IntroductionLipedema is a chronic adipose and connective tissue disorder in which pain is classically localized to affected limb tissue. However, some patients report joint, periarticular, myotendinous, or axial pain, with…
BackgroundLipedema is a chronic condition that predominantly affects women and is commonly associated with pain, edema, and functional impairment. Conservative physiotherapy interventions are frequently recommended; however, the…
Aim: This narrative review summarises evidence on pathogenetic mechanisms of adipose tissue remodelling and adipokine dysregulation in lipedema, focusing on adipocyte hypertrophy and hyperplasia, fibrosis, microcirculatory and…
Sierawska O, Dudzińska W · Current issues in molecular biology · 7 out 2026
Lipedema is a chronic, predominantly female disorder characterized by disproportionate regional expansion of subcutaneous adipose tissue, pain, tenderness, and easy bruising. Reported abnormalities involve adipocytes,…
A progressive disease, lipedema is characterized by bilaterally symmetrical and disproportional accumulation of subcutaneous adipose tissue (SAT) in the extremities, leading to severe pain, inflammation, and mobility issues.…
Gohlke S et al. · Frontiers in cell and developmental biology · 1 out 2026
Lipoedema is a painful adipose tissue disorder marked by disproportionate limb fat and often misclassified as generalized obesity or lymphoedema. This review examines its metabolic phenotype and implications for cardiometabolic…
Lipedema is a chronic, progressive, and often underdiagnosed disease characterized by the pathological, bilateral, and symmetrical accumulation of adipose tissue. This distribution results in disproportionate and painful swelling…
Nemes A · Reviews in cardiovascular medicine · 3 set 2026
Lipedema and obesity are often misdiagnosed or clinically confused yet arise via distinct mechanisms, complicating diagnosis and treatment. This review synthesizes evidence differentiating these conditions across genetic,…
Güney YE, Demiralay SÇ, Keser İ · Current issues in molecular biology · 1 set 2026
Lipedema and obesity are chronic, frequently progressive disorders that can present with increased adipose-tissue volume, functional impairment and reduced quality of life. Although often approached as differential diagnoses,…
Lipedema is a chronic disorder characterized by a disproportionate accumulation of subcutaneous adipose tissue in the extremities, typically sparing the hands and feet. It is commonly associated with pain, hypersensitivity, easy…
Lipedema is a chronic inflammatory disorder of adipose tissue that predominantly affects women and is characterized by disproportionate subcutaneous fat accumulation, pain, spontaneous bruising, and significantly impaired quality…
Lima MF · Jornal vascular brasileiro · 20 jul 2026
Background: Endometriosis and lipedema are chronic female-predominant disorders characterized by persistent pain that is frequently disproportionate to anatomical lesion burden. Although traditionally interpreted within distinct…
Lipedema is a chronic adipose tissue disorder characterized by disproportionate fat deposition, pain, and progressive functional impairment. Although diagnosis remains primarily clinical, ultrasound has emerged as a valuable…
Bruno A et al. · Aesthetic plastic surgery · 19 jun 2026
Lipedema is a chronic adipose tissue disorder characterised by disproportionate accumulation of subcutaneous fat within specific anatomical depots, most commonly the lower extremities, with relative sparing of the trunk. Despite…
Reid I et al. · Frontiers in cell and developmental biology · 17 jun 2026
Lipedema is a chronic disorder characterized by disproportionate accumulation of subcutaneous fat, most commonly affecting the extremities, and is associated with pain, inflammation, and fibrosis. Effective medical therapies are…
Mohseni Y et al. · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 18 mai 2026
Lipedema has long been misclassified as a cosmetic concern or a subtype of obesity, leading to delayed diagnosis and suboptimal surgical outcomes. Growing molecular, histopathologic, and imaging evidence supports lipedema as a…
Villa HF, Muñoz J, Padilla-Correa AM · Aesthetic plastic surgery · 11 mai 2026
BackgroundLipedema is a chronic and progressive disorder of subcutaneous adipose tissue that predominantly affects women and is frequently misdiagnosed as obesity, lymphedema, or venous disease. Increasing evidence indicates that…
