by symmetric enlargement of painful nodular and fibrotic adipose tissue, predominantly affecting the limbs. Since there is no specific test or biomarker for this condition, years often pass…
Kempa S et al. · Clinical hemorheology and microcirculation · 1 jan 2024
Symmetrical bilateral lower extremity edema (BLEE) needs to be treated effectively. Finding the cause of this condition increases the success of treatment. Fluid increase in the interstitial space (FIIS) is always present as a…
Ceylan S, Yilmaz N · Current medical imaging · 1 jan 2024
To describe and analyse experiences of living with lipedema. Methods: Individual, semi-structured interviews with a purposive sample of 12 women diagnosed with lipedema and analysed by qualitative content analysis utilizing an…
Dahlberg J et al. · International journal of qualitative studies on health and well-being · 30 dez 2023
Background/Aim: The aim of this study was to determine the frequency of fibromyalgia syndrome (FMS) in patients with lipedema and to evaluate the effects of FMS on anxiety, depression, and quality of life (QoL) in this patient…
Cagliyan Turk A et al. · Lymphatic research and biology · 22 dez 2023
Lipedema is a chronic condition characterized by disproportionate and symmetrical enlargement of adipose tissue, predominantly affecting the lower limbs of women. This study investigated the use of metabolomics in lipedema…
Kempa S et al. · International journal of molecular sciences · 13 dez 2023
To evaluate the effects of the venous insufficiency (VI) or lipedema on the symptoms, functions, and quality of life (QoL) of patients with knee osteoarthritis (OA). 96 patients with stage 3/4 knee OA were included in the study.…
To quantify and compare associations and relationships between self-rated and tested assessments of mainly mobility-related physical function in different diagnoses. Six longitudinal cohort studies before and after inpatient…
Benz T et al. · Journal of rehabilitation medicine · 4 dez 2023
Lipedema is an autosomal dominant genetic disease that mainly affects women. It is characterized by excess deposition of subcutaneous adipose tissue, pain, and anxiety. The genetic and environmental etiology of lipedema is still…
Kaftalli J et al. · European review for medical and pharmacological sciences · 1 dez 2023
Lipedema is a chronic inflammatory subcutaneous adipose-rich connective tissue disease affecting millions of women worldwide. Disproportionate fat accumulation on the extremities characterized by heaviness, tenderness, and…
Wright T et al. · Plastic and reconstructive surgery. Global open · 30 nov 2023
This study aimed to assess the potential benefits of a low-carbohydrate, high-fat (LCHF) diet on body composition, leg volume, and pain reduction in women with lipedema compared to overweight or women with obesity. The study…
Jeziorek M et al. · Journal of obesity · 18 nov 2023
Lipedema is a chronic disorder that mainly affects women. It is often misdiagnosed, and its etiology remains unknown. Recent research indicates an accumulation of macrophages and a shift in macrophage polarization in lipedema.…
We aimed to model total charges for the most prevalent multimorbidity combinations in the USA and assess model accuracy across Asian/Pacific Islander, African American, Biracial, Caucasian, Hispanic, and Native American…
This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) is intended to provide clinicians with an overview on obesity, thrombosis, venous disease, lymphatic disease, and lipedema. The scientific support for this…
National survey data exploring the patient experience with lipedema are lacking. We conducted national surveys from 2016 to 2022 of women with lipedema as well as female controls. Surveys collected information on symptomatology,…
Aday AW et al. · Vascular medicine (London, England) · 16 out 2023
Background: Lipedema is a chronic and progressive disease. Many complications can occur if the disease is not treated. The most important of these complications is lipedema with secondary lymphedema. There are very few…
Esmer M, Schingale FJ · Lymphatic research and biology · 3 out 2023
Lipedema is a connective tissue disorder characterized by increased dilated blood vessels (angiogenesis), inflammation, and fibrosis of the subcutaneous adipose tissue. This project aims to gain insights into the angiogenic…
Al-Ghadban S et al. · International journal of molecular sciences · 1 set 2023
Lipedema, also known as lipohyperplasia dolorosa (LiDo), is a painful condition affecting women, causing a disproportionate accumulation of subcutaneous adipose tissue in the extremities. It carries a lower risk of diabetes and…
Brenner E et al. · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 30 ago 2023
Lipoedema is an adipose tissue disorder that is still not fully understood. The primary purpose of this study is to explore the state of knowledge and understanding of lipoedema among Polish women. The secondary aim is to…
Hansdorfer-Korzon R et al. · BMC women's health · 29 ago 2023
The pathologic features of fatty tissue in lipedema are often challenging to diagnose, thus allowing for variable bias and leading to underdiagnosis. Lipedema is a disease that is currently little known worldwide, but it…
Carballeira Braña A, Poveda Castillo J · International journal of environmental research and public health · 25 ago 2023
In recent years, the use of the ketogenic diet as a proper nutritional treatment for lipedema has been hypothesized in the literature. This is the first clinical study evaluating the ketogenic diet and carboxytherapy in lipedema…
Lipedema is a widespread disease with painful accumulations of subcutaneous fat in the legs and arms. Often, obesity co-occurs. Many patients suffer from impairment in mobility and mental health. Obesity and mental health in turn…
Aitzetmüller-Klietz M et al. · Journal of clinical medicine · 16 ago 2023
Background: The presence of edema in patients with lipedema has been investigated in many studies. However, no study has been found that examines the amount of intracellular (ICF) and extracellular fluid (ECF) in these patients…
Esmer M, Schingale FJ · Lymphatic research and biology · 2 ago 2023
Lipedema is a painful subcutaneous adipose tissue (SAT) disease characterized by adipocyte hypertrophy, immune cell recruitment, and fibrosis in the affected areas. These features are thought to contribute to the development and…
Kruppa P et al. · Frontiers in immunology · 28 jul 2023
The billing of lipoedema treatment in Germany has come to be heterogeneous. This is due to the decision of the Federal Joint Committee ("Gemeinsamer Bundesausschuss", G-BA) to acknowledge lipoedema stage III as a treatment to be…
Motamedi M et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 20 jul 2023
Lipedema, as a disabling and consequential disease, is gaining more awareness due to its potential omnipresence. Patients suffering from lipedema show a characteristic painful display of symmetric accumulations of adipose tissue.…
Kirstein F et al. · Healthcare (Basel, Switzerland) · 13 jul 2023
Objective The aim of this study is to assess the prevalence of HLA-DQ2 and HLA-DQ8 in women diagnosed with lipedema. Methods Leukocyte histocompatibility antigen (HLA) tests of 95 women diagnosed with lipedema were analyzed using…
A large and growing body of research suggests that the skin plays an important role in regulating total body sodium, challenging traditional models of sodium homeostasis that focused exclusively on blood pressure and the kidney.…
Chattopadhyay A et al. · Clinical and experimental dermatology · 7 jul 2023
Lower limb lipoedema is a chronic condition of the adipose connective tissue of the skin that affects women. Its frequency is not well known, hence the main objective of this study. Retrospective analysis of the records of…
Rastel D, Urbinelli R · Journal de medecine vasculaire · 24 jun 2023
Aesthetic surgery training renders to be challenging to acquire sufficient hands-on experience during residency. To resolve this problem, the "Munich Model" was established in our clinic: Senior residents perform aesthetic…
This is a retrospective analysis of all lipedema patients treated by tumescent liposuction at our department in the years 2007-2021: We performed 519 liposuctions in 178 patients with a mean age of 45 ± 15.5 years. By the stage…
Kodim A, Wollina U · Wiener medizinische Wochenschrift (1946) · 14 jun 2023
The aim of this study was to evaluate alterations in blood parameters after a low-carbohydrate high-fat (LCHF) diet in women with lipedema in comparison to overweight or obese women. A total of 115 women were classified into two…
Lipedema is a painful subcutaneous adipose tissue (SAT) disease involving disproportionate SAT accumulation in the lower extremities that is frequently misdiagnosed as obesity. We developed a semiautomatic segmentation pipeline…
Taylor SL et al. · Journal of medical imaging (Bellingham, Wash.) · 15 mai 2023
Lipedema is a common chronic fat distribution disorder often aligned with pain and reduced quality of life affecting 6-10% of the female population. Although lipedema has acquired more scientific attention in the last decade,…
Seefeldt T et al. · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 15 mai 2023
Lipedema, lipohypertrophy and secondary lymphedema are three conditions characterized by disproportionate subcutaneous fat accumulation affecting the extremities. Despite the apparent similarities and differences among their…
von Atzigen J et al. · International journal of molecular sciences · 20 abr 2023
Introduction: Lipedema is a bilateral enlargement of the legs due to abnormal depositions of subcutaneous fat. Recent studies using lymphoscintigraphy documented that lipedema associates with lymphatic alterations. It is still…
Chachaj A et al. · Frontiers in physiology · 10 abr 2023
Lipoedema is an adipose tissue disorder almost exclusively affecting women. Evidence shows lipoedema is both poorly recognised and misdiagnosed which results in many women struggling to get a diagnosis and to gain access to…
Warrilow M · British journal of community nursing · 1 abr 2023
Background: To define the usefulness of three-dimensional (3D) ultrasound diagnostics for lipedema. Methods and Results: In this study, starting in May 2021, it was decided to apply 3D ultrasound diagnostics in the evaluation of…
Cestari M · Lymphatic research and biology · 28 mar 2023
Expert representatives from 11 professional societies, as part of an autonomous work group, researched and developed appropriate use criteria (AUC) for lymphoscintigraphy in sentinel lymph node mapping and lymphedema. The…
Donohoe KJ et al. · Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 23 mar 2023
Lipedema, diagnosed most often in women, is a progressive disease characterized by the disproportionate and symmetrical distribution of adipose tissue, primarily in the extremities. Although numerous results from in vitro and in…
Ernst AM et al. · Plastic and reconstructive surgery · 14 mar 2023
Introduction The current study aimed to investigate the overlap between symptoms of lipedema and attention-deficit/hyperactivity disorder (ADHD). Lipedema is a condition that causes abnormal fat accumulation and inflammation in…
Lipoedema is characterized by disproportionate painful fat accumulation mostly in the lower limbs. The presence of lymphoedema in lipoedema remains controversial. This study aimed to assess the presence or absence of lymphoedema…
The typical therapy in lymphology is conservative. However, reconstructive and resective treatments for primary and secondary lymphoedema as well as resective procedures for lipohyperplasia dolorosa (LiDo) "lipedema" have been…
Cornely ME · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 1 fev 2023
Lipoedema is a painful non-pitting diffuse "fatty" swelling, usually confined to the legs, that occurs mainly in women. This scoping review aimed to provide an overview of the available research on the functioning of people with…
Kloosterman LM et al. · International journal of environmental research and public health · 21 jan 2023
Lipedema is a chronic adipose tissue disorder affecting approximately 11% of women worldwide. The illness is often misdiagnosed as obesity, and because of this, women often struggle in meetings with healthcare providers. Few…
Christoffersen V, Tennfjord MK · International journal of environmental research and public health · 20 jan 2023
Background: An adequate dietary energy supply is particularly important in patients with lipedema as it promotes weight and fat loss. Accurate estimation of resting metabolic rate (RMR) allows implementing a proper calorie…
Jeziorek M et al. · Lymphatic research and biology · 20 jan 2023
(1) Background: Although lipedema has gained more interest among researchers, specific treatment methods are still unknown. This study aims to identify the effects of compression therapy combined with exercises compared to…
Czerwińska M et al. · International journal of environmental research and public health · 4 jan 2023
Lipedema is usually thought of as a dis-ease of women. Potentially diagnostic comparative data is needed between patients with lip-edema and those with lower limb lymphedema (LLL). Since there is no gold standard to diagnose…
Lipedema, a chronic disease characterized by excessive fatty tissue deposition in the hips, buttocks, and lower legs, significantly negatively impacts the quality of life of those affected. This disease, which almost exclusively…
The aim of this pilot study was to investigate the effects of defocused and radial shock wave therapy, mesotherapy, and kinesio taping on pain, circumferences of lower limbs, echographic/ elastosonographic pattern of subcutaneous…
Mast cells are immune cells that mediate hypersensi-tivity and allergic reactions in the body, secreting histamine and other inflammatory molecules. They have been associated with different inflammatory conditions such as obesity…
Bonetti G et al. · La Clinica terapeutica · 1 jan 2023
There are both conservative and surgical treatment options for Lipohyperplasia dolorosa (LiDo). A procedure that has been established since 1997 is the surgical treatment through Lymphological Liposculpture according to Cornely™.…
Cornely M, Gensior M · Dermatologie (Heidelberg, Germany) · 22 dez 2022
Liposuction plays an important role as a surgical treatment option for lipoedema. This article serves to critically review the evidence in the literature, as well as explain the differences between the lipoedema population…
Dancey A et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 21 dez 2022
Lipedema is a chronic and progressive adipose tissue disorder, characterized by the painful and disproportionate increase of the subcutaneous fat in the lower and/or upper extremities. While distinct immune cell infiltration is a…
Wolf S et al. · Frontiers in immunology · 20 dez 2022
Lipoedema is a chronic disease in adipose tissue that almost exclusively affects women during periods of hormonal alterations. Its main symptoms include an abnormal accumulation of subcutaneous fat in the buttock, hips, and legs,…
Lipedema is a common disorder characterized by excessive deposition of subcutaneous adipose tissue (SAT) in the legs, hips, and buttocks, mainly occurring in adult women. Although it appears to be heritable, no specific genes…
Klimentidis YC et al. · European journal of human genetics : EJHG · 16 nov 2022
Lipedema may be considered a model for healthy expandability of subcutaneous adipose tissue (SAT). This condition is characterized by the disproportional and symmetrical SAT accumulation in the lower-body parts and extremities,…
Nankam PAN et al. · Frontiers in endocrinology · 31 out 2022
Lipedema is a poorly known condition. Diagnosis is based almost exclusively on clinical criteria, which may be subjective and not always reliable. This study aimed to investigate regional body composition (BC) by dual-energy…
Lipedema is a chronic and progressive adipose tissue disorder that causes significant morbidity and negatively influences mental health and quality of life, and increases the risk of depression, anxiety, and eating disorders. One…
Al-Wardat M et al. · International journal of environmental research and public health · 21 out 2022
Lipoedema is a chronic adipose tissue disorder mainly affecting women, causing excess subcutaneous fat deposition on the lower limbs with pain and tenderness. There is often a family history of lipoedema, suggesting a genetic…
The aim of this study was to define outcomes after total knee arthroplasty (TKA) in lymphoedema and lipoedema patients managed by a multidisciplinary team and daily compression bandaging. A retrospective study was performed in a…
Granger L et al. · International orthopaedics · 8 set 2022
Lipedema is a disease with abnormally increased adipose tissue deposition and distribution. Pain sensations have been described in the clinical evaluation of lipedema, but its etiology remains poorly understood. We hypothesized…
Chakraborty A et al. · International journal of molecular sciences · 7 set 2022
Lipedema is a disorder characterized by an excessive accumulation of subcutaneous body fat, mainly bilateral and symmetrical accumulation of fat deposits, particularly in the lower extremities excluding feet. Pain (spontaneous or…
Jeziorek M et al. · Diabetes, metabolic syndrome and obesity : targets and therapy · 22 ago 2022
To contribute to a more in-depth assessment of shape, volume, and asymmetry of the lower extremities in patients with lipedema or lymphedema utilizing volume information from MR imaging. A deep learning (DL) pipeline was…