Lipedema is a chronic, multifactorial disorder characterized by connective tissue dysregulation, in which vascular dysfunction plays a significant role. Lipedema manifests as symmetrical, painful accumulation of adipose tissue,…
Al-Ghadban S et al. · Frontiers in cell and developmental biology · 8 mai 2026
Lipedema has historically been classified within obesity- and lymphedema-related frameworks, despite its distinct clinical features and frequent occurrence in individuals with normal or low body mass index. This narrative review…
Fiengo E, Sbarbati A · Clinical and experimental medicine · 28 abr 2026
Lipedema is a chronic and often debilitating adipose tissue disorder that primarily affects women. The disease is characterized by disproportionate and symmetrical accumulation of subcutaneous fat in the extremities. Despite the…
Soni K, Abbott RD · Frontiers in cell and developmental biology · 21 abr 2026
Lipedema is a chronic, female-predominant disorder of subcutaneous adipose tissue characterized by disproportionate fat expansion, pain, and fibrosis. Despite its high prevalence, the cellular mechanisms underlying lipedema…
Morawitz KH, Gross JC · Frontiers in cell and developmental biology · 31 mar 2026
Lower extremity edema results from an imbalance between capillary hydrostatic pressure, oncotic pressure, and lymphatic drainage, leading to fluid accumulation in the interstitial space. Most cases are bilateral, typically due to…
Greenberg J, Greenberg J, Laurie A · FP essentials · 1 mar 2026
Lipedema is a chronic, progressive adipose tissue disorder characterized by disproportionate subcutaneous fat accumulation, pain, edema, and resistance to conventional weight-loss strategies. Although traditionally conceptualized…
Viana DPdC, Invitti AL, Schor E · International journal of molecular sciences · 1 mar 2026
Lipedema is a chronic condition characterized by abnormal fat accumulation, primarily in the lower extremities, affecting mostly women. Despite improvements in diagnosis and treatment, lipedema is often misdiagnosed as obesity or…
Rathod S, Pouwels S, Schmidt J · JPRAS open · 19 jan 2026
Lipedema is a chronic disease characterized by the symmetrical accumulation of adipose tissue in the lower body, primarily affecting women. Despite being recognized for over 85 years, the pathophysiology, diagnosis, and treatment…
Faria AM et al. · npj metabolic health and disease · 17 jan 2026
Lipedema is a chronic and progressive disorder characterized by disproportionate fat accumulation, mainly affecting the lower extremities of women, and commonly accompanied by sensations of heaviness, tenderness, and discomfort.…
Dal'Forno-Dini T et al. · Anais brasileiros de dermatologia · 8 jan 2026
Background: Emerging evidence suggests that lipedema may share hormonal, inflammatory, and genetic mechanisms with gynecologic diseases, particularly endometriosis. However, the extent and nature of these interrelationships…
Viana DPdC, Invitti AL, Schor E · Biomedicines · 7 jan 2026
Lipedema is a chronic adipose tissue disorder that primarily affects women, characterized by symmetrical and disproportionate fat accumulation in the lower and/ or upper extremities, sparing hands and feet. This review aims to…
IntroductionCompression pressure is the key factor determining effectiveness in compression therapy for venous and lymphatic disorders. Despite its clinical importance, few studies report the actual applied pressure, and national…
Obesity is increasingly recognized not only as a metabolic disorder, but also as a state of chronic low-grade inflammation that predisposes to systemic complications. Within this context, Dercum's disease (DD), or adiposis…
Reytor-González C et al. · International journal of molecular sciences · 18 nov 2025
Lipedema is a chronic disorder characterized by the symmetrical accumulation of subcutaneous adipose tissue, predominantly affecting women. Despite increasing recognition, the pathophysiological mechanisms underlying adipose…
Rabiee A · Frontiers in cell and developmental biology · 6 nov 2025
Lipedema is a chronic, progressive adipose tissue disorder that affects up to 10% of women and is characterized by disproportionate lower-limb fat accumulation, pain, edema, and resistance to conventional weight-loss approaches.…
Viana DPdC, Invitti AL, Schor E · International journal of molecular sciences · 5 nov 2025
Lipedema is a painful chronic disease characterized by symmetric fat tissue accumulation in the lower extremities. Inflammation of the subcutaneous adipose tissue causes pain, edema, and various functional limitations, making…
Aydin A, Bilgic P · Current nutrition reports · 18 out 2025