Lipoedema is a progressive adipose (fat) disorder, and little is known about its psychological effect. This study aimed to determine the experiences of physical and mental health and health care across stages of lipoedema.…
Clarke C et al. · Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 16 ago 2022
Lipoedema is a chronic feminine disease with disproportional painful fat deposition of the lower body half and occassional arm affection. The objective of the present study was to assess LA volumetric and functional properties by…
Nemes A et al. · Postepy dermatologii i alergologii · 14 jul 2022
Lipedema is an inflammatory subcutaneous adipose tissue disease that develops in women and may progress to lipolymphedema, a condition similar to lymphedema, in which lymphatic dysfunction results in irresolvable edema. Because…
Rasmussen JC et al. · Obesity (Silver Spring, Md.) · 15 jun 2022
(1) Background: Due to insufficient knowledge of lipoedema, the treatment of this disease is undoubtedly challenging. However, more and more researchers attempt to incorporate the most effective lipoedema treatment methods. When…
Czerwińska M, Teodorczyk J, Hansdorfer-Korzon R · International journal of environmental research and public health · 10 jun 2022
Background: Lipedema of lower limbs is characterized by bilateral accumulations of excess adipose tissue starting from the ankle to the hips and buttocks. The studies with lymphoscintigraphy (LSC) and magnetic resonance (MR)…
Zaleska MT, Olszewski WL, Krzesniak NE · Lymphatic research and biology · 8 jun 2022
Lipedema exhibits excessive lower-extremity subcutaneous adipose tissue (SAT) deposition, which is frequently misidentified as obesity until lymphedema presents. MR lymphangiography may have relevance to distinguish lipedema from…
Crescenzi R et al. · Journal of magnetic resonance imaging : JMRI · 3 jun 2022
Lipedema is characterized as an abnormal deposition of fat in the buttocks and legs bilaterally that may be accompanied by swelling, pain, and tenderness. It is still often confused with more frequent conditions such as obesity…
Amato ACM et al. · Jornal vascular brasileiro · 23 mai 2022
Lipedema is a chronic, progressive disease of adipose tissue with unknown etiology. Based on the relevance of the stromal vascular fraction (SVF) cell population in lipedema, we performed a thorough characterization of…
Lipedema patients suffer not only from visual stigma but also reduction in their quality of life through pain and performance loss in daily life. In clinical practice, it is still difficult to reliably diagnose the disease. This…
Hamatschek M et al. · Journal of clinical medicine · 17 mai 2022
Lipedema is an underdiagnosed condition in women, characterized by a symmetrical increase in subcutaneous adipose tissue (SAT) in the lower extremities, sparing the trunk. The lipedema SAT has been found to be resistant to diet,…
Sørlie V et al. · Obesity science & practice · 21 abr 2022
Lipedema is a multifaceted chronic fat disorder characterized by the bilateral and disproportionate accumulation of fat predominantly in the lower body regions of females. Research strongly supports that estrogen factors likely…
Hill JL et al. · Methods and protocols · 15 abr 2022
The lymphatic contribution to the circulation is of paramount importance in regulating fluid homeostasis, immune cell trafficking/activation and lipid metabolism. In comparison to the blood vasculature, the impact of the…
Rockson SG et al. · Clinical and translational medicine · 1 abr 2022
Despite an increasing demand for surgical treatment of lipedema, the evidence for liposuction is still limited. Little is known about the influence of disease stage, patient age, body mass index, or existing comorbidities on…
Kruppa P et al. · Plastic and reconstructive surgery · 1 mar 2022
Lipedema is a disabling disease characterized by symmetric enlargement of the lower and/or upper limbs due to deposits of subcutaneous fat, that is easily misdiagnosed. Lipedema can be primary or syndromic, and can be the main…
Michelini S et al. · Journal of personalized medicine · 11 fev 2022
Lymphedema is characterized by swelling and fibroadipose tissue deposition that is a physically, psychologically, and socially debilitating condition due to chronic and progressive nature of the disease. Treatment benefit…
Duygu Yildiz E, Bakar Y, Keser I · Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing · 26 jan 2022
Lipedema often remains undiagnosed in patients with obesity, leading to mismanagement of treatment. Because of this, despite remarkable weight loss after bariatric surgery and decreases in hip and abdomen circumference, some…
Cornely ME et al. · Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 7 jan 2022
Lower extremity edema is a common complaint of patients across all medical specialties. This is a wide group of conditions, ranging from relatively minor conditions such as false swelling in lipedema to life-threatening…
Lipedema is a chronic and progressive disease associated with lymphatic impairment at later stages. The aim of our study was to describe the functional status and anatomy of lower limb superficial lymphatic system using…
Buso G et al. · Microvascular research · 9 dez 2021
Lipedema, a poorly understood chronic disease of adipose hyper-deposition, is often mistaken for obesity and causes significant impairment to mobility and quality-of-life. To identify molecular mechanisms underpinning lipedema,…
Ishaq M et al. · International journal of obesity (2005) · 11 nov 2021
Background: Lipedema is a distinct adipose disorder from obesity necessitating awareness as well as different management approaches to address pain and optimize quality of life (QoL). The purpose of this proof-of-principle study…
Donahue PMC et al. · Lymphatic research and biology · 8 nov 2021
(1) Background: Lipoedema is a disease characterized by excessive bilateral and symmetrical accumulation of subcutaneous tissue in the lower extremities. It is a poorly understood condition, and low awareness of its existence…
Czerwińska M, Ostrowska P, Hansdorfer-Korzon R · International journal of environmental research and public health · 28 set 2021
To examine the common and specific characteristics of fibromyalgia and lipedema, two chronic soft-tissue pain syndromes without curative therapy options. Diseases' characteristics were compared using the findings of extensive…
Angst F et al. · Journal of pain research · 17 set 2021
The association between serum Vitamin D (Vit. D) and mood disorders in lipedema patients has not been investigated. Therefore, the main aim of this study is to investigate the correlation between serum Vit. D, depression and…
Al-Wardat M et al. · Hormone molecular biology and clinical investigation · 29 jul 2021
Lipedema is a chronic, progressive disease that almost exclusively affects women and often misdiagnosed as obesity or primary lymphedema. Research concerning lipedema is sparse, and there is a lack of studies focusing on women's…
Melander C, Juuso P, Olsson M · Health care for women international · 12 jul 2021
Lipedema is a loose connective tissue disease predominantly in women identified by increased nodular and fibrotic adipose tissue on the buttocks, hips and limbs that develops at times of hormone, weight and shape change including…
This study examined the disease-specific quality of life (QoL) in lipoedema patients undergoing treatment for the condition with liposuction. We conducted a retrospective analysis of all patients (n = 69) who underwent…
Schlosshauer T et al. · International wound journal · 5 mai 2021
Lipedema is a loose connective tissue disease affecting the limbs of women, that is difficult to lose by diet, exercise, or bariatric surgery. Publications from Europe demonstrate that lipedema reduction surgery improves quality…
Herbst KL et al. · Plastic and reconstructive surgery. Global open · 23 abr 2021
Lipedema is characterized by the deposition of abnormal fat in the lower and upper limbs bilaterally. It is a disease with high prevalence and genetic characteristics. Non-specific and non-quantified increases in the thickness of…
Objective: The aim of this study is to investigate the effect of complex decongestive physiotherapy (CDP) plus intermittent pneumatic compression (IPC) applications on upper extremity circumference and volume in patients with…
Volkan-Yazici M, Esmer M · Lymphatic research and biology · 5 abr 2021
Lipedema is an infrequently recognized disorder. It is characterized by bilateral painful enlargement of the legs due to abnormal depositions of subcutaneous fat, that can result in considerable disability. The diagnosis is…
Naef V, Alvarez Martinez D, Cortes B · Revue medicale suisse · 31 mar 2021
Lipedema is an adipose tissue disorder characterized by the disproportionate increase of subcutaneous fat tissue in the lower and/or upper extremities. The underlying pathomechanism remains unclear and no molecular biomarkers to…