BackgroundCompression therapy (CT) is widely prescribed for chronic venous disease (CVD), lymphedema, and lipedema despite robust evidence supporting its effectiveness only in a minority of clinical scenarios.AimProvide an…
Estrogen-dependent conditions, such as endometriosis, adenomyosis, lipedema, polycystic ovary syndrome, and breast cancer, are intimately involved with hormonal changes related to estrogen and their receptors. These conditions…
Renke G et al. · Current issues in molecular biology · 27 ago 2025
Lipoedema (lipalgia) is a condition that is often underdiagnosed or misdiagnosed as obesity or lymphoedema, which can result in mismanagement of treatment leading to poor mental and physical outcomes. It is a condition that is…
Crouch M · British journal of nursing (Mark Allen Publishing) · 7 ago 2025
Lipedema is a chronic, estrogen-sensitive adipose tissue disorder characterized by disproportionate subcutaneous fat accumulation, fibrosis, inflammation, and resistance to fat mobilization. Despite its high prevalence, lipedema…
Pinto da Costa Viana D, Caseri Câmara L, Borges Palau R · International journal of molecular sciences · 23 jul 2025
Lipoedema is a disease that affects women and is characterised by an abnormal accumulation of fatty tissue, with pain and a feeling of heaviness in the lower limbs. Approximately 30 % of patients also have involvement of the…
Ekerhovd IW et al. · Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke · 23 jun 2025
Lipedema is an abnormal accumulation of adipose tissue, predominantly observed in women, characterised by symmetrical fat deposition and tactile sensitivity in the extremities, affecting both sides of the body. This condition can…
Sanlier N, Baltacı S · Current obesity reports · 26 mai 2025
Lipodystrophy presents clinical management challenges due to its varied expression and low incidence. Despite the clinical importance, there has been no systematic evaluation of the research output in terms of geographical…
Alsayegh A et al. · Aesthetic plastic surgery · 28 abr 2025
Background/Objectives: Lipedema is a progressive disease that results in the bilateral and symmetrical accumulation of subcutaneous fat in the legs and/or arms, affecting almost exclusively women. Methods: A comprehensive review…
Lipedema is characterized by abnormal fat deposition in areas such as the arms, hips, buttocks, and thighs, sparing the hands and feet. Symptoms include pain, bruising, edema, and subcutaneous nodules, which resist traditional…
Kamamoto F et al. · Jornal vascular brasileiro · 20 jan 2025
Diseases affecting adipose tissue (AT) function include obesity, lipodystrophy, and lipedema, among others. Both a lack of and excess AT are associated with increased risk for developing diseases including type 2 diabetes…
Blüher M · Journal of obesity & metabolic syndrome · 30 dez 2024
Lipedema is a commonly underdiagnosed chronic condition. This study aimed to evaluate liposuction techniques for lipedema by conducting a systematic review and presenting our experience. A case series study and a comprehensive…
Ciudad P et al. · Annals of translational medicine · 17 dez 2024
Lipedematous scalp (LS) and lipedematous alopecia (LA) are uncommon conditions with an unclear cause. Over the past century, about 115 cases have been documented in the literature. It is unknown if these disorders are indeed so…
Koç Yıldırım S · Archives of dermatological research · 26 out 2024
This consensus statement from the Italian Society of Motor and Sports Sciences (Società Italiana di Scienze Motorie e Sportive, SISMeS) and the Italian Society of Phlebology (Società Italiana di Flebologia, SIF) provides the…
Annunziata G et al. · Current obesity reports · 3 jul 2024
Lymphedema and lipedema are chronic debilitating disorders that most commonly affect the upper and lower extremities. Although they can appear similar, they differ in important ways, which the authors of this article review and…
Lomeli LD et al. · Cleveland Clinic journal of medicine · 1 jul 2024
Lipomatoses are benign proliferation of adipose tissue. Lipomas (benign fat tumors) are the most common component of lipomatosis. They may be unique or multiple, encapsulated or not, subcutaneous or sometimes visceral. In some…
Dupuis H et al. · Annales d'endocrinologie · 12 jun 2024
Lipedema is a poorly understood disorder of adipose tissue characterized by abnormal but symmetrical deposition of subcutaneous white adipose tissue (WAT) in proximal extremities. Here, we propose that the underlying cause for…
Kruglikov IL, Scherer PE · Trends in endocrinology and metabolism: TEM · 29 abr 2024
Background: Our aim is to propose a framework for the development of a research case definition of lipedema, based on current available literature and those observations that can be applied to future lipedema research with the…
Keith L et al. · Lymphatic research and biology · 28 mar 2024
This review aims to provide an overview of the current evidence on the efficacy, also considering the anti-inflammatory properties and safety of very low-calorie ketogenic diet (VLCKD) as a potential treatment for lipedema,…
Verde L et al. · Current obesity reports · 4 nov 2023
The aim was to reflect the established interdisciplinary aspects of general/abdominal and plastic surgery by means of a narrative review. Methods: (i) With specific references out of the medical literature and (ii) own clinical…
Kraus A, Damert H, Meyer F · Innovative surgical sciences · 21 set 2023
One of the most common reasons for patient visits in the outpatient practice is lower extremity swelling. Non-cardiac etiologies are the most frequent reason for these encounters. The approach to this patient population will…
Merli GJ, Yenser H, Orapallo D · The Medical clinics of North America · 1 set 2023
Lipohyperplasia dolorosa, also known by the misnomer "lipedema", is a clinical picture first described more than 80 years ago, that in the last 25 years has received increasing attention in medical practices, but also…
Cornely ME · Dermatologie (Heidelberg, Germany) · 17 jul 2023
Pain, which is a central characteristic of lipedema, allows differentiation from other fat tissue diseases. The analysis of the multiple aspects of pain beyond a quantification of pain scale scores could make molecular disease…
Hucho T · Dermatologie (Heidelberg, Germany) · 12 jul 2023
Lipedema is a loose connective tissue disease characterized by a disproportionate accumulation of adipose tissue in the limbs of women. Despite its incidence of 10-20%, lipedema is often underdiagnosed and misdiagnosed. This…
van la Parra RFD et al. · Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 30 mai 2023
Background/Aim: YouTube provides information on several health-conditions including lipedema. The aim of this study was to investigate the properties, quality, and quantity of YouTube videos on lipedema. Methods: We explored…
Esen Özdemir E et al. · Lymphatic research and biology · 16 mar 2023
The lymphatics play important roles in chronic diseases/conditions that comprise the bulk of healthcare worldwide. Yet the ability to routinely image and diagnose lymphatic dysfunction, using commonly available clinical imaging…
Sevick-Muraca EM, Fife CE, Rasmussen JC · Frontiers in physiology · 15 mar 2023
Enhancing our understanding of lymphatic anatomy from the microscopic to the anatomical scale is essential to discern how the structure and function of the lymphatic system interacts with different tissues and organs within the…
Singhal D et al. · Frontiers in physiology · 6 fev 2023
Lipedema, a complex and enigmatic adipose tissue disorder, remains poorly understood despite its significant impact on the patients' quality of life. Genetic investigations have uncovered potential contributors to its…
Bonetti G et al. · La Clinica terapeutica · 1 jan 2023
When studying the current literature, one might get the impression that lipedema is a "modern" disease, with increasing incidence and augmenting prevalence throughout Western countries during the last decade. However, a quick…
Ernst AM et al. · Journal of personalized medicine · 31 dez 2022
Lipoedema is an overlooked and often misdiagnosed condition, which mainly affects women. This review summarises the present knowledge of the condition. It is characterised by bilateral and symmetrical accumulation of subcutaneous…
Andersen MT et al. · Ugeskrift for laeger · 19 dez 2022
Edema of the lower extremities is always associated with a pathological condition that should be treated, especially in patients with chronic wounds. Because the underlying causes of edema can vary greatly and sometimes be…
Stücker M et al. · Dermatologie (Heidelberg, Germany) · 9 dez 2022
Lipedema is an adipofascial disorder that almost exclusively affects women. Lipedema leads to chronic pain, swelling, and other discomforts due to the bilateral and asymmetrical expansion of subcutaneous adipose tissue. Although…
Poojari A, Dev K, Rabiee A · Biomedicines · 30 nov 2022
The most relevant hallmarks of cellulite include a massive protrusion of superficial adipose tissue into the dermis, reduced expression of the extracellular glycoprotein fibulin-3, and an unusually high presence of MUSE cells in…