Wolf S et al. · International journal of molecular sciences · 24 mar 2021
Lipedema is a chronic, progressive disease that occurs almost exclusively in women and leads to pathological, painful fat growths at the extremities. Only symptomatic therapy can be offered since the etiology of the disease has…
Sandhofer M et al. · Journal of drugs in dermatology : JDD · 1 mar 2021
Background: Lymphatic disease patients make up a significant proportion of the US and world populations. Due to inadequate medical school training and underestimation of the impact of lymphatic circulation, lymphatic disease…
Chang D et al. · Lymphatic research and biology · 5 fev 2021
Lipoedema is a subcutaneous adipose tissue disease characterized by the increase in the amount and structure of fat mass (FM) in specific areas, causing pain and discomfort. 95% of patients fail to lose weight in the lipoedema…
Lipedema is a chronic and progressive disease. Most studies agree that it is underdiagnosed and undertreated. The aim of this study was to identify the diagnostic characteristics and types of treatment for lipedema in the Spanish…
Vaquero Ramiro E et al. · Rehabilitacion · 15 jan 2021
Lipedema is a type of subcutaneous adipose tissue disorder that affects mainly women. Its main symptom is bilateral fat accumulation on the extremities with associated pain in the affected areas. Despite growing interest in…
Dudek JE, Białaszek W, Gabriel M · BMC women's health · 15 jan 2021
Primary lymphedema is a rare chronic pathology associated with constitutional abnormalities of the lymphatic system. The objective of this French National Diagnosis and Care Protocol (Protocole National de Diagnostic et de Soins;…
Vignes S et al. · Orphanet journal of rare diseases · 6 jan 2021
Lipedema is a chronic disease seen frequently in women that causes abnormal fat deposition in the lower limbs and associated bruising and pain. Despite increasing knowledge concerning lipedema, there are still aspects of…
Both lipedema and juxta-articular adiposis dolorsa are painful disorders of subcutaneous adipose tissue. We investigated 297 female patients with lipedema treated at our department for the presence of juxta-articular adiposis…
Lipedema is greatly underdiagnosed and there is a lack of low-cost tools to facilitate diagnostic. We created a lipedema screening questionnaire based on a questionnaire for assessing symptoms. The study objectives were to…
Amato ACM et al. · Jornal vascular brasileiro · 11 dez 2020
Lipedema is a widespread in concern of etiology partially unknown disease especially in women. In many cases it is accompanied by bleeding complications. Our current work focuses on possible coagulation disorders as potential…
The aim of the present study was to evaluate the prevalence of subclinical and clinical systemic lymphedema in patients with lipedema and different body mass index (BMI) values. A cross-sectional study was conducted to determine…
Lipedema (LI) is a common yet misdiagnosed condition, often misconstrued with obesity. LI affects women almost exclusively, and its painful and life-changing symptoms have long been thought to be resistant to the lifestyle…
Multiple associated comorbidities have been described for lipedema patients. Disease diagnosis still remains challenging in many cases and is frequently delayed. The purpose of this study was to determine the most common…
Ghods M et al. · Dermatologic therapy · 22 nov 2020
In recent years, crowdfunding for medical expenses has gained popularity, especially in countries without universal health coverage. Nevertheless, universal coverage does not imply covering all medical costs for everyone. In…
The growth and differentiation of adipose tissue-derived stem cells (ASCs) is stimulated and regulated by the adipose tissue (AT) microenvironment. In lipedema, both inflammation and hypoxia influence the expansion and…
Al-Ghadban S et al. · International journal of molecular sciences · 7 nov 2020
Background: The aim of this study is to investigate the effect of complex decongestive physiotherapy (CDP) plus intermittent pneumatic compression (IPC) applications on lower extremity limb circumference and volume in patients…
Volkan-Yazıcı M, Yazici G, Esmer M · Lymphatic research and biology · 30 out 2020
Lipoedema is characterized as subcutaneous lipohypertrophy in association with soft-tissue pain affecting female patients. Recently, the disease has undergone a paradigm shift departing from historic reiterations of defining…
Background: Fluid in lymphedema tissue appears histologically as spaces around vessels and between dermal skin fibers. Lipedema is a painful disease of excess loose connective tissue (fat) in limbs, almost exclusively of women,…
Allen M, Schwartz M, Herbst KL · Women's health reports (New Rochelle, N.Y.) · 14 out 2020
Compression hosiery is commonly used for the management of lymphoedema as well as lipoedema, but it is more commonly indicated for the lower limbs than for the upper limbs. The effects of compression hosiery on upper-limb…
Elwell R, Rich A · British journal of community nursing · 1 out 2020
BACKGROUND/OBJECTIVES: Patients with obesity and lipedema commonly are misdiagnosed as having lymphedema. The conditions share phenotypic overlap and can influence each other. The purpose of this study was to delineate…
Greene AK, Sudduth CL · International journal of obesity (2005) · 15 set 2020
Lipedema is characterized as abnormal bilateral deposition of fat in the buttocks and legs that may be accompanied by orthostatic edema in women. A questionnaire for assessment of lipedema symptoms has previously been published…
Amato ACM et al. · Jornal vascular brasileiro · 31 ago 2020
Lipedema is an often underdiagnosed chronic disorder that affects subcutaneous adipose tissue almost exclusively in women, which leads to disproportionate fat accumulation in the lower and upper body extremities. Common…
Michelini S et al. · International journal of molecular sciences · 29 ago 2020
Long-term results following liposuction in patients with lipedema were available only for an average period of 8 years. To find out whether the improvements persist for a further 4 years. In 60 patients with lipedema a…
Liposuction is one of the most common procedures undertaken in plastic surgery with a steadily increasing trend over the years. Although usually performed as an aesthetic procedure for body contouring, it can also be utilized in…
Georgiou I et al. · Aesthetic plastic surgery · 12 ago 2020
Literature on the validity of outcome measurement in lymphedema and lipedema is very sparse. This study aimed to examine the convergent, divergent and discriminant validity of a set of 5 instruments in both conditions.…
Angst F et al. · Health and quality of life outcomes · 22 jul 2020
Genetic or acquired defects of the lymphatic vasculature often result in disfiguring, disabling, and, occasionally, life-threatening clinical consequences. Advanced forms of lymphedema are readily diagnosed clinically, but more…
Lipedema is a chronic adipose tissue disorder characterized by the disproportional subcutaneous deposition of fat and is commonly misdiagnosed as lymphedema or obesity. The molecular determinants of the lipedema remain largely…
Felmerer G et al. · Scientific reports · 2 jul 2020
Lipedema is characterized by pain, fatigue, and excessive adipose tissue and sodium accumulation of the lower extremities. This case-control study aims to determine whether sodium or vascular dysfunction is present in the central…
Lipedema is a chronic and progressive disease characterized by a symmetrical and bilateral swelling of the lower extremities. In general, the feet are not involved. Lipedema is believed to affect nearly 1 in 9 adult women…
Tartaglione G et al. · World journal of nuclear medicine · 27 jun 2020
Lipedema is a lymphedema-masquerading symmetrical, bilateral and disproportional obesity. Its conservative maintenance treatment comprises the use of flat-knitted compression pantyhoses. Lipedema is known to be associated with…
To assess imaging findings and characteristics of the lymphatic system in patients affected by lipedema and lipolymphedema of the lower extremities on Non-Contrast MR Lymphography (NCMRL). 44 lower extremities in 11 consecutive…
Cellina M et al. · Magnetic resonance imaging · 17 jun 2020
The aim was to quantify and to compare the associations between longitudinal changes in pain and depression in different chronic pain conditions. Data were retrieved from 6 observational cohort studies. From baseline to the…
Angst F et al. · Journal of affective disorders · 19 mai 2020
Lipedema is a common adipose tissue disorder affecting women, characterized by a symmetric subcutaneous adipose tissue deposition, particularly of the lower extremities. Lipedema is usually underdiagnosed, thus remaining an…
Felmerer G et al. · The Journal of surgical research · 11 mai 2020
Lipedema is a chronic, common but underdiagnosed disease masquerading obesity, with female predominance, characterized by disproportional abnormal adipose tissue distribution of the lower and also upper extremities. The present…
Nemes A et al. · Journal of clinical ultrasound : JCU · 11 mai 2020
Lipedema is a chronic, progressive disease of adipose tissue with lack of consistent diagnostic criteria. The aim of this study was a thorough comparative characterization of extracellular microRNAs (miRNAs) from the stromal…
Priglinger E et al. · Scientific reports · 29 abr 2020
Selenium is a trace element, which is utilized by the human body in selenoproteins. Their main function is to reduce oxidative stress, which plays an important role in lymphedema and lipedema. In addition, selenium deficiency is…
Pfister C, Dawczynski H, Schingale F · Nutrients · 25 abr 2020
The aim of this study is to compare tissue sodium and fat content in the upper and lower extremities of participants with lipedema versus controls using magnetic resonance imaging (MRI). MRI was performed at 3.0 T in females with…
Crescenzi R et al. · Obesity (Silver Spring, Md.) · 9 abr 2020
Lipoedema is an incurable chronic disease causing limb deformity, painful skin and excessive ecchymosis. Compression garments are frequently recommended to manage symptoms, but the existing products are not designed specifically…
Paling I, Macintyre L · British journal of community nursing · 1 abr 2020
Lipoedema, an adipose tissue disorder, is a poorly visible, often unrecognised condition. To foster a greater understanding of the significant and debilitating impacts faced by women living with lipoedema, the charity Lipoedema…
Fetzer A · British journal of community nursing · 1 abr 2020
Chronic oedema is a term that encompasses several causes that lead to oedema formation in any part of the body. This includes lymphoedema and its subcategories. Despite the assumption that these are different, there are more…
Cooper-Stanton G · British journal of community nursing · 1 abr 2020
Lipedema is a condition of painful increase in subcutaneous fat affecting almost exclusively women. Several studies have examined the effectiveness of liposuction in the treatment of lipedema, but none has focused on…
Witte T et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 14 mar 2020
Lipedema is a disorder of adipose tissue characterized by abnormal subcutaneous fat deposition, leading to swelling and enlargement of the lower limbs and trunk. The aim of this study was to evaluate the lipedema phenotype by…
Di Renzo L et al. · European review for medical and pharmacological sciences · 1 mar 2020
Lipedema is a painful loose connective tissue disorder characterized by a bilaterally symmetrical fat deposition in the lower extremities. The goal of this study was to characterize the adipose-derived stem cells (ASCs) of…
Lipedema is a chronic, progressive disorder of subcutaneous adipose tissue that usually affects the lower extremities of women. Also known as "two-body syndrome," the fat accumulations in lipedema are unsightly and painful. The…
Sandhofer M et al. · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 1 fev 2020
Lower extremity lymphedema is frequently encountered in the vascular clinic. Established dogma purports that cancer is the most common cause of lower extremity lymphedema in Western countries, whereas chronic venous insufficiency…
Dean SM et al. · Journal of vascular surgery. Venous and lymphatic disorders · 25 jan 2020
Lipedema is a fat disorder that is often misdiagnosed. It was first identified at the Mayo Clinic in 1940, but medical schools do not include it in their curriculum and is therefore poorly understood. It presents as…
Caruana M · Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses · 1 jan 2020
Although a large number of adult women worldwide are affected by lipedema, the physiologic conditions triggering onset and progression of this chronic disease remain enigmatic. In the present study, a descriptive epidemiologic…
Bauer A et al. · Plastic and reconstructive surgery · 1 dez 2019
Lymphatic insufficiency might play a significant role in the pathophysiology of lipoedema. Liposuction is up to now the best treatment. As liposuction is invasive, the technique could destruct parts of the lymphatic system and by…
Although lipedema is often clinically distinguished from lymphedema, there is considerable overlap between the two entities. The purpose of this study was to evaluate lymphoscintigraphic findings in patients with lipedema to…
Gould DJ et al. · Journal of reconstructive microsurgery · 23 set 2019
Lipedema is characterized by localized accumulation of fat in the extremities, which is typically unresponsive to dietary regimens or physical activity. Although the disease is well described and has a high incidence, little is…
Bauer A et al. · Plastic and reconstructive surgery · 1 set 2019
640 patients from a specialist clinic for operative lymphology were surveyed with the help by a questionnaire issued by the German Society of Pain Therapy (Deutsche Schmerzgesellschaft e. V.). This survey collected responses to…
Gensior MHL, Cornely M · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 14 ago 2019
Three-dimensional surface imaging (3DSI) has proven to be useful in providing objective aid to the planning process and documentation of various plastic-surgical procedures. Although this technology is routinely used in the…
Etzel L et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 14 ago 2019
Background: Lipedema and Dercum's disease (DD) are incompletely characterized adipose tissue diseases, and objective measures of disease profiles are needed to aid in differential diagnosis. We hypothesized that fluid properties,…
Crescenzi R et al. · Lymphatic research and biology · 13 ago 2019
Lipedema is a barely recognized and poorly diagnosed, but common disease affecting almost exclusively female patients. The pathomechanism of lipedema is not known, and clinically, it is a bilateral, symmetrical, disproportional…
Nemes A et al. · Echocardiography (Mount Kisco, N.Y.) · 18 jul 2019
Adipose tissue insulin resistance has been observed in obese subjects and is considered an early metabolic defect that precedes insulin resistance in muscle and liver. Although Asians can readily develop metabolic disease without…
Sugimoto D et al. · The Journal of clinical endocrinology and metabolism · 1 jun 2019
Background: The aim of this study was to investigate the Turkish adaptation, validity, and reliability of the Patient Benefit Index-Lymphedema (PBI-L) ensuring direct assessment of the benefit in patients with lymphedema (LE),…
Duygu E, Bakar Y, Keser I · Lymphatic research and biology · 30 mai 2019
Lipoedema used to be a rather unknown disease. In the past five years, it has gained increasing awareness, especially through media attention. Besides non-surgical treatment by complex conservative decongestion, there are an…
Motamedi M, Herold C, Allert S · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 16 abr 2019
In case of an acute leg swelling a deep leg vein thrombosis needs to be excluded. In order to do this, compression sonography and the D-dimer-test are applied in the framework of an established diagnostic algorithm. The ensuing…
Präve F, Hoffmann K · Deutsche medizinische Wochenschrift (1946) · 14 mar 2019
Lipedema is a common painful SAT disorder characterized by enlargement of fat primarily in the legs of women. Case reports of lipedema tissue samples demonstrate fluid and fibrosis in the interstitial matrix, increased…
Al-Ghadban S et al. · Journal of obesity · 3 mar 2019
Lipedema is a painful disease of subcutaneous adipose tissue leading to bilateral increase of leg and/or arm volume, but sparing hands and feet. Although conservative treatment with complex decongestive therapy has been…
Wollina U, Heinig B · Dermatologic therapy · 30 jan 2019
Tape measures continue to be used for the diagnosis and evaluation of lipoedema and lymphoedema in the clinical routine. Extremity volumes are calculated based on standardised circumferential measurements. Other volume…
Koban KC et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 8 jan 2019
Lipoedema is a progressive disease, which predominantly affects women. It is characterised by circumferential growth, with increase in fat tissue of the extremities, and can lead to oedema. In contrast, the lymphoedema is defined…
Zetzmann K et al. · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 8 jan 2019
Lipoedema is a painful, chronic progressive disorder of adipose tissue, characterised by symmetrical swelling of the lower and/or upper limbs. Due to a lack of awareness, lipoedema is frequently misdiagnosed. However, accurate…
Wiedner M, Aghajanzadeh D, Richter DF · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 8 jan 2019