Kruglikov IL, Scherer PE · Obesity reviews : an official journal of the International Association for the Study of Obesity · 26 out 2022
Lipedema is a chronic disease that mostly manifests in females as the abnormal distribution of subcutaneous adipose connective tissue, usually coupled with bruising, pain, and edema. Lipedema molecular pathophysiology is…
Bonetti G et al. · Journal of preventive medicine and hygiene · 17 out 2022
Lymphedema and lipedema are complex diseases. While the external presentation of swollen legs in lower-extremity lymphedema and lipedema appear similar, current mechanistic understandings of these diseases indicate unique aspects…
Duhon BH et al. · International journal of molecular sciences · 14 jun 2022
Adipose tissue, once thought to be an inert receptacle for energy storage, is now recognized as a complex tissue with multiple resident cell populations that actively collaborate in response to diverse local and systemic…
Westcott GP, Rosen ED · Endocrinology · 1 jan 2022
Lipedema is a painful fat disorder that affects ~11% of the female population. It is characterized by bilateral, disproportionate accumulation of subcutaneous adipose tissue predominantly in the lower body. The onset of lipedema…
Katzer K et al. · International journal of molecular sciences · 29 out 2021
Lipedema is a chronic feminine disease that causes abnormal fat deposition in lower limbs and occasionally upper limbs. Easy bruising and pain are common. Lipedema patients suffer from both physical and psychological disability.…
Forner-Cordero I, Forner-Cordero A, Szolnoky G · International angiology : a journal of the International Union of Angiology · 19 abr 2021
Williams syndrome is a multisystem disorder caused by a microdeletion on chromosome 7q. Throughout infancy, childhood, and adulthood, abnormalities in body composition and in multiple endocrine axes may arise for individuals with…
Stanley TL, Leong A, Pober BR · Current opinion in endocrinology, diabetes, and obesity · 1 fev 2021
Description Adipose tissue (AT) has diverse and important functions in body insulation, mechanical protection, energy metabolism and the endocrine system. Despite its relative abundance in the human body, the clinical…
Lee SW, Van Dien C, Won SJ · HCA healthcare journal of medicine · 29 out 2020
Lipedema is a painful, underdiagnosed adipose tissue disorder, characterized by symmetrical swelling of the extremities due to subcutaneous fat deposition in the buttocks, thighs, legs, and arms, sparing the most distal part of…
Aksoy H, Karadag AS, Wollina U · Dermatologic therapy · 12 out 2020
Lipoedema is associated with widespread adipose tissue expansion, particularly in the proximal extremities. The mechanisms that drive the development of lipoedema are unclear. In this Perspective article, we propose a new model…
Kruglikov IL, Joffin N, Scherer PE · Nature reviews. Endocrinology · 13 ago 2020
Lipedema is often unrecognized or misdiagnosed; despite an estimated prevalence of 10% in the overall female population, its cause is still unknown. There is increasing awareness of this condition, but its differential diagnosis…
Kruppa P et al. · Deutsches Arzteblatt international · 1 jun 2020
Obesity is a leading cause of cardiovascular diseases and cancer. Body mass is regulated by the balance between energy uptake and energy expenditure. The etiology of obesity is determined by multiple factors including genetics,…
Ho Y, Srinivasan RS · Frontiers in physiology · 22 jan 2020
Lipedema is a chronic and progressive disease of adipose tissue caused by abnormal fat accumulation in subcutaneous tissue. Although there is no known cure for lipedema, possible complications can be prevented with conservative…
Lipedema is a chronic progressive disease characterized by abnormal fat distribution resulting in disproportionate, painful limbs. It almost exclusively affects women, leading to considerable disability, daily functioning…
Buso G et al. · Obesity (Silver Spring, Md.) · 1 out 2019
Syndromes with localized accumulation of subcutaneous fatty tissue belong to a group of genetically and phenotypically heterogeneous disorders. These diseases may show some common signs, such as nodular fat, symmetrical fat…
Precone V et al. · Acta bio-medica : Atenei Parmensis · 30 set 2019
The aim of this qualitative review is to provide an update on the current understanding of the genetic determinants of lipedema and to develop a genetic test to differentiate lipedema from other diagnoses. An electronic search…
Paolacci S et al. · European review for medical and pharmacological sciences · 1 jul 2019