Background: Sonographic findings differ in patients with primary lipedema from those with lymphedema. This project was designed to quantify those differences and objectively characterize findings of lipedema and lymphedema in the…
Iker E et al. · Lymphatic research and biology · 7 jan 2019
Advanced lymphedema is associated with a number of adverse skin changes including color, thickening of the epidermis, dryness, and hyperkeratosis. These changes are related to prolonged lymph stasis and contribute to an increased…
Chronic lymphoedema (CLE) is a burdensome disease of multiple causes leading to significant reductions in health-related quality of life (HRQoL). A specific method to assess HRQoL is the Freiburg Life Quality Assessment for…
Augustin M et al. · The British journal of dermatology · 5 out 2018
Lipoedema is painful nodular subcutaneous adipose tissue (SAT) on legs and arms of women sparing the trunk. People with Dercum disease (DD) have painful SAT masses. Lipoedema and DD fat resists loss by diet and exercise.…
We assessed body composition, bone mineral density (BMD), glucose and lipids in Williams syndrome (WS), a rare microdeletion disorder. Individuals with WS had outpatient assessment at Massachusetts General Hospital. Controls were…
Shaikh S et al. · Clinical endocrinology · 18 set 2018
Lipedema is a syndrome that is characterised by edema, an accumulation of fat, pain and haematomas in the lower limbs that principally affects women. Diagnosis is currently based on clinical criteria, since there is no accurate…
Forner-Cordero I et al. · Revista espanola de medicina nuclear e imagen molecular · 28 ago 2018
Implementation of guideline recommendations for the diagnosis and therapy of lipedema and lymphedema seems to be problematic in daily routine. Systematic data for Germany are missing. The aim of the study was data collection…
Reich-Schupke S, Mohren E, Stücker M · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 jun 2018
Lipoedema is a chronic disorder in which excessive fat distribution occurs predominantly from the waist down, resulting in a disproportion between the lower extremities and upper torso. Lipoedema is often not recognized, while…
Romeijn JRM et al. · Dermatology and therapy · 10 mai 2018
Lipedema is a chronic, progressive adipose tissue disorder that may impact the quality of life of women who suffer from it. The main aim of this study was to asses the role of perceived symptom severity, physical and…
Dudek JE et al. · Psychology, health & medicine · 3 abr 2018
Lipedema is a fat disorder that is often misdiagnosed. It was first identified at the Mayo Clinic in 1940, but medical schools do not include it in their curriculum and is therefore poorly understood. It presents as…
Caruana M · Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses · 1 jan 2018
The present study aimed to assess LV rotational mechanics by three-dimensional speckle-tracking echocardiography (3DSTE) in lipedema (n=25), lymphedema (n=26) patient groups with age- and gender-matched healthy controls (n=54). 3…
To test the hypothesis that tissue sodium and adipose content are elevated in patients with lipedema; if confirmed, this could establish precedence for tissue sodium and adipose content representing a discriminatory biomarker for…
Crescenzi R et al. · Obesity (Silver Spring, Md.) · 27 dez 2017
Lymphoedema results from a failure of the lymphatic system. The consequences are swelling, skin and tissue changes and predisposition to infection. Lipoedema, however, results from the predisposition of an excessive number of fat…
Elwell R, Heal D, Lister L · British journal of community nursing · 1 out 2017
Lipedema is a condition consisting of painful bilateral increases in subcutaneous fat and interstitial fluid in the limbs with secondary lymphedema and fibrosis during later stages. Combined decongestive therapy (CDT) is the…
Dadras M et al. · Archives of plastic surgery · 15 jul 2017
The use of velcro compression wrapping devices in the management of lymphoedema and chronic oedema is not a new concept. Wraps have been available for many years and are being used widely in clinic and community settings where…
Lee N, Lawrence S · British journal of community nursing · 1 mai 2017
An audit of 100 new patients attending a specialist lymphoedema clinic revealed 52% presented with chronic oedema. More than half (58%) of the chronic oedema group presented with skin changes whereas 14% of those with lipoedema,…
Todd M et al. · British journal of community nursing · 1 mai 2017
Lymphedema is a complex and burdensome medical problem and requires continuous specific therapy. The aim of this cross-sectional study of community lymphedema care in the metropolitan area of Hamburg, Germany, was to evaluate…
Herberger K et al. · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 27 abr 2017
Lipedema is a hormone-related disease of women characterized by enlargement of the extremities caused by subcutaneous deposition of adipose tissue. In healthy patients application of autologous adipose tissue-derived cells has…
Lipedema is a disproportional obesity featuring spontaneous or light pressure-induce pain and frequent hematoma formation due to even minor traumatic injuries. It is generally distinguished from general obesity primarily based on…
People with lipedema or Dercum's disease (DD) can have a similar distribution of excess painful nodular subcutaneous adipose tissue (SAT), making them difficult to differentiate. Case series of 94 patients with DD, 160 with…
Beltran K, Herbst KL · International journal of obesity (2005) · 18 nov 2016
Lipoedema is a chronic progressive adipose disorder that affects mainly women and presents as symmetrical enlargement of the buttocks and legs. It is commonly misdiagnosed as obesity or lymphoedema, but careful assessment will…
Todd M · British journal of community nursing · 1 out 2016
Lipedema, or adiposis dolorosa, is a common adipose tissue disorder that is believed to affect nearly 11% of adult women worldwide. It is characterized most commonly by disproportionate adipocyte hypertrophy of the lower…
Buck DW, Herbst KL · Plastic and reconstructive surgery. Global open · 28 set 2016
This study aimed to explore patients' perceptions regarding the impact that lower limb chronic oedema has on their quality of life (QoL). A quantitative descriptive design was used to collect data from patients with lower limb…
Greene A, Meskell P · International wound journal · 4 ago 2016
While there is no proven cure for lipoedema, early detection is key as specialist treatments, complemented by self-management techniques, can improve symptoms and prevent progression. There is no universal approach as the correct…
Fetzer A · British journal of community nursing · 1 abr 2016
Selecting the most appropriate compression garments is vital in the long-term management of venous disease and chronic oedema. The range of styles has improved greatly over the years and many garments are available on the UK Drug…
Todd M, Elwell R, Pritchard E · British journal of community nursing · 1 abr 2016
Lipedema is a chronic disorder characterized by abnormal distribution of subcutaneous adipose tissue on the proximal extremities, pain and capillary fragility. Its etiology is unknown but in analogy to central obesity, chronic…
Schneble N, Wetzker R, Wollina U · Journal of biological regulators and homeostatic agents · 1 jan 2016
Long-term results following liposuction in patients with lipoedema are available only for an average period of 4 years. To find out whether the improvement of complaints persists for a further 4 years. In a single-centre study,…
Baumgartner A, Hueppe M, Schmeller W · The British journal of dermatology · 26 dez 2015
Vascular anomalies and related conditions cause overgrowth of tissues. The purpose of this study was to determine the efficacy and safety of liposuction techniques for pediatric overgrowth diseases. Patients treated between 2007…
Couto JA, Maclellan RA, Greene AK · Plastic and reconstructive surgery · 1 out 2015
Lipedema is a poorly understood clinical entity that is frequently under-diagnosed and neglected or else confused with lymphoedema. However, in most cases, diagnosis is simple and does not usually necessitate laboratory…
Truchetet F, Bonhomme A · Annales de dermatologie et de venereologie · 6 ago 2015
Lipoedema is a chronic, progressive adipose disorder of unknown etiology, often underdiagnosed or misdiagnosed as obesity. It manifests itself with accumulation of the fat in lower parts of the body and associated edema and, due…
Dudek JE, Białaszek W, Ostaszewski P · Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 28 jul 2015
Women wait decades for an accurate diagnosis of lipoedema. Earlier diagnosis is essential to prevent the condition progressing to lymphoedema, with its risk of life-threatening cellulitis.
Mason M · Nursing standard (Royal College of Nursing (Great Britain) : 1987) · 8 jul 2015
Liposuction for lymphoedematous limbs is an effective treatment for chronic lymphoedema, with excellent long-term results in well-selected patients. In 2008 NICE produced guidelines 'Liposuction for Chronic lymphoedema',…
Teo I, Munnoch DA · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 29 mai 2015
Frequently misdiagnosed as obesity, lipoedema is chronic condition involving an abnormal build-up of fat cells in the legs, thighs and buttocks that cannot be shifted by exercise or dieting. Estimated to affect up to 11% of the…
Fetzer A, Fetzer S · British journal of community nursing · 1 abr 2015
Microcannular liposuction in tumescent anesthesia is the most effective treatment for painful lipedema. Tumescent anesthesia is an established and safe procedure in local analgesia when performed according to guidelines. Major…
Wollina U, Graf A, Hanisch V · Wiener medizinische Wochenschrift (1946) · 21 jan 2015
Application of microcurrents of bioresonance may allow protein aggregates lysis and a related enhancement of lymphatic drainage. Combining bioresonance with transcutaneous passage of active principles, by means of skin…
Elio C et al. · Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia · 1 dez 2014
Compression therapy is the mainstay of treatment in the management of lymphoedema and lipoedema. However, due to variance in the location, severity and type of the condition, patients often have to compromise on garments to…
Wigg J, Lee N · British journal of community nursing · 1 out 2014
Elephantiasis nostras is a rare complication in advanced lipo-lymphedema. While lipedema can be treated by liposuction and lymphedema by decongestive lymphatic therapy, elephantiasis nostras may need debulking surgery. We present…
Lipedema is a rare female disorder with a characteristic distribution of adipose tissue hypertrophy on the extremities, with pain and bruising. In advanced stages, reduction of adipose tissue is the only available effective…
Wollina U, Heinig B, Nowak A · Clinical, cosmetic and investigational dermatology · 23 jan 2014
Distinguishing lymphoedema from lipoedema in women with swollen legs can be difficult. Local tissue water content can be quantified using tissue dielectric constant (TDC) measurements. To examine whether TDC measurements can…
Birkballe S et al. · The British journal of dermatology · 1 jan 2014
The management of lymphoedema is complex and should be based on guidelines. To date, no data assessing quality of care in lymphoedema in Germany are available. We aimed at evaluating the quality of care of lymphoedema in the…
Herberger K et al. · Dermatology (Basel, Switzerland) · 2 jul 2013
Lipoedema UK was founded in 2012 by women with lipoedema and clinicians working in the Lymphoedema Service at St George's Hospital in London. Its patron is Professor Peter Mortimer, the UK's leading Lipoedema expert, and its…
Evans S · British journal of community nursing · 1 abr 2013
Functional pelvic disorders in patients undergoing conservative surgical approach for rectal cancer are considered a major public health issue and represent one third of cost of colorectal cancer. We investigated the hypothesis…
Vannelli A et al. · European review for medical and pharmacological sciences · 1 abr 2013
Liposuction is the most frequent aesthetic procedure worldwide for adipose tissue reduction and treatment of lipedema. It is being employed with increasing frequency. In 2010, in the USA more than 200.000 liposuctions were…
Sattler G, Eichner S · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 mar 2013
Lipedema is a disproportionate, symmetrical fatty swelling characterized by pain and bruising existing almost exclusively among women. We undertook a systematic review of the available literature about lipedema, given the lack of…
Forner-Cordero I et al. · Clinical obesity · 3 ago 2012
Lipedema is a disproportional obesity due to unknown pathomechanism. Its major hallmark is frequent hematoma formation related to increased capillary fragility and reduced venoarterial reflex. Beyond microangiopathy, both venous…
Lipedema is a chronic disease of lipid metabolism that results in the symmetrical impairment of fatty tissue distribution and storage combined with the hyperplasia of individual fat cells. Lipedema occurs almost exclusively in…
Shin BW et al. · Annals of rehabilitation medicine · 30 dez 2011
Lipedema is a disproportional obesity featuring light pressure-induced or spontaneous pain. On the basis of our clinical observations, lymphedema therapy, as practiced in our clinic, reduces the perception of pain beyond leg…
Lipoedema is a painful disease in women with circumscribed increased subcutaneous fatty tissue, oedema, pain and bruising. Whereas conservative methods with combined decongestive therapy (manual lymphatic drainage, compression…
Schmeller W, Hueppe M, Meier-Vollrath I · The British journal of dermatology · 17 nov 2011
Unclear extremity complaints are common symptoms of inpatients. In a subset of these patients, a clinical suspicion of deep vein thrombosis (DVT) results; this needs to be quickly and definitively clarified by a vascular…
Taute B, Melnyk H, Podhaisky H · Medizinische Klinik (Munich, Germany : 1983) · 28 set 2010
Lipedema is a painful, genetically induced abnormal deposition of subcutaneous fat in the extremities of almost exclusively women. The pathogenesis is unknown and no curative treatment is available. Conservative therapy…
Rapprich S, Dingler A, Podda M · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 7 set 2010
Adiposis dolorosa (AD) is a rare disorder of painful nodular subcutaneous fat accompanied by fatigue, difficulty with weight loss, inflammation, increased fluid in adipose tissue (lipedema and lymphedema), and hyperalgesia.…
Herbst KL, Rutledge T · Journal of pain research · 20 ago 2010
Lipoedema is an accumulation of fat abnormally distributed in the lower limbs, and lymphoedema is oedema caused by a deficiency of the lymphatic system. High-resolution ultrasound operating at 20 MHz makes it possible to…
Naouri M et al. · The British journal of dermatology · 16 abr 2010
Lipoedema is a distinct clinical condition characterized by bilateral, symmetrical enlargement of the buttocks and lower limbs owing to excess deposition of subcutaneous fat. It is found almost exclusively in women. The common…
Todd M · British journal of community nursing · 1 abr 2010
We evaluated the outcome and risks of tumescence liposuction in patients with advanced lipedema or Dercum's disease. Six patients treated at a single center during the years 2004 to 2008 have been included. All patients were…
Wollina U, Goldman A, Heinig B · Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia · 1 abr 2010
Lipedema is a condition characterized by swelling and enlargement of the lower limbs due to abnormal deposition of subcutaneous fat. Lipedema is an under-recognized condition, often misdiagnosed as lymphedema or dismissed as…
Child AH et al. · American journal of medical genetics. Part A · 1 abr 2010
A 23-year-old male was referred to our clinic with diagnosis of idiopathic isolated growth hormone deficiency. A detailed family history revealed short stature and swelling of legs which only affected females in four generations…
Bano G et al. · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 16 jul 2009
To assess for the first time the morphology of the lymphatic system in patients with lipedema and lipo-lymphedema of the lower extremities by MR lymphangiography. 26 lower extremities in 13 consecutive patients (5 lipedema, 8…
Lohrmann C, Foeldi E, Langer M · Microvascular research · 27 jan 2009
Lipedema is a disproportional obesity featuring frequent hematoma formation due to even minor traumatic injuries. On the basis of clinical observations, complete decongestive physiotherapy diminishes the incidence of hematomas…