The aim of this narrative review of the literature was to evaluate and summarize the current literature regarding the effect of lipedema on health-related quality of life (HRQOL) and psychological status. The authors collected…
Alwardat N et al. · Eating and weight disorders : EWD · 6 mai 2019
Although liposuction of lipoedema is a well-established therapeutic option in plastic and reconstructive surgery, the commonly known operative protocols vary widely between clinics. A precise summary of all described protocols…
Ghods M, Kruppa P · Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 8 jan 2019
Lipoedema is a chronic disorder of adipose tissue, characterised by disproportionate fat deposits in the lower limbs and pain with preservation of the feet. The condition usually only affects women. Diagnosis is clinical and…
Redondo Galán C, García Bascones M, Marquina Valero MA · Rehabilitacion · 1 jan 2019
Lipedema is a chronic disabilitating disease affecting the subcutaneous adipose tissue of the extremities in females during or after puberty. The disease is characterized by bilateral swelling of legs and/or arms, bruising, and…
Lymphedema is a complex disease process with deranged lymphatic transport, fluid accumulation and secondary lipedema and fibrosis. This is a challenging disease to treat with a surgical focus on debulking and physiologic…
Gould DJ et al. · Journal of surgical oncology · 21 ago 2018
Lipoedema is a rare painful disorder of the adipose tissue. It essentially affects females and is often misdiagnosed as lymphoedema or obesity. It is globally misdiagnosed or underdiagnosed, and the literature is lacking…
Shavit E, Wollina U, Alavi A · International wound journal · 29 jun 2018
Background Lipedema is a chronic disorder presenting in women during puberty or other times of hormonal change such as childbirth or menopause, characterized by symmetric enlargement of nodular, painful subcutaneous adipose…
Torre YSl et al. · Hormone molecular biology and clinical investigation · 9 mar 2018
Lipoedema is a disorder of adipose tissue that is characterized by abnormal subcutaneous fat deposition, leading to swelling and enlargement of the lower limbs as well as the trunk. This entity is often misdiagnosed as…
Lipedema: Which Etiological Pathways? Abstract. The pathogenesis and epidemiology of lipedema are uncertain, and its diagnosis often delayed. Lipedema almost exclusively affects women, and a link to sex hormones is likely. The…
Surgical Treatment for Lipedema Abstract. Lipedema is a progressive disease that occurs in adolescence and affects one in nine women. The signs are limited to the lower limbs. Early signs are nonspecific, which is why the…
Lipedema, the Unknown Abstract. Lipoedema patients suffer from the widespread ignorance of their pathology. Considering its chronic, progressive and invalidating character, the early diagnosis of the disease must constitute the…
Lipedema an often overlooked but treatable disease Lipedema is a painful disease that affects some women between puberty and menopause through a subcutaneous fat accumulation especially in the lower extremities. Patients suffer…
Perbeck L, Mellgrim S · Lakartidningen · 13 nov 2017
Nowadays, liposuction is the most frequently performed aesthetic surgery procedure in Western Countries. This technique has had rapid development since the 1970s, when it was experimented for the first time by A. and G. Fischer.…
Bellini E, Grieco MP, Raposio E · Annals of medicine and surgery (2012) · 6 nov 2017
Lipoedematous scalp (LS) is an extremely rare condition characterised by a soft and boggy consistency in the scalp due to an increased layer of subcutaneous tissue.In this report, we present a case of LS in a 64-year-old Indian…
Law S, Jayarajan R · BMJ case reports · 9 out 2017
Lipedema is a chronic disorder of subcutaneous adipose tissue of unknown etiology not uncommon among post-puberty women. The disease has a negative impact on self-esteem, mobility, and quality of life. Lipedema is characterized…
Wollina U · Wiener medizinische Wochenschrift (1946) · 10 mai 2017
Lower extremity edema is extremely common among patients seen across multiple specialties. The differential diagnosis is broad and ranges from simple dependent edema to more complex conditions such as chronic venous disease and…
Ratchford EV, Evans NS · Current treatment options in cardiovascular medicine · 1 mar 2017
Lymphedema results from impaired lymphatic transport with increased limb volume. Lymphedema are divided in primary and secondary forms. Upper-limb lymphedema secondary to breast cancer treatment is the most frequent in France.…
Vignes S · La Revue de medecine interne · 31 ago 2016
Lipedema is an uncommon disorder characterized by localized adiposity of the lower extremities, often occurring in females with a family history of the condition. The adiposity extends from hips to ankles and is typically…
Warren Peled A, Kappos EA · International journal of women's health · 11 ago 2016
Compression therapy is a key component in the effective management of people with lower limb problems associated with venous, lymphatic and fat disorders such as lipoedema. Individuals with lymphoedema, venous ulceration and…
At present, there is no proven cure for lipoedema. Nevertheless, much can be done to help improve symptoms and prevent progression. Many of these improvements can be achieved by patients using self-management techniques. This…
Fetzer A, Wise C · British journal of community nursing · 1 out 2015
Liposuction is the most common cosmetic surgical procedure worldwide. It has evolved from being designed primarily for body contouring to becoming essential adjunct to various other aesthetic procedures, greatly enhancing their…
Atiyeh B et al. · Annals of plastic surgery · 1 ago 2015
Lipedema is a disorder of adipose tissue that primarily affects females and is often misdiagnosed as obesity or lymphedema. Relatively few studies have defined the precise pathogenesis, epidemiology, and management strategies for…
Okhovat J, Alavi A · The international journal of lower extremity wounds · 17 out 2014
Lipedema is a common, but often underdiagnosed masquerading disease of obesity, which almost exclusively affects females. There are many debates regarding the diagnosis as well as the treatment strategies of the disease. The…
Leg swelling is an extremely frequent symptom with a broad variety of largely differing causes. The most important mechanisms behind the symptom include venous and lymphatic pathology, volume overload, increased capillary…
Due to its increased presence in the press and on television, the diagnosis of lipedema is on the way to becoming a trendy diagnosis for those with thick legs. Despite this, one must recognize that lipedema is a very rare…
Reich-Schupke S, Altmeyer P, Stücker M · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 11 dez 2012
The International Compression Club (ICC) is a partnership between academics, clinicians and industry focused upon understanding the role of compression in the management of different clinical conditions. The ICC meet regularly…
Flour M et al. · International wound journal · 21 jun 2012
Lipedema is a clinical entity frequently misdiagnosed or confound with primary lymphedema. Lipedema is a disorder of adipose tissue that occurs almost exclusively in obese women. It is characterized by bilateral enlargement from…
Vignes S · Journal des maladies vasculaires · 13 jun 2012
DEFINITION AND CLINICAL PICTURE: We propose the minimal definition of Dercum's disease to be generalised overweight or obesity in combination with painful adipose tissue. The associated symptoms in Dercum's disease include fatty…
Hansson E, Svensson H, Brorson H · Orphanet journal of rare diseases · 30 abr 2012
Rare adipose disorders (RADs) including multiple symmetric lipomatosis (MSL), lipedema and Dercum's disease (DD) may be misdiagnosed as obesity. Lifestyle changes, such as reduced caloric intake and increased physical activity…
Lymphedema and lipedema are chronic progressive disorders for which no causal therapy exists so far. Many general practitioners will rarely see these disorders with the consequence that diagnosis is often delayed. The…
There are many causes for a large lower limb in the pediatric age group. These children are often mislabeled as having lymphedema, and incorrect diagnosis can lead to improper treatment. The purpose of this study was to determine…
Schook CC et al. · Plastic and reconstructive surgery · 1 abr 2011
To enhance the learner's competence in caring for patients with lipedema through understanding the differential diagnoses, pathophysiology, and treatment/management options. This continuing education activity is intended for…
Fife CE, Maus EA, Carter MJ · Advances in skin & wound care · 1 fev 2010
Overweight and obesity is a public health problem in Hungary and in the Western world. It is important to underline that obesity is an illness and an important risk factor for several skin and other diseases. An overview of skin…
Lipoedema is an infrequently recognized disorder in women. Lipoedema is characterized by bilateral enlargement of the legs due to abnormal depositions of subcutaneous fat associated with often mild oedema. There is substantial…