Lipoedema is a fat distribution disorder causing massive, bilaterally symmetrical enlargement of the lower and in some cases the upper extremities in women. The atraumatic, anatomically appropriate procedure of water jet-assisted…
Stutz JJ, Krahl D · Aesthetic plastic surgery · 29 jul 2008
The population of morbidly obese patients, along with the incidence of lymphedema and massive localized lymphedema associated with this condition, is increasing. A 5-year retrospective review of data (2000-2005) shows that the…
Fife CE, Carter MJ · Ostomy/wound management · 1 jan 2008
This paper provides the results of examination of 413 patients aged 15 to 79 years (mean age 43.2 years) with different stages of CVI seen from 1995 to 2005. A complex of methods was employed: the clinical nmltimodality…
Tsukanov IT, Tsukanov AI · Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery · 1 jan 2007
Only a limited number of studies on cellulite have been published in the international literature and many of them reach somewhat antithetical conclusions. Consequently, it is not yet possible to reconcile the extreme differences…
Terranova F, Berardesca E, Maibach H · International journal of cosmetic science · 1 jun 2006
Lipedema is a rare and painful disease in women. Until recently, it could be treated only by conservative methods (combined physical therapy). To determine the efficacy and safety of surgery (liposuction) concerning appearance…
Schmeller W, Meier-Vollrath I · Journal of cutaneous medicine and surgery · 1 jan 2006
Many investigations and treatments exist for lower limb lymphoedema. We undertook a survey on the management of this condition by vascular surgeons and the resources available for its treatment in the UK. A questionnaire was…
Tiwari A, Myint F, Hamilton G · European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 1 dez 2005
In vivo measurements in 26 female patients with lipedema and cellulite parameters were carried out before and after therapy by means of complex physical decongestive therapy (CPDT) including manual lymph drainage and compression…
Siems W et al. · BioFactors (Oxford, England) · 1 jan 2005
Lipedema is characterized by bilateral enlargement of the legs due to abnormal deposition of fat tissue from pelvis to ankles. It is seen most frequently in obese women. Lipedema appears to be a distinct clinical entity but may…
Boursier V, Pecking A, Vignes S · Journal des maladies vasculaires · 1 dez 2004
Both generalized and localized edema needs to be submitted to a differential diagnostic investigation. In the case of edema affecting the lower extremities, in particular the Stemmer sign which is the inability to tent the skin…
Fries R · MMW Fortschritte der Medizin · 15 abr 2004
To evaluate the accuracy of computed tomography (CT) scan imaging in distinguishing lymphedema from deep venous thrombosis (DVT) and lipodystrophy (lipedema) in patients with swollen legs. CT scans of the lower limbs were…
"Lipedema," a special form of obesity syndrome, represents swelling of the legs due to an increase of subcutaneous adipose tissue. In 12 patients with lipedema of the legs and in 12 healthy subjects (controls), fluorescence…
The role of operative management of "symptomatic" varicose veins in patients with lower extremity lymphedema or lipedema is controversial. We reviewed the clinical outcome of 261 patients between 1989-1997 at the Földiclinic with…
The anatomical and functional status of the epifascial and subfascial lymphatic compartments was analyzed using two compartment lymphoscintigraphy in five groups of patients (total 55) with various forms of edema of the lower…
Two-compartment lymphoscintigraphy was developed to examine the sub- and epifascial lymphatics of the leg. Digital images were evaluated visually and semiquantitatively by calculating the uptake of activity within the lymph…
Bräutigam P et al. · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 ago 1997
Twenty-four healthy subjects and 16 patients with lymphedema and lipedema were studied with MRI and ultratomography. In chronic lymphedema, ultrasonography revealed a statistically significant increase of the subcutaneous fat…
Dimakakos PB et al. · International surgery · 1 jan 1997
Early terms of lymphostasis in lipedema can be detected with lymphoscintigraphy. A normal examination almost certainly excludes a lymphatic component. Indirect lymphography is only used to rule out morphological abnormalities of…
Weissleder H et al. · Zeitschrift fur Lymphologie. Journal of lymphology · 1 dez 1995
Lipedema is a chronic vascular disease almost exclusively of female sex, characterized by the deposit of fat on the legs, with an "Egyptian column" shape, orthostatic edema, hypothermia of the skin, alteration of the plantar…
In a review of 250 cases of lymphedema of the lower extremity, 9 patients were noted to share unique similarities in their history and physical findings. Although these patients had mild swelling in their pretibial areas and were…
Rudkin GH, Miller TA · Plastic and reconstructive surgery · 1 nov 1994
Lymphoscintigraphy has emerged as the diagnostic test of choice in patients with suspected lymphedema. To assess the lymphatic circulation of 386 extremities in 188 patients, we prospectively recorded a semiquantitative index of…
Cambria RA et al. · Journal of vascular surgery · 1 nov 1993
Edemas of the leg sometimes pose problems for diagnosis. Invasive procedures like lymphography or phlebography are either difficult to perform or might endanger the lymphatics. The value of magnetic resonance imaging was assessed…
Werner GT, Rodiek SO · Zeitschrift fur Lymphologie. Journal of lymphology · 1 ago 1993
The authors assessed the use of magnetic resonance imaging in differentiating lymphedema, phlebedema, and lipedema of the lower limb. They examined 14 patients: five with lipedema, five with lymphedema, and four with phlebedema.…
The use of a single axial slice through the mid calf in the differential diagnosis of a swollen leg is described. This is a very simple quick non-invasive investigation. Venous obstruction results in an increase in the cross…
Lipedema is a common disease in the usual clinical practice. None organic description about the clinical symptoms and signs associated to this condition has been published. Fifty women with lipedema have been examined by the…
Bilancini S, Lucchi M, Tucci S · Angiologia · 1 jan 1990
Indirect lymphography by subepidermal infusion of newly developed nonionic, dimeric contrast media (e.g., Iotrolan) opacifies peripheral lymphatics of the skin. Using this method we examined 159 patients with primary and…
Lipedema is a hereditary disease concerning exclusively women. We discuss the characteristics of diagnosis as well as the differential diagnosis between lipedema and primary lymphedema. Therapy is effective if the lipedema…
Schmitz R · Zeitschrift fur Hautkrankheiten · 15 jan 1987
Twelve patients with primary lymphedema of the lower limb were examined with computed tomography (CT). A characteristic "honeycomb" pattern of the subcutaneous compartment was seen in 10 of these patients. CT scans in nine other…
Hadjis NS et al. · AJR. American journal of roentgenology · 1 fev 1985
Patients with lipoedema of the typus rusticanus Moncorps show a skin elasticity deficit of the skin of the calf. This is partly due to the derma oedema in the skin of these patients and seems partly to be due to an intrinsic…
Jagtman BA, Kuiper JP, Brakkee AJ · Phlebologie · 1 jan 1984
Systemic causes of leg edema include idiopathic cyclic edema, heart failure, cirrhosis, nephrosis and other hypoproteinemic states. Lymphedema may be primary, or secondary to neoplasm, lymphangitis, retroperitoneal fibrosis and,…