Langendoen SI et al. · The British journal of dermatology · 20 jul 2009
Lipedema is a common but rarely diagnosed disease or frequently confused with obesity. Patients are almost exclusively women. It is characterised by symmetrical, circumscribed, in advanced form deforming fat tissue accumulation…
Lymphoedema is a clinical manifestation of an impaired lymphatic drainage with accumulation of lymphatic fluid. Lipoedema is characterized by bilateral enlargement of the legs and/or arms due to abnormal deposition of fatty…
Lymphatic disease is quite prevalent, and often not well clinically characterized. Beyond lymphedema, there is a broad array of human disease that directly or indirectly alters lymphatic structure and function. The symptomatic…
Radhakrishnan K, Rockson SG · Annals of the New York Academy of Sciences · 1 jan 2008
Fluorescence microlymphography (FML) is an almost atraumatic technique used to visualize the superficial skin network of initial lymphatics through the intact skin of man. Visualization was performed with an incident light…
Bollinger A, Amann-Vesti BR · Lymphology · 1 jun 2007
After studying this article, the participant should be able to: 1. Discuss the initial evaluation of a patient presenting with lower extremity enlargement. 2. Distinguish underlying medical conditions causing lower extremity…
Warren AG et al. · Plastic and reconstructive surgery · 1 jan 2007
Through the appropriate use of tumescent anesthesia and the use of modern instruments and techniques, liposuction surgery has become a low-risk procedure which produces predictable and aesthetically pleasing results. New…
Sattler G, Bergfeld D, Sommer B · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 jul 2004
Because of the lifelong and often progressive course and the mental trauma to the patients, lipoedema is an important dermatologic disorder. Complex physical therapy programs were introduced as a standard therapy years ago and…
Meier-Vollrath I, Schmeller W · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 1 mar 2004
As the science of wound healing has evolved over the past two decades, so has awareness of the "hidden epidemic" of lymphedema. Substantial information has been accumulated regarding the pathophysiology and therapy of lymphedema.…
Macdonald JM, Sims N, Mayrovitz HN · The Surgical clinics of North America · 1 jun 2003
The causes and management of lower limb lymphedema in the Western population are different from those in the developing world. To look at the differential diagnosis, methods of investigation, and available treatments for lower…
Tiwari A et al. · Archives of surgery (Chicago, Ill. : 1960) · 1 fev 2003
Methods for lymphatic imaging are numerous and can be roughly classified as anatomic or functional studies. Direct or indirect lymphographies provide useful informations in case of lymphostasis. Contrast lymphangiography is the…
Pecking AP, Desprez-Curely JP, Cluzan RV · La Revue de medecine interne · 1 jun 2002
Lipedematous alopecia is a rare condition of unknown etiology characterized by a thick, boggy scalp with varying degrees of hair loss that occurs in adult black females, with no clearly associated medical or physiologic…
Fair KP et al. · Journal of cutaneous pathology · 1 jan 2000
The "Lipedema" or "Fatedema" is conditioned by a slight mechanical obstruction of the small lymphatic vessels by the increasing pressure of the growing fat tissue. This lymphostasis in a normal lymphatic vessel system arises only…
Herpertz U · Zeitschrift fur Lymphologie. Journal of lymphology · 1 ago 1995
Microlymphatics of human skin form two superposed networks. The superficial one located at the level of dermal papillae may be visualized by fluorescence microlymphography. Microlymphatics fill from a subepidermal depot of minute…
Bollinger A · International journal of microcirculation, clinical and experimental · 1 fev 1993
An overall view of the clinical findings in lipedema is given and of its treatment. Lipedema is shown to be a distinct illness, and not just a disturbance of the distribution pattern of subcutaneous fatty tissue. The diagnosis is…
Wienert V, Leeman S · Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1 ago 1991
Leg swelling is often of edematous nature. The most important differential diagnosis lies in the distinction between venous or lymphatic forms of edema. An increased vascular permeability and alterations in blood composition have…
Ludwig M, Vetter H · Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis · 12 set 1989